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ChemicalBook >> CAS DataBase List >>Alpha-D-Lactose monohydrate

Alpha-D-Lactose monohydrate

CAS No.
5989-81-1
Chemical Name:
Alpha-D-Lactose monohydrate
Synonyms
LACTOSE MONOHYDRATE;α-Lactose;α-Lactose monohydrate;ALPHA-LACTOSE MONOHYDRATE;α-D-Lactose monohydrate;MILK SUGAR;ALPHA-D-LACTOSE;Pharmatose 150M;LACTOSE MONOHYDRATE (ALPHA-FORM);A-LACTOSE
CBNumber:
CB0177832
Molecular Formula:
C12H24O12
Molecular Weight:
360.31
MDL Number:
MFCD00150747
MOL File:
5989-81-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 16:06:25
Product description Number Pack Size Price
α-Lactose monohydrate suitable for cell culture, BioReagent L2643 5kg $188
Lactose Monohydrate analyticalstandard 47287-U 1kit $27.8
a-Lactose monohydrate OL05009 2kg $176.52
a-Lactose monohydrate OL05009 5kg $363.45
a-Lactose monohydrate OL05009 10kg $687.9
More product size

Alpha-D-Lactose monohydrate Properties

Melting point 219 °C
Boiling point 412.35°C (rough estimate)
alpha [α]D20+52.2～+52.8°
Density 1,53 g/cm3
RTECS OD9625000
refractive index 1.6480 (estimate)
storage temp. Inert atmosphere,Room Temperature
solubility H2O: soluble1M, clear, colorless
form Solid
color White to Off-White
PH pH (50g/l, 25℃) : 4.0～6.0
biological source bovine milk
Water Solubility Soluble in water.
Stability Hygroscopic
InChI 1S/C12H22O11.H2O/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17;/h3-20H,1-2H2;1H2/t3-,4-,5+,6+,7-,8-,9-,10-,11+,12+;/m1./s1
InChIKey WSVLPVUVIUVCRA-KPKNDVKVSA-N
SMILES [H]O[H].OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O
CAS DataBase Reference 5989-81-1(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII EWQ57Q8I5X
EPA Substance Registry System .alpha.-D-Glucopyranose, 4-O-.beta.-D-galactopyranosyl-, hydrate (1:1) (5989-81-1)
UNSPSC Code 85151701
NACRES NA.75

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P301+P312-P302+P352-P304+P340-P305+P351+P338
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  Xi
Risk Statements  40-36/37/38
Safety Statements  24/25-36-26
WGK Germany  3
TSCA  Yes
HS Code  17021100
Storage Class 11 - Combustible Solids
NFPA 704
1
1 0

Alpha-D-Lactose monohydrate price More Price(44)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich L2643 α-Lactose monohydrate suitable for cell culture, BioReagent 5989-81-1 5kg $188 2026-04-30 Buy
Sigma-Aldrich 47287-U Lactose Monohydrate analyticalstandard 5989-81-1 1kit $27.8 2026-04-30 Buy
Biosynth OL05009 a-Lactose monohydrate 5989-81-1 2kg $176.52 2026-06-04 Buy
Biosynth OL05009 a-Lactose monohydrate 5989-81-1 5kg $363.45 2026-06-04 Buy
Biosynth OL05009 a-Lactose monohydrate 5989-81-1 10kg $687.9 2026-06-04 Buy
Product number Packaging Price Buy
L2643 5kg $188 Buy
47287-U 1kit $27.8 Buy
OL05009 2kg $176.52 Buy
OL05009 5kg $363.45 Buy
OL05009 10kg $687.9 Buy

Alpha-D-Lactose monohydrate Chemical Properties,Uses,Production

Chemical Properties

Lactose occurs as white to off-white crystalline particles or powder. It is odorless and slightly sweet-tasting. Spray-dried directcompression grades of lactose are generally composed of 80–90% specially prepared pure a-lactose monohydrate along with 10–20% of amorphous lactose.

Chemical Properties

White powder

Uses

alpha-D-Lactose monohydrate is used as a carrier and stabiliser of aromas, pharmaceutical products, Food industry.

Definition

A sugar that occurs in many plants. It is extracted commercially from sugar cane and sugar beet. Sucrose is a disaccharide formed from a glucose unit and a fructose unit. It is hydrolyzed to a mixture of fructose and glucose by the enzyme invertase. Since this mixture has a different optical rotation (levorotatory) than the original sucrose, the mixture is called invert sugar.

Production Methods

A suspension of a-lactose monohydrate crystals in a lactose solution is atomized and dried in a spray drier. Approximately 10–20% of the total amount of lactose is in solution and the remaining 80–90% is present in the crystalline form. The spray-drying process predominantly produces spherical particles. The compactibility of the material and its flow characteristics are a function of the primary particle size of the lactose monohydrate and the amount of amorphous lactose.

Pharmaceutical Applications

Spray-dried lactose is widely used as a binder, filler-binder, and flow aid in direct compression tableting.

Biochem/physiol Actions

alpha-Lactose is the primary sugar present in milk and the main energy source to a newborn mammalian through its mother′s milk. It is digested by the intestinal lactase (EC 3.2.1.108), an enzyme expressed in newborns. The enzyme′s activity declines following weaning which can lead to lactose intolerance in adult mammals.

Safety

Lactose is widely used in pharmaceutical formulations as a diluent in oral capsule and tablet formulations. It may also be used in intravenous injections.
Adverse reactions to lactose are largely due to lactose intolerance, which occurs in individuals with a deficiency of the enzyme lactase.

storage

Spray-dried lactose should be stored in a well-closed container in a cool, dry place.

Incompatibilities

Lactose is a reducing sugar. The amorphous lactose, which is the most reactive form of lactose present in spray-dried lactose, will interact more readily than conventional crystalline grades. Typical reactions include the Maillard reaction with either primary or secondary amines.

Alpha-D-Lactose monohydrate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 376)Suppliers
Supplier Tel Email Country ProdList Advantage
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19936 58
Hebei Chuanghai Biotechnology Co., Ltd 		+8615350571055 Sibel@chuanghaibio.com China 8738 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 20122 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29640 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21586 55
Shaanxi Pioneer Biotech Co., Ltd . 		+8613259417953 sales@pioneerbiotech.com China 1287 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29792 58
Hebei Runbin Biotechnology Co. LTD 		13180553332 2179877681@qq.com CHINA 990 58
Longyan Tianhua Biological Technology Co., Ltd 		0086 18039857276 18039857276 CHINA 2783 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58

View Lastest Price from Alpha-D-Lactose monohydrate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
α-Lactose monohydrate pictures 2026-06-12 α-Lactose monohydrate
5989-81-1
 25KG 98%-102% 20 tons WUHAN FORTUNA CHEMICAL CO., LTD
Alpha-D-Lactose monohydrate pictures 2026-03-20 Alpha-D-Lactose monohydrate
5989-81-1
 $10.00 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
D-Lactose monohydrate pictures 2025-12-16 D-Lactose monohydrate
10mg 99%+ HPLC 1000 Moxin Chemicals
alpha-D-Lactose Monohydrate, 99.5+%, 2-4% beta-isoMer alpha-D-Lactose Monohydrate, USP/NF, Ph.Eur., JP 250GR 4-O-beta-D-Galactopyranosyl-alpha-D-glucopyranose monohydrate LACTOSE MONOHYDRATE, a-(RG) Pharmatose 325 Pharmatose 50M Pharmatose DCL 11 Zeparox ^a-D-Lactose Monohydrate, 97%, 97% alpha-D(+)-La BETA-D-GAL-(1->4)-ALPHA-D-GLC BETA-D-GAL-(1->4)-ALPHA-D-GLC, MONOHYDRATE LACTOSE, A- D(+)-LACTOSE HYDRATE D-(+)-LACTOSE HYDRATE,ALPHA-FORM ALPHA-D(+)-LACTOBIOSE MONOHYDRATE ALPHA-D-(+)-LACTOSE, HYDRATE ALPHA-D(+)-LACTOSE MONOHYDRATE ALPHA-D-LACTOSE MONOHYDRATE A-LACTOBIOSE ALPHA-LACTOSE MONOHYDRATE, BIOXTRA ALPHA-LACTOSE MONOHYDRATE,>=99% (GC) β-D-Gal-(1→4)-α-D-Glc 4-O-β-D-Galactopyranosyl-α-D-glucose 4-O-BETA-D-GALACTOPYRANOSYL-ALPHA-D-GLUCOSE 4-O-BETA-D-GALACTOPYRANOSYL-ALPHA-D-GLUCOSE MONOHYDRATE D-LACTOSE MONOHYDRATE A.C.S. REAGENT A-LACTOSE MONOHYDRATE CELL CULTURE*TESTE D LACTOSE MONOHYDRATE 500MG NEAT A-LACTOSE MONOHYDRATE SIGMAULTRA Α-D-LACTOSE MONOHYDRATE GR ACS Α-D-LACTOSE MONOHYDRATE 99.5+% Α-D-LACTOSE MONOHYDRATE USP NF PH.EUR.,JP beta-D-Gal-[1.4]-alpha-D-Glc.H2O alpha-D-Lactose monohydrate, 99.5+% 4-O-beta-d-Galactopyranosyl 4-O-beta-d-Galactopyranosyl-d-glucose alpha-D-Glucopyranose, 4-O-beta-D-galactopyranosyl-, monohydrate Saccharum lactis alpha-D-Lactose monohydrate, USP/NF, Ph.Eur., JP alpha-D-Lactose, monohydrate, reagent ACS à-d-lactose monohydrate LACTOSE USP a-D-Lactose monohydrate β-D-Gal-(1-4)-α-D-Glc, Milk sugar, 4-O-β-D-Galactopyranosyl-α-D-glucose α-Lactose monohydrate, β-D-Gal-(1-4)-α-D-Glc, Milk sugar, 4-O-β-D-Galactopyranosyl-α-D-glucose α-Lactose monohydrate ,98% Lactose Monohydrate (500 mg) D -LACTOSE, ACS 4-O-β-D-Galactopyranosyl-α-D-glucose α-Lactose monohydrate, AR，≥98.0% (HPLC) 4-O-β-D-Galactopyranosyl-α-D-glucopyranose monohydrate (2S,3R,4R,5S,6R)-6-(hydroxymethyl)-5-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2,3,4-triol (2S,3R,4R,5S,6R)-6-(hydroxymethyl)-5-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2,3,4-triol hydrate Alpha-D-Lactose monohydrate USP/EP/BP Lactose / anhydrous lactose Inhalac 120 (contains β anomer) alpha-D-Lactose 1-hydrate O4-β-D-galactopyranosyl-β-D-glucopyranose hydrate
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