BENZYL 4-(BROMOMETHYL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE
- CAS No.
- 159275-17-9
- Chemical Name:
- BENZYL 4-(BROMOMETHYL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE
- Synonyms
- BENZYL 4-(BROMOMETHYL)PIPERIDINE-1-CARBOXYLATE;BUTTPARK 95\50-67;N-Cbz-4-(broMoMethyl)piperidine;1-CBZ-4-(BROMOMETHYL)PIPERIDINE;4-(bromomethyl)piperidine-1-carboxylate;4-(Bromomethyl)piperidine, N-CBZ protected;benzyl 4-(broMoMethyl)piperidine-N-carboxylate;N-(BENZYLOXYCARBONYL)-4-(BROMOMETHYL)PIPERIDINE;N-(Benzyloxycarbonyl)-4-(bromomethyl)piperidine, 98 %;benzyl 4-(bromomethyl)hexahydropyridine-1-carboxylate
- CBNumber:
- CB0136222
- Molecular Formula:
- C14H18BrNO2
- Molecular Weight:
- 312.2
- MDL Number:
- MFCD02681989
- MOL File:
- 159275-17-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 1-CBZ-4-(BROMOMETHYL)PIPERIDINE 97% | 57160 | 1G | $33 |
| 1-CBZ-4-(BROMOMETHYL)PIPERIDINE 97% | 57160 | 5G | $99 |
| 1-CBZ-4-(BROMOMETHYL)PIPERIDINE 97% | 57160 | 25G | $422 |
| 4-(Bromomethyl)piperidine, N-CBZ protected 98% | OR23105 | 250mg | $45 |
| 4-(Bromomethyl)piperidine, N-CBZ protected 98% | OR23105 | 1g | $102 |
| More product size | |||
| Melting point | 68 °C |
|---|---|
| Boiling point | 403.4±28.0 °C(Predicted) |
| Density | 1.356±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C, stored under nitrogen |
| pka | -1.96±0.40(Predicted) |
| Appearance | White to off-white Solid |
| InChI | InChI=1S/C14H18BrNO2/c15-10-12-6-8-16(9-7-12)14(17)18-11-13-4-2-1-3-5-13/h1-5,12H,6-11H2 |
| InChIKey | XJHKDSZGAWXUTB-UHFFFAOYSA-N |
| SMILES | N1(C(OCC2=CC=CC=C2)=O)CCC(CBr)CC1 |
| CAS DataBase Reference | 159275-17-9(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
| Hazard Codes | Xi,C |
| Risk Statements | 36/37/38-34 |
| Safety Statements | 26-36/37/39-45 |
| Hazard Note | Irritant |
| HS Code | 2933399990 |
BENZYL 4-(BROMOMETHYL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE price More Price(49)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AstaTech | 57160 | 1-CBZ-4-(BROMOMETHYL)PIPERIDINE 97% | 159275-17-9 | 1G | $33 | 2026-04-30 | Buy |
| AstaTech | 57160 | 1-CBZ-4-(BROMOMETHYL)PIPERIDINE 97% | 159275-17-9 | 5G | $99 | 2026-04-30 | Buy |
| AstaTech | 57160 | 1-CBZ-4-(BROMOMETHYL)PIPERIDINE 97% | 159275-17-9 | 25G | $422 | 2026-04-30 | Buy |
| Apolloscientific | OR23105 | 4-(Bromomethyl)piperidine, N-CBZ protected 98% | 159275-17-9 | 250mg | $45 | 2026-06-04 | Buy |
| Apolloscientific | OR23105 | 4-(Bromomethyl)piperidine, N-CBZ protected 98% | 159275-17-9 | 1g | $102 | 2026-06-04 | Buy |
BENZYL 4-(BROMOMETHYL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE Chemical Properties,Uses,Production
Synthesis
122860-33-7
159275-17-9
Under nitrogen atmosphere, benzyl 4-(hydroxymethyl)piperidine-1-carboxylate (10 g, 40.11 mmol) was added to a 500 mL three-necked round-bottomed flask, dissolved in dichloromethane (100 mL), and the mixture was cooled to 0 °C. Subsequently, a solution of triphenylphosphine (13.7 g, 52.14 mmol) in dichloromethane (50 mL) was slowly added to the reaction mixture and kept stirring at 0°C for 20 minutes. Next, a dichloromethane (50 mL) solution of carbon tetrabromide (16 g, 48.13 mmol) was added and the reaction mixture was brought to room temperature and stirred for 3 hours. Upon completion of the reaction, the reaction mixture was diluted with dichloromethane and washed with deionized water. The organic layer was separated, dried with anhydrous sodium sulfate and concentrated under reduced pressure. Finally, purification by column chromatography afforded benzyl 4-(bromomethyl)piperidine-1-carboxylate (10 g).
References
[1] Journal of Medicinal Chemistry, 2005, vol. 48, # 10, p. 3586 - 3604
[2] Journal of Medicinal Chemistry, 2003, vol. 46, # 13, p. 2606 - 2620
[3] Patent: WO2015/195950, A1. Location in patent: Page/Page column 82
[3] Patent: , 2015, . Location in patent: Page/Page column 82
BENZYL 4-(BROMOMETHYL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52704 | 58 |
| Henan Alfa Chemical Co., Ltd | +8615838112936 | sale03@alfachem.cn | China | 9796 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49962 | 58 |
| Zhengzhou Anbu Chem Co.,Ltd | +86-0371-88006763; +8615988602810 | sales@anbuchem.com | China | 3016 | 58 |
View Lastest Price from BENZYL 4-(BROMOMETHYL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-08-11 | BENZYL 4-(BROMOMETHYL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE
159275-17-9
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2019-07-06 | BENZYL 4-(BROMOMETHYL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE
159275-17-9
|
$1.00 | 1kg | 95%-99% | 100kg | Career Henan Chemical Co |
-
- BENZYL 4-(BROMOMETHYL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE
159275-17-9
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- BENZYL 4-(BROMOMETHYL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE
159275-17-9
- $1.00
- 95%-99%
- Career Henan Chemical Co
