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ChemicalBook >> CAS DataBase List >>2-Iodo-4,5-Difluoroaniline

2-Iodo-4,5-Difluoroaniline

CAS No.
847685-01-2
Chemical Name:
2-Iodo-4,5-Difluoroaniline
Synonyms
4,5-Difluoro-2-iodoaniline;2-Iodo-4,5-Difluoroaniline;4,5-Difluoro-2-iodoaniline, 97%;BenzenaMine, 4,5-difluoro-2-iodo-;2-Iodo-4,5-Difluoroaniline ISO 9001:2015 REACH;2-Iodo-4,5-Difluoroaniline 4,5-Difluoro-2-iodoaniline
CBNumber:
CB02552226
Molecular Formula:
C6H4F2IN
Molecular Weight:
255
MDL Number:
MFCD03095321
MOL File:
847685-01-2.mol
Last updated:2026-05-27 17:25:11
Product description Number Pack Size Price
4,5-Difluoro-2-iodoaniline 97% PC907253 1g $36
4,5-Difluoro-2-iodoaniline 97% PC907253 5g $92
4,5-Difluoro-2-iodoaniline 97% PC907253 25g $429
4,5-Difluoro-2-iodoaniline 97% PC907253 100g $1703
4,5-Difluoro-2-iodoaniline 97% PC907253 1g $36
More product size

2-Iodo-4,5-Difluoroaniline Properties

Boiling point 258℃
Density 2.086
Flash point 110℃
storage temp. 2-8°C(protect from light)
Appearance Brown to reddish brown Liquid
InChI InChI=1S/C6H4F2IN/c7-3-1-5(9)6(10)2-4(3)8/h1-2H,10H2
InChIKey XBOMEOMTVVEEDW-UHFFFAOYSA-N
SMILES C1(N)=CC(F)=C(F)C=C1I

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2921420090

2-Iodo-4,5-Difluoroaniline price More Price(50)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific PC907253 4,5-Difluoro-2-iodoaniline 97% 847685-01-2 1g $36 2026-06-04 Buy
Apolloscientific PC907253 4,5-Difluoro-2-iodoaniline 97% 847685-01-2 5g $92 2026-06-04 Buy
Apolloscientific PC907253 4,5-Difluoro-2-iodoaniline 97% 847685-01-2 25g $429 2026-06-04 Buy
Apolloscientific PC907253 4,5-Difluoro-2-iodoaniline 97% 847685-01-2 100g $1703 2026-06-04 Buy
Apolloscientific PC907253 4,5-Difluoro-2-iodoaniline 97% 847685-01-2 1g $36 2026-06-04 Buy
Product number Packaging Price Buy
PC907253 1g $36 Buy
PC907253 5g $92 Buy
PC907253 25g $429 Buy
PC907253 100g $1703 Buy
PC907253 1g $36 Buy

2-Iodo-4,5-Difluoroaniline Chemical Properties,Uses,Production

Chemical Properties

Colorless Liquid

Synthesis

3,4-Difluoroaniline

3863-11-4

2-Iodo-4,5-Difluoroaniline

847685-01-2

The general procedure for the synthesis of 2-iodo-4,5-difluoroaniline using 3,4-difluoroaniline as starting material was as follows: 3,4-difluoroaniline (645 mg, 5 mmol) was suspended in distilled water (25 mL). Sodium bicarbonate (630 mg, 7.5 mmol) was then added, followed by iodine monomer (1.65 g, 6.5 mmol). The reaction mixture was stirred vigorously at room temperature (~25°C) for 30 minutes. Upon completion of the reaction, the mixture was poured into saturated sodium thiosulfate solution (50 mL) to quench the reaction. Extraction was carried out with ethyl acetate (2 x 25 mL) and the organic phases were combined. The organic phase was washed sequentially with sodium thiosulfate solution (20 mL), distilled water (20 mL) and saturated saline (20 mL) to remove unreacted iodine and other water-soluble impurities. The washed organic phase was dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to afford 2-iodo-4,5-difluoroaniline as a dark colored oil (1.24 g, 97% yield).

References

[1] Patent: WO2006/82400, 2006, A1. Location in patent: Page/Page column 55
[2] Tetrahedron Letters, 2005, vol. 46, # 6, p. 907 - 910
[3] Organic Letters, 2008, vol. 10, # 13, p. 2657 - 2659
[4] Patent: EP2141164, 2010, A1. Location in patent: Page/Page column 44
[5] Journal of Fluorine Chemistry, 2012, vol. 135, p. 97 - 107

2-Iodo-4,5-Difluoroaniline Preparation Products And Raw materials

Global( 74)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29640 60
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768 52513593@qq.com CHINA 2972 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49979 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29792 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-87569262 +86-15003564040 1056@dideu.com China 3970 58
Fuxin Pharmaceutical
+86-021-021-50872116 +8613122107989 contact@fuxinpharm.com China 10000 58
Win-Win chemical CO., Limited
+86-0086-577-64498589 +86-15355981851 sales@win-winchemical.com China 14304 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418684 +8618949823763 sales@tnjchem.com China 25356 58
Aromsyn Co., Ltd.
+86-0571-85585865 +8613336024896 CB@aromsyn.com China 19183 58

View Lastest Price from 2-Iodo-4,5-Difluoroaniline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Iodo-4,5-Difluoroaniline pictures 2026-02-02 2-Iodo-4,5-Difluoroaniline
847685-01-2
10mg 99%HPLC 2000tons Shaanxi Dideu Medichem Co. Ltd
4,5-Difluoro-2-iodoaniline pictures 2020-01-09 4,5-Difluoro-2-iodoaniline
847685-01-2
$1.00 1KG Min98% HPLC Career Henan Chemical Co

2-Iodo-4,5-Difluoroaniline Spectrum

2-Iodo-4,5-Difluoroaniline 2-Iodo-4,5-Difluoroaniline 4,5-Difluoro-2-iodoaniline BenzenaMine, 4,5-difluoro-2-iodo- 2-Iodo-4,5-Difluoroaniline ISO 9001:2015 REACH 4,5-Difluoro-2-iodoaniline 4,5-Difluoro-2-iodoaniline, 97% 847685-01-2
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