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ChemicalBook >> CAS DataBase List >>(R)-(-)-(2-Methylacryloyl)-2,10-camphorsultam

(R)-(-)-(2-Methylacryloyl)-2,10-camphorsultam

CAS No.
116195-15-4
Chemical Name:
(R)-(-)-(2-Methylacryloyl)-2,10-camphorsultam
Synonyms
(R)-(-)-(2-Methylacryloyl)-2,10-camphorsultam;2-Propen-1-one, 2-methyl-1-[(3aS,6R,7aR)-tetrahydro-8,8-dimethyl-2,2-dioxido-3H-3a,6-methano-2,1-benzisothiazol-1(4H)-yl]-
CBNumber:
CB03161933
Molecular Formula:
C14H21NO3S
Molecular Weight:
283.39
MDL Number:
MOL File:
116195-15-4.mol
MSDS File:
SDS
Last updated:2026-05-27 17:40:04
Product description Number Pack Size Price
(R)-(-)-(2-Methylacryloyl)-2,10-camphorsultam 97% AA01EN3V 250mg $52
(R)-(-)-(2-Methylacryloyl)-2,10-camphorsultam 97% AA01EN3V 1g $124
(R)-(-)-(2-Methylacryloyl)-2,10-camphorsultam 97% CD11343342 250mg $55
1-((3aS,6R,7aR)-8,8-Dimethyl-2,2-dioxidohexahydro-1H-3a,6-methanobenzo[c]isothiazol-1-yl)-2-methylprop-2-en-1-one 97% CM247929 1g $86
1-((3aS,6R,7aR)-8,8-Dimethyl-2,2-dioxidohexahydro-1H-3a,6-methanobenzo[c]isothiazol-1-yl)-2-methylprop-2-en-1-one 97% CM247929 1g $86

(R)-(-)-(2-Methylacryloyl)-2,10-camphorsultam Properties

Melting point 145 °C
Boiling point 397.5±25.0 °C(Predicted)
Density 1.26±0.1 g/cm3(Predicted)
storage temp. 2-8°C
pka -14.95±0.40(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

(R)-(-)-(2-Methylacryloyl)-2,10-camphorsultam price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
aablocks AA01EN3V (R)-(-)-(2-Methylacryloyl)-2,10-camphorsultam 97% 116195-15-4 250mg $52 2026-05-30 Buy
aablocks AA01EN3V (R)-(-)-(2-Methylacryloyl)-2,10-camphorsultam 97% 116195-15-4 1g $124 2026-05-30 Buy
Crysdot CD11343342 (R)-(-)-(2-Methylacryloyl)-2,10-camphorsultam 97% 116195-15-4 250mg $55 2026-05-27 Buy
Chemenu CM247929 1-((3aS,6R,7aR)-8,8-Dimethyl-2,2-dioxidohexahydro-1H-3a,6-methanobenzo[c]isothiazol-1-yl)-2-methylprop-2-en-1-one 97% 116195-15-4 1g $86 2026-05-26 Buy
Chemenu CM247929 1-((3aS,6R,7aR)-8,8-Dimethyl-2,2-dioxidohexahydro-1H-3a,6-methanobenzo[c]isothiazol-1-yl)-2-methylprop-2-en-1-one 97% 116195-15-4 1g $86 2026-05-20 Buy
Product number Packaging Price Buy
AA01EN3V 250mg $52 Buy
AA01EN3V 1g $124 Buy
CD11343342 250mg $55 Buy
CM247929 1g $86 Buy
CM247929 1g $86 Buy

(R)-(-)-(2-Methylacryloyl)-2,10-camphorsultam Chemical Properties,Uses,Production

Synthesis

(2R)-Bornane-10,2-sultam

94594-90-8

Methacryloyl chloride

920-46-7

(R)-(-)-(2-Methylacryloyl)-2,10-camphorsultam

116195-15-4

Example 2: Synthesis of (R)-5-methyl-4,5-dihydro-pyrazole-1,5-dicarboxylic acid 1-[(4-chloro-phenyl)-amido]5-{[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenyl]-amido} Step 1. Synthesis of (3aS,6R,7aR)-1-methacryloyl-8,8-dimethylhexahydro-3a,6-methylene-2,1-benzisothiazole-2,2-dioxide (1S)-(-)-2,10-camphorsulfonate To a solution of (1S)-(-)-2,10-camphorsulfonamide (1.160 g, 5.388 mmol) in toluene (10 ml) was added sodium hydride (60% oil, 0.323 g, 8.08 mmol). After stirring for 1.5 h, methacryloyl chloride (1.126 g, 10.78 mmol) was added directly to the reaction mixture. The mixture was stirred overnight at room temperature, followed by evaporation of the solvent. The residue was extracted into ethyl acetate, washed with 1N HCl, dried with MgSO4, evaporated in vacuum and purified by chromatography (0-20% EtOAc in hexane solution) to afford the target compound (1.240 g, 81%). 1H NMR (400MHz, DMSO-D6) δ ppm: 0.90 (s, 3H), 1.08 (s, 3H), 1.23 (m, 1H), 1.42 (m, 1H), 1.78 (m, 5H), 1.81 (m, 3H), 3.26 (s, 4H), 3.56 (d, J = 14.04Hz, 1H), 3.77 (d , J = 14.04Hz, 1H), 3.91 (m, 1H), 5.48 (s, 1H), 5.60 (s, 1H).

References

[1] Journal of Organic Chemistry, 2008, vol. 73, # 8, p. 3218 - 3227
[2] Patent: WO2008/65503, 2008, A1. Location in patent: Page/Page column 36
[3] Tetrahedron Asymmetry, 1991, vol. 2, # 12, p. 1359 - 1370

(R)-(-)-(2-Methylacryloyl)-2,10-camphorsultam Preparation Products And Raw materials

(R)-(-)-(2-Methylacryloyl)-2,10-camphorsultam Suppliers

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View Lastest Price from (R)-(-)-(2-Methylacryloyl)-2,10-camphorsultam manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
((R)-(-)-(2-Methylacryloyl)-2,10-camphorsultam pictures 2019-12-23 ((R)-(-)-(2-Methylacryloyl)-2,10-camphorsultam
116195-15-4
$1.00 1KG 98% HPLC 10t Career Henan Chemical Co
(R)-(-)-(2-Methylacryloyl)-2,10-camphorsultam 2-Propen-1-one, 2-methyl-1-[(3aS,6R,7aR)-tetrahydro-8,8-dimethyl-2,2-dioxido-3H-3a,6-methano-2,1-benzisothiazol-1(4H)-yl]- 116195-15-4
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