BAFILOMYCIN C1
- CAS No.
- 88979-61-7
- Chemical Name:
- BAFILOMYCIN C1
- Synonyms
- L-681110A1;BAFILOMYCIN C1;Antibiotic L-681110A1;Bafilomycin C-1,Bafilomycin C1;2-Demethyl-2-methoxy-24-methylhygrolidin;Bafilomycin C1, from Streptomyces griseus;Bafilomycin C1, Vacuolar-type H+-ATPase inhibitor.;2-Butenedioic acid (2E)-, 1-[(2R,4R,5S,6R)-tetrahydro-2-hydroxy-2-[(1S,2R,3S)-2-hydroxy-3-[(2R,3S,4E,6E,9S,10S,11R,12E,14Z)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxooxacyclohexadeca-4,6,12,14-tetraen-2-yl]-1-methylbutyl]-5-methyl-6-(1-methylethyl)-2H-pyran-4-yl] ester
- CBNumber:
- CB0320023
- Molecular Formula:
- C39H60O12
- Molecular Weight:
- 720.89
- MDL Number:
- MFCD00904461
- MOL File:
- 88979-61-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Bafilomycin C1 ≥95% | 19625 | 1mg | $90 |
| Bafilomycin C1 ≥95% | 19625 | 5mg | $422 |
| Bafilomycin C1 ≥95% | 19625 | 1mg | $81 |
| Bafilomycin C1 ≥95% | 19625 | 5mg | $383 |
| Bafilomycin C1 (Antibiotic L-681,110A1) ~95%(HPLC) | B0003-72 | 1mg | $426 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| NFPA 704 |
|
BAFILOMYCIN C1 price More Price(26)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 19625 | Bafilomycin C1 ≥95% | 88979-61-7 | 1mg | $90 | 2026-04-30 | Buy |
| Cayman Chemical | 19625 | Bafilomycin C1 ≥95% | 88979-61-7 | 5mg | $422 | 2026-04-30 | Buy |
| Cayman Chemical | 19625 | Bafilomycin C1 ≥95% | 88979-61-7 | 1mg | $81 | 2024-03-01 | Buy |
| Cayman Chemical | 19625 | Bafilomycin C1 ≥95% | 88979-61-7 | 5mg | $383 | 2024-03-01 | Buy |
| Usbiological | B0003-72 | Bafilomycin C1 (Antibiotic L-681,110A1) ~95%(HPLC) | 88979-61-7 | 1mg | $426 | 2026-06-03 | Buy |
BAFILOMYCIN C1 Chemical Properties,Uses,Production
Uses
Bafilomycin C1 is a selective, reversible inhibitor of vacuolar H+-ATPases (V-ATPases). It blocks these pumps in mammalian, plant, or fungal cells, preventing proton transport and compartment acidification. Bafilomycin C1 has been shown to have angiostatic activity in the chick chorioallantoic membrane assay. It has also been used, when coupled to cellulose, to purify V-ATPases.[Cayman Chemical]
Uses
Bafilomycin C1 is a member of a potent family of macrocyclic lactones. Bafilomycin C1 shares a similar mode of action and activity as its more accessible A1 analogue. Bafilomycin C1 is broadly active against bacteria, fungi, insects, nematodes and cestodes. Bafilomycin C1 has attracted interest as a potential agent for treating osteoporosis. The presence of the fumarate group provides an ideal ligand for affinity chromatography of V-ATPase.
in vivo
Bafilomycin C1 (subcutaneous injection; 0.2 mg/kg; 20 days) retards the tumor growth without apparent adverse reactions or side effects in nude mice model[1].
| Animal Model: | BALB/c nude mice (weighing 18-20 g) subcutaneous injected by SMMC7721 cell suspension (5×106 cells/100 μL)[2] |
| Dosage: | 0.2 mg/kg |
| Administration: | Subcutaneous injection; 20 days |
| Result: | Suppressed tumor growth of SMMC7721 tumor xenografts. |
IC 50
Macrolide
storage
+4°C
BAFILOMYCIN C1 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53803 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9804 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 | psaitong@jm-bio.com | China | 12306 | 58 |
| Lynnchem | 86-(0)29-85992781 17792393971 | info@lynnchem.com | China | 4587 | 58 |
| Novachemistry | 44-20819178-90 02081917890 | info@novachemistry.com | United Kingdom | 4381 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 +86-13028896684; | sales@rrkchem.com | China | 57422 | 58 |
| Hefei fuya biotechnology co. LTD | 18096409024 | sales02@foreversyn.com | China | 1932 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
View Lastest Price from BAFILOMYCIN C1 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-12-22 | Bafilomycin C1
88979-61-7
|
10g | TargetMol Chemicals Inc. |
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- Bafilomycin C1
88979-61-7
- TargetMol Chemicals Inc.
