ChemicalBook >> CAS DataBase List >>EPROSARTAN

EPROSARTAN

EPROSARTAN structure

CAS No.: 133040-01-4

Chemical Name:: EPROSARTAN

Synonyms: Epsartan;Teveten;Navixen;CS-1951;EPROSARTAN;SKB 108566;SKF-108566J;SKF-108566);Eprosartan-d4;prop-1-en-1-yl)

CBNumber:: CB0135346

Molecular Formula:: C23H24N2O4S

Molecular Weight:: 424.51

MDL Number:: MFCD00897872

MOL File:: 133040-01-4.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-27 17:18:23

Product description	Number	Pack Size	Price
Eprosartan >95%(HPLC)	TRC-E590100-50MG	50mg	$209
Eprosartan >95%(HPLC)	TRC-E590100-25MG	25mg	$158
Eprosartan >95%(HPLC)	TRC-E590100-10MG	10mg	$100
Eprosartan	FE22770	5mg	$150
Eprosartan	FE22770	50mg	$150
More product size

Request For Quotation

EPROSARTAN Properties

Melting point	250-253°C
storage temp.	Sealed in dry,2-8°C
solubility	Dichloromethane (Slightly), Methanol (Slightly)
form	Solid
color	Pale Yellow to Light Yellow
CAS DataBase Reference	133040-01-4
FDA UNII	2KH13Z0S0Y
ATC code	C09CA02

Pharmacokinetic data

Protein binding	98%
Excreted unchanged in urine	<2 (as metabolites)
Volume of distribution	13 Litres
Biological half-life	5-9 / Unchanged

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319
Precautionary statements	P305+P351+P338
Hazardous Substances Data	133040-01-4(Hazardous Substances Data)

EPROSARTAN price More Price(47)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	TRC-E590100-50MG	Eprosartan >95%(HPLC)	133040-01-4	50mg	$209	2026-06-03	Buy
TRC	TRC-E590100-25MG	Eprosartan >95%(HPLC)	133040-01-4	25mg	$158	2026-06-03	Buy
TRC	TRC-E590100-10MG	Eprosartan >95%(HPLC)	133040-01-4	10mg	$100	2026-06-03	Buy
Biosynth	FE22770	Eprosartan	133040-01-4	5mg	$150	2026-06-04	Buy
Biosynth	FE22770	Eprosartan	133040-01-4	50mg	$150	2026-06-04	Buy

Product number	Packaging	Price	Buy
TRC-E590100-50MG	50mg	$209	Buy
TRC-E590100-25MG	25mg	$158	Buy
TRC-E590100-10MG	10mg	$100	Buy
FE22770	5mg	$150	Buy
FE22770	50mg	$150	Buy

EPROSARTAN Chemical Properties,Uses,Production

Description

Teveten was launched in Germany for the treatment of hypertension. There are several ways in which it has been prepared, the shortest of which is four steps; beginning with displacement of 2-butyl-4-chloroimidazole-5-carboxaldehyde with methyl 4-(bromomethyl)benzoate. Teveten is an angiotensin Ⅱ antagonist selective for the AT, subtype receptor. It is a potent, highly selective, competitve antagonist with no agonist activity. Duration of action is similar to Enalapril (greater than 12 hr) but Teveten had a faster onset. While it is orally active, it rapidly dissociates from the receptor. This is contrary to its prolonged duration of action, which presumably results from slow removal from compartments within tissue, cells or matrix around the AT, receptor. It is not bound by BSA.

Chemical Properties

Light-Yellow Solid

Originator

SmithKline Beecham (UK)

Uses

Prototype of the imidazoleacrylic acid angiotensin II receptor antagonists. Antihypertensive

Uses

Eprosartan is a prototype of the imidazoleacrylic acid angiotensin II receptor antagonists. Eprosartan is an antihypertensive.

Uses

Eprosartan (E590100) impurity.

Definition

ChEBI: A member of the class of imidazoles and thiophenes that is an angiotensin II receptor antagonist used for the treatment of high blood pressure.

brand name

Teveten

Clinical Use

Angiotensin-II antagonist
Hypertension

Drug interactions

Potentially hazardous interactions with other drugs Anaesthetics: enhanced hypotensive effect.
Analgesics: antagonism of hypotensive effect and increased risk of renal impairment with NSAIDs; hyperkalaemia with ketorolac and other NSAIDs.
Antihypertensives: increased risk of hyperkalaemia hypotension and renal impairment with ACE inhibitors and aliskiren.
Ciclosporin: increased risk of hyperkalaemia and nephrotoxicity.
Diuretics: enhanced hypotensive effect; hyperkalaemia with potassium-sparing diuretics.
Epoetin: increased risk of hyperkalaemia; antagonism of hypotensive effect.
Lithium: reduced excretion, possibility of enhanced lithium toxicity.
Potassium salts: increased risk of hyperkalaemia.
Tacrolimus: increased risk of hyperkalaemia and nephrotoxicity.

Metabolism

Following oral and intravenous dosing with [14C] eprosartan in human subjects, eprosartan was the only drug-related compound found in the plasma and faeces. In the urine, approximately 20% of the radioactivity excreted was an acyl glucuronide of eprosartan with the remaining 80% being unchanged eprosartan
Eprosartan is eliminated by both biliary and renal excretion. Following intravenous [14C] eprosartan, about 61% of radioactivity is recovered in the faeces and about 37% in the urine. Following an oral dose of [14C] eprosartan, about 90% of radioactivity is recovered in the faeces and about 7% in the urine.

EPROSARTAN synthesis

Synthesis of EPROSARTAN from METHYL 4-[(2-BUTYL-5-FORMYL-1H-IMIDAZOL-1-YL)METHYL]BENZOATE and 2-Carbethoxy-3-(2-thienyl)propanoic acid

EPROSARTAN Preparation Products And Raw materials

Raw materials

Clotrimazole Methyl 4-(bromomethyl)benzoate 2-Carbethoxy-3-(2-thienyl)propanoic acid Methyl acrylate 1H-Imidazole-5-propanoic acid, 2-butyl-β-hydroxy-1-[[4-(methoxycarbonyl)phenyl]methyl]-α-(2-thienylmethyl)-, methyl ester

133040-02-5 METHYL 4-[(2-BUTYL-5-FORMYL-1H-IMIDAZOL-1-YL)METHYL]BENZOATE Methyl (E)-3-[2-Butyl-1-[(4-Carbomethoxyphenyl)methyl]imidazol-5-yl]-2-(2-thienylmethyl)-2-propenoate Eprosartan Ethyl Methyl Diester Methyl-3-(2-thienyl)=propionate

2-Butyl-4-chloro-5-formylimidazole

1of3

Preparation Products

EPROSARTAN Suppliers

Global( 140)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Moxin Chemicals	+86-17320513646 +8617320513646	anna@molcoo.com	China	10000	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21587	55
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30225	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23541	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	9996	58
AFINE CHEMICALS LIMITED	+86-0571-85134551	sales@afinechem.com	China	15083	58
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19853	58

Supplier	Advantage
Moxin Chemicals	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
CONIER CHEM AND PHARMA LIMITED	58
TargetMol Chemicals Inc.	58
Career Henan Chemica Co	58
ANHUI WITOP BIOTECH CO., LTD	58
Shaanxi Dideu Medichem Co. Ltd	58
AFINE CHEMICALS LIMITED	58
BOC Sciences	58

View Lastest Price from EPROSARTAN manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-05-26	Eprosartan 133040-01-4	$39.00-105.00		99.99%	10g	TargetMol Chemicals Inc.
2025-12-16	Eprosartan 133040-01-4		10mg	98	10000000	Moxin Chemicals
2020-05-10	Eprosartan 133040-01-4		1KG	99.0%	500 MT	Shaanxi Dideu Medichem Co. Ltd

Eprosartan
133040-01-4
$39.00-105.00
99.99%
TargetMol Chemicals Inc.

Eprosartan
133040-01-4
98
Moxin Chemicals

Eprosartan
133040-01-4
99.0%
Shaanxi Dideu Medichem Co. Ltd

EPROSARTAN Spectrum

EPROSARTAN(133040-01-4)¹HNMR

133040-01-4(EPROSARTAN)Related Search:

SB 206328 CINITAPRIDE HYDROGEN TARTRATE 4-(2-BUTYL-5-FORMYLIMIDAZOL-1-YLMETHYL)BENZOIC ACID Tacrolimus Losartan potassium

Pregabalin Irbesartan Valsartan Eprosartan mesylate Olmesartan Medoxomil

Tasosartan 4-Bromomethylbenzoic acid SB 201972 3-(2-THIENYL)PROPIONIC ACID Methyl (E)-3-[2-Butyl-1-[(4-Carbomethoxyphenyl)methyl]imidazol-5-yl]-2-(2-thienylmethyl)-2-propenoate

Epalrestat iMpurity 4-(Hydroxymethyl)benzoic acid α-Methylcinnamaldehyde

1of4

4-[2-Butyl-5-(2-carboxy-3-thiophen-2-yl-propenyl)-imidazol-1-ylmethyl]-benzoic acid EPROSARTAN Eprosartan Mysylate (E)-3-[2-Butyl-1-[(4-carboxyphenyl)-methyl]imidazol-5-l]-2-(2-thienylmethyl)-2-propenoic Acid ((E)-3-[2-Butyl-1-[(4-carboxyphenyl)methyl]imidazol-5-yl]-2-(2-thienylmethyl)-2-propenoic Acid SKF-108566) SKF-108566J Teveten (E)- α-[[2-Butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-y1]methylene]2-thiophenepropanoic acid (E)-3-[2-Butyl-1-(4-carboxybenzyl)-1H-imidazol-5-yl]-2-(2-thienylmethyl)acrylic acid 2-Thiophenepropanoic acid, α-[[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-, (αE)- Des[2-(2-thienylMethyl)] Eprosartan-2-carboxylic Acid (E)-2-Butyl-1-(p-carboxybenzyl)-α-2-thenyliMidazole-5-acrylic Acid (αE)-α-[[2-Butyl-1-[(4-carboxyphenyl)Methyl]-1H-iMidazol-5-yl]Methylene]-2-thiophenepropanoic Acid Navixen SKB 108566 2-[[2-Butyl-1-[[4-(carboxyphenyl)]Methyl]-1H-iMidazol-5-yl]Methylene]propanedioic Acid 4-[[2-Butyl-5-(2,2-dicarboxyvinyl)-1H-iMidazol-1yl)Methylbenzoic Acid Eprosartan-d4 (E)-4-((2-Butyl-5-(2-carboxy-3-(thiophen-2-yl)prop-1-en-1-yl)-1H-iMidazol-1-yl)Methyl)benzoic acid -1H-imidazol-1-yl) -4-((2-Butyl-5-(2-carboxy-3-(thiophen-2-yl) prop-1-en-1-yl) CS-1951 EPROSARTAN USP/EP/BP Eprosartan D6 HClQ: What is Eprosartan D6 HCl Q: What is the CAS Number of Eprosartan D6 HCl Q: What is the storage condition of Eprosartan D6 HCl Q: What are the applications of Eprosartan D6 HCl EprosartanQ: What is Eprosartan Q: What is the CAS Number of Eprosartan Q: What is the storage condition of Eprosartan Q: What are the applications of Eprosartan TIANFU-CHEM EPROSARTAN Eprosartan (SKF-108566J) 13C6]-Eprosartan Eprosartan (E)-3-[2-Butyl-1-[(4-carboxyphenyl)methyl]-imidazol-5-yl]-2-(2- thienyl methyl)-2-propenoic acid Eprosartan in methanol Eprosartan, 10 mM in DMSO Epsartan 133040-01-4 C23H24N2O4S Aromatics Heterocycles Impurities Intermediates Intermediates & Fine Chemicals Pharmaceuticals Sulfur & Selenium Compounds

一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

EPROSARTAN

EPROSARTAN Properties

Pharmacokinetic data

SAFETY

Risk and Safety Statements

EPROSARTAN price More Price(47)

EPROSARTAN Chemical Properties,Uses,Production

Description

Chemical Properties

Originator

Uses

Uses

Uses

Definition

brand name

Clinical Use

Drug interactions

Metabolism

EPROSARTAN synthesis

EPROSARTAN Preparation Products And Raw materials

Raw materials

Preparation Products

EPROSARTAN Suppliers

View Lastest Price from EPROSARTAN manufacturers

EPROSARTAN Spectrum

133040-01-4(EPROSARTAN)Related Search: