3-Chloro-6-methylpyridazine
- CAS No.
- 1121-79-5
- Chemical Name:
- 3-Chloro-6-methylpyridazine
- Synonyms
- NSC 18704;AKOS BBS-00001551;3-Chloro-6-Methyl;Chloro-6-methylpyridazine;3-Chloro-6-Methylpridazine;6-Chloro-3-methylpyridazine;3-CHLORO-6-METHYLPYRIDAZINE;3-Chloro-6-methylpyridazi...;3-Chloro-6-methyl-1,2-diazine;pyridazine, 3-chloro-6-methyl-
- CBNumber:
- CB0420800
- Molecular Formula:
- C5H5ClN2
- Molecular Weight:
- 128.56
- MDL Number:
- MFCD00052905
- MOL File:
- 1121-79-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 3-Chloro-6-methylpyridazine 97% | 637637 | 5g | $57.1 |
| 3-Chloro-6-methylpyridazine 97% | 637637 | 1g | $25 |
| 3-Chloro-6-methylpyridazine >98.0%(GC)(T) | C2274 | 5g | $93 |
| 3-Chloro-6-methylpyridazine >98.0%(GC)(T) | C2274 | 25g | $327 |
| 3-Chloro-6-methylpyridazine | TRC-C365550-5G | 5g | $59 |
| More product size | |||
| Melting point | 58-62 °C |
|---|---|
| Boiling point | 58 °C |
| Density | 1.234±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | DMSO, Methanol (Slightly) |
| form | Solid |
| pka | 1.26±0.10(Predicted) |
| color | Pale Beige |
| BRN | 108655 |
| InChI | InChI=1S/C5H5ClN2/c1-4-2-3-5(6)8-7-4/h2-3H,1H3 |
| InChIKey | PRORLQAJNJMGAR-UHFFFAOYSA-N |
| SMILES | C1(Cl)=NN=C(C)C=C1 |
| CAS DataBase Reference | 1121-79-5(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H315-H317-H318 | |||||||||
| Precautionary statements | P261-P264-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 20/21/22-36/37/38-43-41-38-22 | |||||||||
| Safety Statements | 26-37/39-36/37-37 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Harmful | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29339900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Dam. 1 Skin Irrit. 2 Skin Sens. 1 |
|||||||||
| NFPA 704 |
|
3-Chloro-6-methylpyridazine price More Price(98)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 637637 | 3-Chloro-6-methylpyridazine 97% | 1121-79-5 | 5g | $57.1 | 2026-04-30 | Buy |
| Sigma-Aldrich | 637637 | 3-Chloro-6-methylpyridazine 97% | 1121-79-5 | 1g | $25 | 2023-06-20 | Buy |
| TCI Chemical | C2274 | 3-Chloro-6-methylpyridazine >98.0%(GC)(T) | 1121-79-5 | 5g | $93 | 2026-04-30 | Buy |
| TCI Chemical | C2274 | 3-Chloro-6-methylpyridazine >98.0%(GC)(T) | 1121-79-5 | 25g | $327 | 2026-04-30 | Buy |
| TRC | TRC-C365550-5G | 3-Chloro-6-methylpyridazine | 1121-79-5 | 5g | $59 | 2026-06-03 | Buy |
3-Chloro-6-methylpyridazine Chemical Properties,Uses,Production
Chemical Properties
colorless to yellow liquid
Reactions
3-Chloro-6-methyl pyridazine can undergo nickel catalyzed cross coupling reaction with aromatic and heteroaromatic halides, to give the corresponding substituted aryl- and heteroaryl pyridazines.
Uses
3-Chloro-6-methylpyridazine is used for preparation of heterocyclic compounds as integrase inhibiting antiviral agents.
Definition
ChEBI: 3-Chloro-6-methylpyridazine is a member of pyridazines.
Pharmaceutical Applications
3-Chloro-6-methylpyridazine can be used in the synthesis of a p38MAP kinase inhibitor with therapeutic potential in the treatment of autoimmune and inflammatory diseases.
Synthesis
Add 6-methyl-3(2H)-pyridazinone and chlorinating agent to the reaction vessel; POCl? can act as solvent if used. Heat to 80–120℃, reflux for 2–6 hours to substitute the hydroxyl group of pyridazinone with chlorine. After reaction, slowly pour the solution into ice water to quench excess chlorinating agent, adjust pH to neutral with sodium carbonate or sodium hydroxide. Extract with dichloromethane, ethyl acetate, etc., dry the extract with anhydrous sodium sulfate, remove solvent by reduced pressure distillation to get crude product. Purify via recrystallization (e.g., ethanol-water solvent) or column chromatography to obtain high-purity 3-chloro-6-methylpyridazine.
3-Chloro-6-methylpyridazine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20122 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
| Springchem New Material Technology Co.,Limited | +86-021-62885108 +8613917661608 | info@spring-chem.com | China | 2068 | 57 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13901 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21587 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2994 | 58 |
| Shanghai Arbor Chemical Co., Ltd. | 021-60451682 | act@arborchemical.com | CHINA | 904 | 58 |
View Lastest Price from 3-Chloro-6-methylpyridazine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-11-18 | 3-Chloro-6-methylpyridazine
1121-79-5
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2025-09-25 | 3-Chloro-6-methylpyridazine
1121-79-5
|
$1.00-200.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2022-01-04 | 3-Chloro-6-methylpyridazine
1121-79-5
|
1g | 99%minHPLC | 100kgs/month | Shanghai Rlavie Technology Co ltd |
-
- 3-Chloro-6-methylpyridazine
1121-79-5
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 3-Chloro-6-methylpyridazine
1121-79-5
- $1.00-200.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 3-Chloro-6-methylpyridazine
1121-79-5
- 99%minHPLC
- Shanghai Rlavie Technology Co ltd
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