5-Bromo-2-fluoropyridine
- CAS No.
- 766-11-0
- Chemical Name:
- 5-Bromo-2-fluoropyridine
- Synonyms
- 5-BROMO-2-FLUOROPYRIDINE;5-Brom-2-fluorpyridin;3-BROMO-6-FLUOROPYRIDINE;5-BROMO-2-FLUO;2-Fluoro-5-bromopyri;2-FLUORO-5-BORMOPYRIDINE;3-fluoro-5-bromopyridine;2-Floro-5-Bromo Pyridine;2-FLUORO-5-BROMO PYRIDINE;5-Bromo-2-fluoropyridine>
- CBNumber:
- CB0344067
- Molecular Formula:
- C5H3BrFN
- Molecular Weight:
- 175.99
- MDL Number:
- MFCD01863742
- MOL File:
- 766-11-0.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 5-Bromo-2-fluoropyridine 99% | 520438 | 5g | $34.3 |
| 5-Bromo-2-fluoropyridine >98.0%(GC) | B2705 | 5g | $58 |
| 5-Bromo-2-fluoropyridine >98.0%(GC) | B2705 | 25g | $192 |
| 5-Bromo-2-fluoropyridine Asreported | 261712 | 50g | $333 |
| 5-Bromo-2-fluoropyridine Asreported | 261712 | 100g | $446 |
| More product size | |||
| Boiling point | 162-164 °C750 mm Hg(lit.) |
|---|---|
| Density | 1.71 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | 165 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | -2.79±0.10(Predicted) |
| form | Liquid |
| color | Clear colorless yellow |
| Specific Gravity | 1.710 |
| BRN | 1363171 |
| InChI | InChI=1S/C5H3BrFN/c6-4-1-2-5(7)8-3-4/h1-3H |
| InChIKey | MYUQKYGWKHTRPG-UHFFFAOYSA-N |
| SMILES | C1(F)=NC=C(Br)C=C1 |
| CAS DataBase Reference | 766-11-0(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-22 | |||||||||
| Safety Statements | 26-36/37-37/39 | |||||||||
| RIDADR | UN2810 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29339900 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
5-Bromo-2-fluoropyridine price More Price(108)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 520438 | 5-Bromo-2-fluoropyridine 99% | 766-11-0 | 5g | $34.3 | 2026-04-30 | Buy |
| TCI Chemical | B2705 | 5-Bromo-2-fluoropyridine >98.0%(GC) | 766-11-0 | 5g | $58 | 2026-04-30 | Buy |
| TCI Chemical | B2705 | 5-Bromo-2-fluoropyridine >98.0%(GC) | 766-11-0 | 25g | $192 | 2026-04-30 | Buy |
| Usbiological | 261712 | 5-Bromo-2-fluoropyridine Asreported | 766-11-0 | 50g | $333 | 2026-06-03 | Buy |
| Usbiological | 261712 | 5-Bromo-2-fluoropyridine Asreported | 766-11-0 | 100g | $446 | 2026-06-03 | Buy |
5-Bromo-2-fluoropyridine Chemical Properties,Uses,Production
Description
5-Bromo-2-fluoropyridine is a halogenated pyridine that has been used as a molecular scaffold for many Active Pharmaceutical Ingredients (APIs) such as Neuropeptide Y Receptor Y5 Inhibitors, SARS-CoV-2 Major Protease Inhibitors, and Indoleamine-2,3-Dioxygenase-1 Inhibitors in cancer immunotherapy. 5-Bromo-2-fluoropyridine is also an ideal building block for semiconductors, due to its aromaticity and electron deficiency. A host material of 5-(5-(2,4,6-triiso-propylphenyl)pyridin-2-yl)-5H-benzo[d]benzo-[4,5]imidazo[1,2-a]imidazole is synthesized from 5-bromo-2-fluoropyridine for OLED applications.
Chemical Properties
5-Bromo-2-fluoropyridine is a colourless or yellowish liquid compound with a density of 1.71 g/cm3 at 25° C; boiling point of 162-164° C (lit.) at 750 mmHg; stored at room temperature.
Uses
5-Bromo-2-fluoropyridine is used in the synthesis of heteroaromatic and aniline derivatives of piperidines as potent ligands used for vesicular acetylcholine transport. Also used in the synthesis of benzofurano[3,2-d]pyrimidin-2-one derived inhbitors.
Synthesis
403-45-2
766-11-0
A. Synthesis of 2-fluoro-5-bromopyridine: 2.2 g (15.6 mmol) of 6-fluoronicotinic acid, 5.1 g of red mercuric oxide (HgO) and 1.2 ml of bromine were dissolved in 100 ml of carbon tetrachloride (CCl4) to form a suspension. The reaction was carried out under reflux conditions for 5 hours and subsequently cooled to room temperature. The reaction mixture was filtered through diatomaceous earth and the filtrate was concentrated under vacuum. The residue was dissolved in hexane, filtered again and the filtrate was concentrated under vacuum to give 1.73 g (63% yield) of 2-fluoro-5-bromopyridine, the product being a light yellow oil.
References
[1] Patent: US5618821, 1997, A
5-Bromo-2-fluoropyridine Preparation Products And Raw materials
Raw materials
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Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Beijing Wisdom Chemicals Co., Ltd. | +8613701363759 | market@wisdomchem.com | China | 254 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Wuhan Fortuna Chemical Co., Ltd | +86-27-59207850 | info@fortunachem.com | China | 5983 | 58 |
| Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 973 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20122 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13901 | 58 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| Hi-Tech Chemistry Corp | 0519-86626038 | yuhh@hitechem.com | CHINA | 810 | 58 |
View Lastest Price from 5-Bromo-2-fluoropyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-06-05 | 5-Bromo-2-fluoropyridine
766-11-0
|
1kg | 98% | 1000kg | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-03-20 | 2-Fluoro-5-bromopyridine
766-11-0
|
$10.00 | 1KG | 99% | 5tons | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-12-01 | 5-Bromo-2-fluoropyridine
766-11-0
|
1KG | 99.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd |
-
- 5-Bromo-2-fluoropyridine
766-11-0
- 98%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 2-Fluoro-5-bromopyridine
766-11-0
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 5-Bromo-2-fluoropyridine
766-11-0
- 99.0%
- Shaanxi Dideu New Materials Co. Ltd
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