4-PHENOXYPHENYLACETIC ACID
- CAS No.
- 6328-74-1
- Chemical Name:
- 4-PHENOXYPHENYLACETIC ACID
- Synonyms
- 2-(4-PHENOXYPHENYL)ACETIC ACID;NSC 43857;RARECHEM AL BO 1521;4-PHENOXYPHENYLACETIC;4-PHENOXYPHENYLACETIC ACID;p-Phenoxyphenylacetic Acid;4-Phenoxybenzeneacetic Acid;p-Phenyloxyphenylacetic Acid;4-Phenoxyphenylethanoic acid;4-Phenoxyphenylacetic acid 97%
- CBNumber:
- CB0217297
- Molecular Formula:
- C14H12O3
- Molecular Weight:
- 228.24
- MDL Number:
- MFCD00079779
- MOL File:
- 6328-74-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 4-Phenoxyphenylacetic acid 97% | 665053 | 1g | $44 |
| 4-Phenoxyphenylacetic acid 97% | 665053 | 5g | $209 |
| 4-Phenoxyphenylacetic acid Asreported | 288185 | 2g | $353 |
| 4-Phenoxyphenylacetic acid Asreported | 288185 | 5g | $569 |
| 4-Phenoxyphenylacetic acid Asreported | 288185 | 10g | $789 |
| More product size | |||
| Melting point | 72-79 °C |
|---|---|
| Boiling point | 382℃ |
| Density | 1.217 |
| refractive index | 1.5800 (estimate) |
| Flash point | 146℃ |
| storage temp. | Sealed in dry,Room Temperature |
| form | solid |
| pka | 4.34±0.10(Predicted) |
| Appearance | White to off-white Solid |
| InChI | 1S/C14H12O3/c15-14(16)10-11-6-8-13(9-7-11)17-12-4-2-1-3-5-12/h1-9H,10H2,(H,15,16) |
| InChIKey | VARVNFDGRLLTCI-UHFFFAOYSA-N |
| SMILES | OC(=O)Cc1ccc(Oc2ccccc2)cc1 |
| CAS DataBase Reference | 6328-74-1(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS05,GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H317-H318-H410 | |||||||||
| Precautionary statements | P273-P280-P301+P312+P330-P302+P352-P305+P351+P338+P310 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves | |||||||||
| Hazard Codes | Xn,N,Xi | |||||||||
| Risk Statements | 22-50 | |||||||||
| Safety Statements | 60-61 | |||||||||
| RIDADR | UN 3077 9/PG 3 | |||||||||
| WGK Germany | 2 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29189900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Acute 1 Aquatic Chronic 1 Eye Dam. 1 Skin Sens. 1 |
|||||||||
| NFPA 704 |
|
4-PHENOXYPHENYLACETIC ACID price More Price(66)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 665053 | 4-Phenoxyphenylacetic acid 97% | 6328-74-1 | 1g | $44 | 2023-06-20 | Buy |
| Sigma-Aldrich | 665053 | 4-Phenoxyphenylacetic acid 97% | 6328-74-1 | 5g | $209 | 2023-06-20 | Buy |
| Usbiological | 288185 | 4-Phenoxyphenylacetic acid Asreported | 6328-74-1 | 2g | $353 | 2026-06-03 | Buy |
| Usbiological | 288185 | 4-Phenoxyphenylacetic acid Asreported | 6328-74-1 | 5g | $569 | 2026-06-03 | Buy |
| Usbiological | 288185 | 4-Phenoxyphenylacetic acid Asreported | 6328-74-1 | 10g | $789 | 2026-06-03 | Buy |
4-PHENOXYPHENYLACETIC ACID Chemical Properties,Uses,Production
Chemical Properties
White powder
Uses
4-PHENOXYPHENYLACETIC ACID is an arylaliphatic acid used in the preperation of protential inhibitors of collagen-induced aggregation of human thrombocytes. p-Phenyloxyphenylacetic Acid is a predicted metabolite of 6-Amino-4-(4-phenoxyphenylethylamino)quinazoline.
Uses
p-Phenyloxyphenylacetic Acid is an arylaliphatic acid used in the preperation of protential inhibitors of collagen-induced aggregation of human thrombocytes. p-Phenyloxyphenylacetic Acid is a predicted metabolite of 6-Amino-4-(4-phenoxyphenylethylamino)quinazoline (A621350).
Synthesis
4664-61-3
6328-74-1
General procedure for the synthesis of 4-phenoxyphenylacetic acid from methyl 2-(4-phenoxyphenyl)acetate: 1N aqueous NaOH solution (7.8 mL) was added to a solution of methyl 4-phenoxyphenylacetate (948 mg, 3.9 mmol) in ethanol (20 mL), and the reaction was stirred at room temperature for 5 hours. After completion of the reaction, the reaction solution was concentrated under reduced pressure and acidified by adding 1N aqueous hydrochloric acid (10 mL). The precipitated white solid was collected by filtration and washed with water and ether sequentially to afford 4-phenoxyphenylacetic acid (813 mg, 91% yield) as a white solid. The product was detected by LC-MS showing m/z 229 [M + H]+, and 1H-NMR (300 MHz, CDCl3) data were as follows: δ 6.91-7.01 (m, 4H), 7.10-7.14 (t, J = 6.6 Hz, 1H), 7.25-7.28 (d, J = 8.4 Hz, 2H), 7.35-7.41 (m, 2H) .
References
[1] Patent: EP1849465, 2007, A1. Location in patent: Page/Page column 139
[2] Chemical and pharmaceutical bulletin, 1965, vol. 13, # 11, p. 1341 - 1345
[3] Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 13, p. 3695 - 3700
4-PHENOXYPHENYLACETIC ACID Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569262 +86-15003564040 | 1056@dideu.com | China | 3970 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10000 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14304 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
| Aromsyn Co., Ltd. | +86-0571-85585865 +8613336024896 | CB@aromsyn.com | China | 19183 | 58 |
View Lastest Price from 4-PHENOXYPHENYLACETIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-08-12 | 4-PHENOXYPHENYLACETIC ACID
6328-74-1
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2019-07-06 | 4-PHENOXYPHENYLACETIC ACID
6328-74-1
|
$7.00 | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- 4-PHENOXYPHENYLACETIC ACID
6328-74-1
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 4-PHENOXYPHENYLACETIC ACID
6328-74-1
- $7.00
- 99%
- Career Henan Chemical Co
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