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ChemicalBook >> CAS DataBase List >>(6-AMINO-3-PYRIDINYL)METHANOL

(6-AMINO-3-PYRIDINYL)METHANOL

CAS No.
113293-71-3
Chemical Name:
(6-AMINO-3-PYRIDINYL)METHANOL
Synonyms
2-Amino-5-hydroxymethyL;Abemaciclib Impurity 33;2-Amino-5-pyridinemethanol;2-AMinopyridine-5-Methanol;(6-aminopyridin-3-yl)metha;(6-Amino-3-pyridyl)methanol;2-Amino-5-hydroxymethylpy...;3-Pyridinemethanol, 6-amino-;(6-AMINO-3-PYRIDINYL)METHANOL;2-Aminopyridine-5-methanol,97%
CBNumber:
CB0176628
Molecular Formula:
C6H8N2O
Molecular Weight:
124.14
MDL Number:
MFCD06659089
MOL File:
113293-71-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 17:20:54
Product description Number Pack Size Price
2-Amino-5-pyridinemethanol MNO000168 1g $191
2-Amino-5-pyridinemethanol >98.0%(GC)(T) A3148 1g $100
2-Amino-5-pyridinemethanol NEA29371 10g $354
2-Amino-5-(hydroxymethyl)pyridine 97% OR14503 250mg $22
(6-Amino-3-pyridinyl)methanol 98% AS31879 1g $64
More product size

(6-AMINO-3-PYRIDINYL)METHANOL Properties

Melting point 120 °C
Boiling point 320.2±27.0 °C(Predicted)
Density 1.257±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
form powder to crystal
pka 13.61±0.10(Predicted)
color White to Light yellow to Light orange
Water Solubility Sparingly soluble in water.(0.26 g/L) (25°C),
InChI InChI=1S/C6H8N2O/c7-6-2-1-5(4-9)3-8-6/h1-3,9H,4H2,(H2,7,8)
InChIKey TXPRFSOGPYITOT-UHFFFAOYSA-N
SMILES C1=NC(N)=CC=C1CO
CAS DataBase Reference 113293-71-3
UNSPSC Code 12352200
NACRES NA.21

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335-H302
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi,Xn
Risk Statements  22-36/37/38-20/21/22
Safety Statements  22-26-36/37/39
RIDADR  2811
WGK Germany  WGK 3
Hazard Note  Irritant
HS Code  29221990
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
NFPA 704
1
2 0

(6-AMINO-3-PYRIDINYL)METHANOL price More Price(59)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich MNO000168 2-Amino-5-pyridinemethanol 113293-71-3 1g $191 2026-04-30 Buy
TCI Chemical A3148 2-Amino-5-pyridinemethanol >98.0%(GC)(T) 113293-71-3 1g $100 2026-04-30 Buy
Biosynth NEA29371 2-Amino-5-pyridinemethanol 113293-71-3 10g $354 2026-06-04 Buy
Apolloscientific OR14503 2-Amino-5-(hydroxymethyl)pyridine 97% 113293-71-3 250mg $22 2026-06-04 Buy
Activate Scientific AS31879 (6-Amino-3-pyridinyl)methanol 98% 113293-71-3 1g $64 2026-06-04 Buy
Product number Packaging Price Buy
MNO000168 1g $191 Buy
A3148 1g $100 Buy
NEA29371 10g $354 Buy
OR14503 250mg $22 Buy
AS31879 1g $64 Buy

(6-AMINO-3-PYRIDINYL)METHANOL Chemical Properties,Uses,Production

Chemical Properties

White to light yellow solid

Uses

It is used as pharmaceutical intermediate. Benzoylthiophenes are allosteric enhancers (AE) of agonist activity at the A1 adenosine receptor.

Synthesis

6-Aminonicotinic acid

3167-49-5

(6-AMINO-3-PYRIDINYL)METHANOL

113293-71-3

1. Concentrated sulfuric acid (0.95 mL, 17.2 mmol, 0.5 eq.) was slowly added to a solution of 6-aminonicotinic acid (5.0 g, 34.4 mmol) in ethanol (50 mL). 2. The reaction mixture was heated and refluxed for 16 h. 3. Upon completion of the reaction the mixture was carefully poured into a concentrated aqueous solution of Na2CO3 to neutralize. 4. The aqueous phases were extracted three times using EtOAc. 5. The organic layers were combined, washed with saturated brine, dried over anhydrous Na2SO4, filtered, and concentrated under reduced pressure.6 The concentrated residue was dissolved in anhydrous THF (25 mL).7 Lithium aluminium hydride (2.68 g, 68.6 mmol, 3.0 eq.) was added slowly at -60 °C.8 The reaction mixture was gradually warmed to 0 °C, followed by refluxing for 1 h. The reaction was completed by cooling to room temperature and then refluxing for 1 h. The reaction was completed by cooling to room temperature. At the end of the reaction, the reaction was cooled to room temperature and quenched by the addition of water (1.5 mL) and 5N aqueous NaOH (1.5 mL). 10. The precipitate was removed by filtration, and the filtrate was concentrated under reduced pressure. 11. The residue was purified by fast column chromatography (eluent: EtOAc/MeOH 95:5) to afford the target product, 6-amino-3-pyridinemethanol (2.15 g, 72% yield). 12. The structure of the product was determined by 1.5 mL of fast column chromatography (eluent: EtOAc/MeOH 95:5). The product structure was confirmed by 1H NMR and mass spectrometry: 1H NMR (400 MHz, d6-DMSO): δ= 7.82 (d, J = 1.7 Hz, 1H), 7.32 (dd, J = 8.3/2.5 Hz, 1H), 6.40 (dd, J = 9.3/1.0 Hz, 1H), 5.77 (br s, 2H), 4.88 ( t, J = 5.5 Hz), 4.88 (br s, 2H), 4.88 (t, J = 5.5 Hz, 4.88), 4.88 ( t, J = 5.5 Hz, 1H), 4.27 (d, J = 5.5 Hz, 2H). MS (ES+): 125 (M + H)+.

References

[1] Patent: WO2008/74752, 2008, A2. Location in patent: Page/Page column 27-28
[2] Patent: EP1798221, 2007, A1. Location in patent: Page/Page column 32
[3] Patent: EP1956013, 2008, A1. Location in patent: Page/Page column 30-31
[4] Patent: US2007/99930, 2007, A1. Location in patent: Page/Page column 42
[5] Patent: WO2013/13817, 2013, A1

Global( 179)Suppliers
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Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 20122 58
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View Lastest Price from (6-AMINO-3-PYRIDINYL)METHANOL manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(6-AMINO-3-PYRIDINYL)METHANOL pictures 2026-05-05 (6-AMINO-3-PYRIDINYL)METHANOL
113293-71-3
 $10.00-95.00 1KG 0.98 20 tons Zibo Hangyu Biotechnology Development Co., Ltd
(6-AMINO-3-PYRIDINYL)METHANOL pictures 2025-11-18 (6-AMINO-3-PYRIDINYL)METHANOL
113293-71-3
 $1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
(6-Amino-3-pyridinyl)methanol pictures 2025-09-25 (6-Amino-3-pyridinyl)methanol
113293-71-3
 $1.00-200.00 1KG 99% Henan Fengda Chemical Co., Ltd

(6-AMINO-3-PYRIDINYL)METHANOL Spectrum

2-Amino-5-(hydroxymethyl)pyridine 2-Amino-5-pyridinemethanol 6-AMINO-3-HYDROXYMETHYLPYRIDINE (6-AMINO-3-PYRIDINYL)METHANOL (6-AMINO-PYRIDIN-3-YL)-METHANOL 2-Amino-5-(hydroxymethyl)pyridine 97% 3-Pyridinemethanol,6-amino-(9CI) 2-AMINO-5-PYRIDINEMETHANOL(2-AMINO-5-HYDROXYMETHYLPYRIDINE) (6-Aminopyridin-3-yl)methanol ,97% 2-Amino-5-hydroxymethylpy... 2-AMinopyridine-5-Methanol (6-Aminopyridin-3-yl)methanol, 6-Aminonicotinyl alcohol 2-Amino-5-hydroxymethyL 3-Pyridinemethanol, 6-amino- 2-Aminopyridine-5-methanol,97% (6-AMINO-3-PYRIDINYL)METHANOL ISO 9001：2015 REACH (6-Amino-3-pyridyl)methanol (6-aminopyridin-3-yl)metha Abemaciclib Impurity 33 113293-71-3 Furans PYRIDINE pharmacetical
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