5-BROMO-2-FLUOROANILINE
- CAS No.
- 2924-09-6
- Chemical Name:
- 5-BROMO-2-FLUOROANILINE
- Synonyms
- 0/6/24;5-Bromo Aniline;5-BROMO-2-FLUOROANIL;5-Bromo-2-fuoroaniline;2-Fluoro-5-Bromoaniline;5-BROMO-2-FLUOROANILINE;2,4-di(propan-2-yl)phenol;5-Bromo-2-fluoroaniline ,98%;Benzenamine, 5-bromo-2-fluoro-;1-Amino-5-bromo-2-fluorobenzene
- CBNumber:
- CB0417457
- Molecular Formula:
- C6H5BrFN
- Molecular Weight:
- 190.01
- MDL Number:
- MFCD03094181
- MOL File:
- 2924-09-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 5-Bromo-2-fluoroaniline >95.0%(GC) | B3043 | 5g | $23 |
| 5-Bromo-2-fluoroaniline >95.0%(GC) | B3043 | 25g | $78 |
| 5-Bromo-2-fluoroaniline Asreported | 263826 | 5g | $305 |
| 5-Bromo-2-fluoroaniline Asreported | 263826 | 10g | $389 |
| 5-Bromo-2-fluoroaniline Asreported | 263826 | 25g | $502 |
| More product size | |||
| Melting point | 27℃ |
|---|---|
| Boiling point | 105 °C / 12mmHg |
| Density | 1.694±0.06 g/cm3(Predicted) |
| refractive index | 1.59 |
| Flash point | 27 °C |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| form | Solid |
| pka | 2.13±0.10(Predicted) |
| color | White or Colorless to Yellow to Orange |
| Water Solubility | Slightly soluble in water. |
| InChI | InChI=1S/C6H5BrFN/c7-4-1-2-5(8)6(9)3-4/h1-3H,9H2 |
| InChIKey | ADWKOCXRCRSMLQ-UHFFFAOYSA-N |
| SMILES | C1(N)=CC(Br)=CC=C1F |
| CAS DataBase Reference | 2924-09-6(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332-H315-H319-H302-H312-H331-H335 | |||||||||
| Precautionary statements | P304+P340-P305+P351+P338-P405-P501a-P261-P264-P270-P271-P280-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P305+P351+P338+P337+P313-P501 | |||||||||
| Hazard Codes | T,Xi,Xn | |||||||||
| Risk Statements | 22-36-52-36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-60-36/37-9 | |||||||||
| RIDADR | 2811 | |||||||||
| Hazard Note | Toxic | |||||||||
| HazardClass | IRRITANT, TOXIC | |||||||||
| HazardClass | 6.1 | |||||||||
| HS Code | 29214990 | |||||||||
| NFPA 704 |
|
5-BROMO-2-FLUOROANILINE price More Price(81)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | B3043 | 5-Bromo-2-fluoroaniline >95.0%(GC) | 2924-09-6 | 5g | $23 | 2026-04-30 | Buy |
| TCI Chemical | B3043 | 5-Bromo-2-fluoroaniline >95.0%(GC) | 2924-09-6 | 25g | $78 | 2026-04-30 | Buy |
| Usbiological | 263826 | 5-Bromo-2-fluoroaniline Asreported | 2924-09-6 | 5g | $305 | 2026-06-03 | Buy |
| Usbiological | 263826 | 5-Bromo-2-fluoroaniline Asreported | 2924-09-6 | 10g | $389 | 2026-06-03 | Buy |
| Usbiological | 263826 | 5-Bromo-2-fluoroaniline Asreported | 2924-09-6 | 25g | $502 | 2026-06-03 | Buy |
5-BROMO-2-FLUOROANILINE Chemical Properties,Uses,Production
Chemical Properties
Light yellow solid
Uses
5-Bromo-2-fluoroaniline is used as pharmaceutical intermediate.
Synthesis
364-73-8
2924-09-6
General procedure for the synthesis of 5-bromo-2-fluoroaniline from 4-bromo-1-fluoro-2-nitrobenzene: 5-bromo-2-fluoro nitrobenzene (698 g) was dissolved in 95% ethanol (0.90 L), which was subsequently added to a mixed system of powdered iron (711 g) and saturated aqueous ammonium chloride (2.0 L). The reaction mixture was stirred continuously at 70°C for 24 hours (the reaction process was monitored by HPLC until complete). Upon completion of the reaction, the mixture was cooled to room temperature, filtered through diatomaceous earth and the filtrate was concentrated under reduced pressure to remove the solvent. The residue was subjected to liquid-liquid extraction with ethyl acetate (2 L) and water (2 L) to separate the organic and aqueous phases. The aqueous phase was further extracted once with ethyl acetate (1L). All organic phases were combined, washed with water (1 L), dried with anhydrous magnesium sulfate, filtered and the organic phase was concentrated under reduced pressure. Finally, 545.76 g of 5-bromo-2-fluoroaniline was obtained in 91% yield by high vacuum treatment for 5 h to completely remove the residual ethyl acetate.
References
[1] Patent: WO2006/48761, 2006, A2. Location in patent: Page/Page column 32
[2] Bioorganic and Medicinal Chemistry Letters, 2015, vol. 25, # 19, p. 4337 - 4341
[3] Patent: WO2005/94822, 2005, A1. Location in patent: Page/Page column 44
[4] Patent: WO2004/52847, 2004, A2. Location in patent: Page 171
[5] Patent: CN104530107, 2016, B. Location in patent: Paragraph 0022
5-BROMO-2-FLUOROANILINE Preparation Products And Raw materials
Raw materials
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Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21587 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Win-Win Chemical CO., Limited | 0086-577-64498589 | sales@win-winchemical.com | CHINA | 998 | 58 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88298848 | info@edengenechem.com | China | 2165 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
View Lastest Price from 5-BROMO-2-FLUOROANILINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-20 | 5-BROMO-2-FLUOROANILINE
2924-09-6
|
1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd | ||
 |
2021-08-12 | 5-BROMO-2-FLUOROANILINE
2924-09-6
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2019-07-06 | 5-BROMO-2-FLUOROANILINE
2924-09-6
|
$1.00 | 1kg | 98% | 100KG | Career Henan Chemical Co |
-
- 5-BROMO-2-FLUOROANILINE
2924-09-6
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 5-BROMO-2-FLUOROANILINE
2924-09-6
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 5-BROMO-2-FLUOROANILINE
2924-09-6
- $1.00
- 98%
- Career Henan Chemical Co
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