N-CHLOROSACCHARIN
- CAS No.
- 14070-51-0
- Chemical Name:
- N-CHLOROSACCHARIN
- Synonyms
- N-CHLOROSACCHARIN;N-Chlorosaccharin 99%;N-Chlorosaccharin,98%;N-Chlorosaccharin;2-CHLORO-1,2-BENZISOTHIAZOL-3(2H)ONE 1,1-DIOXIDE;2-Chlorobenzo[d]isothiazol-3(2H)-one 1,1-dioxide;1,2-Benzisothiazol-3(2H)-one, 2-chloro-, 1,1-dioxide
- CBNumber:
- CB0141033
- Molecular Formula:
- C7H4ClNO3S
- Molecular Weight:
- 217.63
- MDL Number:
- MFCD00274277
- MOL File:
- 14070-51-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| N-Chlorosaccharin 99% | 452742 | 25g | $183 |
| N-Chlorosaccharin >96.0%(T) | C1674 | 5g | $211 |
| N-Chlorosaccharin >96.0%(T) | C1674 | 25g | $620 |
| N-Chlorosaccharin | PAA07051 | 25g | $931.25 |
| N-Chlorosaccharin | PAA07051 | 50g | $1489.5 |
| Melting point | 148-152 °C (lit.) |
|---|---|
| Boiling point | 388.6±25.0 °C(Predicted) |
| Density | 1.77±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | soluble in Toluene |
| form | powder to crystaline |
| pka | -24.37±0.20(Predicted) |
| color | White to Almost white |
| InChI | InChI=1S/C7H4ClNO3S/c8-9-7(10)5-3-1-2-4-6(5)13(9,11)12/h1-4H |
| InChIKey | VKWMGUNWDFIWNW-UHFFFAOYSA-N |
| SMILES | S1(=O)(=O)C2=C(C=CC=C2)C(=O)N1Cl |
| CAS DataBase Reference | 14070-51-0 |
| FDA UNII | G35NK0CTFF |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H312-H332-H351 | |||||||||
| Precautionary statements | P280 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 20/21/22-40 | |||||||||
| Safety Statements | 22-26-36/37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29251100 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Carc. 2 |
|||||||||
| NFPA 704 |
|
N-CHLOROSACCHARIN price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 452742 | N-Chlorosaccharin 99% | 14070-51-0 | 25g | $183 | 2023-01-07 | Buy |
| TCI Chemical | C1674 | N-Chlorosaccharin >96.0%(T) | 14070-51-0 | 5g | $211 | 2026-04-30 | Buy |
| TCI Chemical | C1674 | N-Chlorosaccharin >96.0%(T) | 14070-51-0 | 25g | $620 | 2026-04-30 | Buy |
| Biosynth | PAA07051 | N-Chlorosaccharin | 14070-51-0 | 25g | $931.25 | 2026-06-04 | Buy |
| Biosynth | PAA07051 | N-Chlorosaccharin | 14070-51-0 | 50g | $1489.5 | 2026-06-04 | Buy |
N-CHLOROSACCHARIN Chemical Properties,Uses,Production
Chemical Properties
White to off-white crystalline powder
Synthesis
81-07-2
14070-51-0
1. Saccharin (6.0 g) was dissolved in methanol (120 mL), stirred at room temperature, tert-butyl hypochlorite (5 mL) was added slowly, and the reaction was carried out for 5 min to obtain N-chlorophthaloylbenzimide intermediate 1a (6.0 g, 84% yield). 2. Intermediate 1a (3.0 g) was mixed with silver trifluoromethylsulfide (3.6 g) in acetonitrile (40 mL), and the reaction was stirred at room temperature for 10 min to obtain the target product N-chlorophthaloylbenzimide 1 (3.3 g, 86% yield). Note: The product 1 is a white solid at room temperature, easily soluble in organic solvents such as dichloromethane, chloroform, acetone and acetonitrile.
References
[1] Synlett, 2006, # 2, p. 194 - 200
[2] Angewandte Chemie, International Edition, 2014, vol. 53, # 35, p. 9316 - 9320,5
[3] Angewandte Chemie, 2014, vol. 126, # 35, p. 9470 - 9474,5
[4] Patent: CN104945294, 2016, B. Location in patent: Paragraph 0135; 0136; 0137; 0138
[5] Patent: CN104945298, 2016, B. Location in patent: Paragraph 0187; 0188; 0189; 0190
N-CHLOROSACCHARIN Preparation Products And Raw materials
N-CHLOROSACCHARIN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33324 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Qingdao Dexin Chemical Co., Ltd | +86-15553333686 | 15553333686@qq.com | China | 3113 | 58 |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
| Shandong Jiuyue Biotechnology Co., Ltd. | 15553333686 | 643971@qq.com | China | 790 | 58 |
| Shandong Mingde Biotechnology Co., Ltd | 15553348166 | m15553348166@163.com | China | 2024 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40228 | 62 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24529 | 81 |
