3-b]pyridine
![3-b]pyridine Structure](CAS/20180713/GIF/1357945-27-7.gif)
- CAS No.
- 1357945-27-7
- Chemical Name:
- 3-b]pyridine
- Synonyms
- o[4,3-b]pyridine;oro-3-iodo-1H-pyrazoL;5-chloro-3-iodo-1H-pyrazolo[4;5-Chloro-3-iodo-1H-pyrazolo[4,3-b]pyridine;1H-Pyrazolo[4,3-b]pyridine, 5-chloro-3-iodo-
- CBNumber:
- CB02616504
- Molecular Formula:
- C6H3ClIN3
- Molecular Weight:
- 279.47
- MDL Number:
- MFCD16658104
- MOL File:
- 1357945-27-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 5-chloro-3-iodo-1H-pyrazolo[4,3-b]pyridine | 189033 | 500.00mg | $526 |
| 5-chloro-3-iodo-1H-pyrazolo[4,3-b]pyridine | 189033 | 1.00g | $766 |
| 5-chloro-3-iodo-1H-pyrazolo[4,3-b]pyridine | 189033 | 5.00g | $2296 |
| 5-Chloro-3-iodo-1H-pyrazolo[4,3-b]pyridine 97% | AA009HJU | 100mg | $5 |
| 5-Chloro-3-iodo-1H-pyrazolo[4,3-b]pyridine 97% | AA009HJU | 250mg | $8 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H320-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
3-b]pyridine price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 189033 | 5-chloro-3-iodo-1H-pyrazolo[4,3-b]pyridine | 1357945-27-7 | 500.00mg | $526 | 2026-05-18 | Buy |
| Matrix Scientific | 189033 | 5-chloro-3-iodo-1H-pyrazolo[4,3-b]pyridine | 1357945-27-7 | 1.00g | $766 | 2026-05-18 | Buy |
| Matrix Scientific | 189033 | 5-chloro-3-iodo-1H-pyrazolo[4,3-b]pyridine | 1357945-27-7 | 5.00g | $2296 | 2026-05-18 | Buy |
| aablocks | AA009HJU | 5-Chloro-3-iodo-1H-pyrazolo[4,3-b]pyridine 97% | 1357945-27-7 | 100mg | $5 | 2026-05-28 | Buy |
| aablocks | AA009HJU | 5-Chloro-3-iodo-1H-pyrazolo[4,3-b]pyridine 97% | 1357945-27-7 | 250mg | $8 | 2026-05-28 | Buy |
3-b]pyridine Chemical Properties,Uses,Production
Uses
5-Chloro-3-iodo-1H-pyrazolo[4,3-b]pyridine is a reactant used for the synthesis of Benzothiazol-6-ylacetic acid derivatives as anti-HIV.
Synthesis
![5-Chloro-1H-pyrazolo[4,3-b]pyridine](/CAS/GIF/94220-45-8.gif)
94220-45-8
![3-b]pyridine](/CAS/20180713/GIF/1357945-27-7.gif)
1357945-27-7
To a solution of 5-chloro-1H-pyrazolo[4,3-b]pyridine (XIII) (13 g, 84.7 mmol) in N,N-dimethylformamide (DMF) (100 mL) was added iodine (43.0 g, 169 mmol), followed by batchwise addition of potassium hydroxide powder (23.75 g, 423 mmol), and the reaction mixture was cooled in an ice water bath. The reaction mixture was stirred at 25 °C overnight. The solid potassium hydroxide was removed by filtration and the filter cake was washed with ethyl acetate (EtOAc). Most of the DMF was evaporated under reduced pressure and the residue was diluted with water (200 mL) and extracted with ethyl acetate (5 × 200 mL). The organic phases were combined, washed with saturated saline (500 mL) and dried over anhydrous sodium sulfate (Na2SO4). The organic phases were concentrated to afford 5-chloro-3-iodo-1H-pyrazolo[4,3-b]pyridine (XIV) as an orange solid (23.5 g, 84.1 mmol, 99.3% yield). The m/z of C6H3ClIN3 was measured to be 279.9 ([M+H]+) by electrospray ionization mass spectrometry (ESIMS).
References
[1] Patent: WO2017/23989, 2017, A1. Location in patent: Paragraph 0606; 0607
[2] Patent: WO2017/23972, 2017, A1. Location in patent: Paragraph 0606; 0607
[3] Patent: WO2017/24015, 2017, A1. Location in patent: Paragraph 006
[4] Patent: WO2017/23988, 2017, A1. Location in patent: Paragraph 0607
[5] Patent: WO2017/220431, 2017, A1. Location in patent: Page/Page column 36; 37
3-b]pyridine Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| Xuzhou B&C Chemical Technology Co., Ltd | +86-400-0516-021 +8617855106283 | info@bcpharma.com | China | 2732 | 58 |
| Zhengzhou Anbu Chem Co.,Ltd | +86-0371-88006763; +8615988602810 | sales@anbuchem.com | China | 3016 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20122 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39927 | 58 |
View Lastest Price from 3-b]pyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![3-b]pyridine pictures](https://img.chemicalbook.com/ProductImageEN/2018-8/Small/fecf371d-b0ef-4cc9-b662-2be5de85f9f1.png) |
2019-07-06 | 3-b]pyridine
1357945-27-7
|
$1.00 | 1KG | 95% | 500kg | Career Henan Chemical Co |
-
- 3-b]pyridine
1357945-27-7
- $1.00
- 95%
- Career Henan Chemical Co
