CPhos
- CAS No.
- 1160556-64-8
- Chemical Name:
- CPhos
- Synonyms
- Cphos;2-Dicyclohexylphosphino-2',6'-bis(dimethylamino)-1,1'-biphenyl;2-(Dicyanomethylen)indan;phosphino-2',6'-bis(N,N-dimethyL;2’-(Dicyclohexylphosphino)-2,6-di(dimethylamino)biphenyl;2-DICYCLOHEXYLPHOSPHINO-2',6'-DIMETHYLAMINO-1,1'-BIPHENYL;2-Dicyclohexylphosphino-2',6'-bis(N,N-dimethylamino)biphenyl;2-Dicyclohexylphosphino-2',6'-bis(diMethylaMino)-1,1'-bipheny;2'-(Dicyclohexylphosphino)-N2,N2,N6,N6-tetramethyl[1,1'-biphen;2'-(dicyclohexylphosphino)-N2,N2,N6,N6-tetramethylbiphenyl-2...
- CBNumber:
- CB02709536
- Molecular Formula:
- C28H41N2P
- Molecular Weight:
- 436.61
- MDL Number:
- MFCD27978504
- MOL File:
- 1160556-64-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| CPhos 98% | 759171 | 1g | $191 |
| CPhos 98% | 759171 | 5g | $624 |
| 2-Dicyclohexylphosphino-2',6'-bis(dimethylamino)-1,1'-biphenyl, min. 98% CPhos min.98% | 15-1147 | 250mg | $56 |
| 2-Dicyclohexylphosphino-2',6'-bis(dimethylamino)-1,1'-biphenyl, min. 98% CPhos min.98% | 15-1147 | 1g | $162 |
| 2-Dicyclohexylphosphino-2',6'-bis(dimethylamino)-1,1'-biphenyl, min. 98% CPhos min.98% | 15-1147 | 5g | $624 |
| More product size | |||
| Melting point | 111-113°C |
|---|---|
| Boiling point | 592.8±50.0 °C(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 5.04±0.28(Predicted) |
| form | crystal |
| color | yellow-orange |
| InChI | InChI=1S/C28H41N2P/c1-29(2)25-19-13-20-26(30(3)4)28(25)24-18-11-12-21-27(24)31(22-14-7-5-8-15-22)23-16-9-6-10-17-23/h11-13,18-23H,5-10,14-17H2,1-4H3 |
| InChIKey | DRNAQRXLOSUHBQ-UHFFFAOYSA-N |
| SMILES | C1(C2=CC=CC=C2P(C2CCCCC2)C2CCCCC2)=C(N(C)C)C=CC=C1N(C)C |
| CAS DataBase Reference | 1160556-64-8 |
| FDA UNII | 9D5DWS5PBX |
| UNSPSC Code | 12352116 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| target organs | Respiratory system |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26 |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
CPhos price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 759171 | CPhos 98% | 1160556-64-8 | 1g | $191 | 2026-04-30 | Buy |
| Sigma-Aldrich | 759171 | CPhos 98% | 1160556-64-8 | 5g | $624 | 2023-06-20 | Buy |
| Strem Chemicals | 15-1147 | 2-Dicyclohexylphosphino-2',6'-bis(dimethylamino)-1,1'-biphenyl, min. 98% CPhos min.98% | 1160556-64-8 | 250mg | $56 | 2026-04-30 | Buy |
| Strem Chemicals | 15-1147 | 2-Dicyclohexylphosphino-2',6'-bis(dimethylamino)-1,1'-biphenyl, min. 98% CPhos min.98% | 1160556-64-8 | 1g | $162 | 2026-04-30 | Buy |
| Strem Chemicals | 15-1147 | 2-Dicyclohexylphosphino-2',6'-bis(dimethylamino)-1,1'-biphenyl, min. 98% CPhos min.98% | 1160556-64-8 | 5g | $624 | 2026-04-30 | Buy |
CPhos Chemical Properties,Uses,Production
Reactions
Preparation of aryl sulfonamides via palladium-catalyzed chlorosulfonylation of arylboronic acids.
Description
CPhos, the full name of which is 2'-(Dicyclohexylphosphino)-N2,N2,N6,N6-tetramethyl(1,1'-biphenyl)-2,6-diamine, is a highly efficient palladium catalyst with excellent cross-coupling activity and is widely used in organic synthesis and materials science.
Uses
CPhos, is used as a catalyst in the synthetic preparation of palladium-catalyzed Negishi coupling of secondary alkylzinc halides with aryl bromides and chlorides.
Uses
CPhos can be used:
- As a ligand in the Pd-catalyzed synthesis of 3-cyclopentylindole derivatives, dihydrobenzofurans and trans-bicyclic sulfamides.
- To synthesize palladacycle precatalysts for Negishi coupling of secondary alkylzinc.
reaction suitability
reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: ligand
reaction type: Cross Couplings



CPhos Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Honest Joy Holdings Limited | +86-0755-36694831 13717124449 | sales@debayer.com | China | 300 | 58 |
| XINXIANG RUNYU MATERIAL CO., LTD. | +86-13592593621; +86-16627710726 | sales@runvmat.com | China | 462 | 58 |
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-15225627621 +86-13213167925 | jiuyitime@fdachem.com | China | 16511 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14026 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 +86-18019713315 | info@accelachem.com | United States | 21193 | 58 |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29792 | 58 |
| Richest Group Ltd | 18017061086 | oled@richest-group.com | CHINA | 5600 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 | contact@trustwe.com | China | 5746 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1059@dideu.com | China | 29093 | 58 |
View Lastest Price from CPhos manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![]() |
2026-08-01 | 2-Dicyclohexylphosphino-2',6'-bis(diMethylaMino)-1,1'-biphenyl
1160556-64-8
|
1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
![]() |
2026-07-02 | 2-Dicyclohexylphosphino-2',6'-bis(diMethylaMino)-1,1'-biphenyl, Min. 98% Cphos
1160556-64-8
|
$2.00-5.00 | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
![]() |
2019-12-23 | 2-Dicyclohexylphosphino-2',6'-bis(N,N-dimethylamino)biphenyl
1160556-64-8
|
$2.00 | 1KG | ≥98% | 100kg | Career Henan Chemical Co |
-

- 2-Dicyclohexylphosphino-2',6'-bis(diMethylaMino)-1,1'-biphenyl
1160556-64-8
- $0.00
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-

- 2-Dicyclohexylphosphino-2',6'-bis(diMethylaMino)-1,1'-biphenyl, Min. 98% Cphos
1160556-64-8
- $2.00-5.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-

- 2-Dicyclohexylphosphino-2',6'-bis(N,N-dimethylamino)biphenyl
1160556-64-8
- $2.00
- ≥98%
- Career Henan Chemical Co
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