4-HYDROXY-2-METHYLBENZOIC ACID 98
- CAS No.
- 578-39-2
- Chemical Name:
- 4-HYDROXY-2-METHYLBENZOIC ACID 98
- Synonyms
- 2-Methyl-4-hydroxybenzoic acid;4-HYDROXY-2-METHYLBE;4-hydroxy-o-toluic acid;4-Hydroxy-2-methylbenzoicAcid>Benzoic acid, 4-hydroxy-2-Methyl-;4-HYDROXY-2-METHYLBENZOIC ACID 98;4-Hydroxy-2-Methylbenzoic acid 98%;4-Hydroxy-o-toluic acid, 4-Carboxy-m-cresol;4-Hydroxy-2-Methyl benzoic acid/4-hydroxy-o-toluic acid
- CBNumber:
- CB0498892
- Molecular Formula:
- C8H8O3
- Molecular Weight:
- 152.15
- MDL Number:
- MFCD02182261
- MOL File:
- 578-39-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 4-Hydroxy-2-methylbenzoic acid 98% | 653160 | 10g | $165 |
| 4-Hydroxy-2-methylbenzoic acid 98% | 653160 | 1g | $63 |
| 4-Hydroxy-2-methylbenzoic Acid >98.0%(GC) | H1311 | 5g | $53 |
| 4-Hydroxy-2-methylbenzoic Acid >98.0%(GC) | H1311 | 25g | $166 |
| 4-Hydroxy-2-methylbenzoic acid >98% | OR40557 | 5g | $21 |
| More product size | |||
| Melting point | 177-181 °C |
|---|---|
| Boiling point | 339.1±30.0 °C(Predicted) |
| Density | 1.304±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | soluble in Methanol |
| form | powder to crystal |
| pka | 4.46±0.25(Predicted) |
| color | White to Light yellow to Light orange |
| InChI | InChI=1S/C8H8O3/c1-5-4-6(9)2-3-7(5)8(10)11/h2-4,9H,1H3,(H,10,11) |
| InChIKey | BBMFSGOFUHEVNP-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C1=CC=C(O)C=C1C |
| CAS DataBase Reference | 578-39-2 |
| FDA UNII | U4NMG5AH8R |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H318 | |||||||||
| Precautionary statements | P264-P270-P280-P301+P312-P305+P351+P338-P501 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-41 | |||||||||
| Safety Statements | 26-39 | |||||||||
| WGK Germany | 2 | |||||||||
| HS Code | 29182900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Dam. 1 |
|||||||||
| NFPA 704 |
|
4-HYDROXY-2-METHYLBENZOIC ACID 98 price More Price(60)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 653160 | 4-Hydroxy-2-methylbenzoic acid 98% | 578-39-2 | 10g | $165 | 2026-04-30 | Buy |
| Sigma-Aldrich | 653160 | 4-Hydroxy-2-methylbenzoic acid 98% | 578-39-2 | 1g | $63 | 2023-06-20 | Buy |
| TCI Chemical | H1311 | 4-Hydroxy-2-methylbenzoic Acid >98.0%(GC) | 578-39-2 | 5g | $53 | 2026-04-30 | Buy |
| TCI Chemical | H1311 | 4-Hydroxy-2-methylbenzoic Acid >98.0%(GC) | 578-39-2 | 25g | $166 | 2026-04-30 | Buy |
| Apolloscientific | OR40557 | 4-Hydroxy-2-methylbenzoic acid >98% | 578-39-2 | 5g | $21 | 2026-06-04 | Buy |
4-HYDROXY-2-METHYLBENZOIC ACID 98 Chemical Properties,Uses,Production
Chemical Properties
White or pink crystalline powder
Definition
ChEBI: 4-hydroxy-2-methylbenzoic acid is a hydroxybenzoic acid.
Synthesis
6245-57-4
578-39-2
General procedure for the synthesis of 4-hydroxy-2-methylbenzoic acid from 4-methoxy-2-methylbenzoic acid: boron tribromide (20 mmol, 5 g, 10 eq.) was slowly added to a solution of 4-methoxy-2-methylbenzoic acid (2 mmol, 0.332 g) in dichloromethane (20 mL) under argon protection. The reaction mixture was stirred at room temperature until high performance liquid chromatography (HPLC) analysis showed complete consumption of the feedstock. Subsequently, 0.1 M hydrochloric acid (20 mL) was added to the reaction system to quench the reaction and the insoluble material was removed by filtration. The aqueous phase was concentrated under reduced pressure and the residue was dissolved in methanol and concentrated again under reduced pressure to remove the solvent. This dissolution-concentration process was repeated three times, resulting in purified 4-hydroxy-2-methylbenzoic acid as a yellow solid (0.24 g, 80% yield).
References
[1] European Journal of Organic Chemistry, 2008, # 5, p. 816 - 825
[2] Patent: WO2006/64286, 2006, A1. Location in patent: Page/Page column 93-94
[3] Patent: WO2007/144379, 2007, A1. Location in patent: Page/Page column 39
[4] Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987, vol. 26, p. 679 - 682
[5] Patent: WO2006/79099, 2006, A2. Location in patent: Page/Page column 68; 69
4-HYDROXY-2-METHYLBENZOIC ACID 98 Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou waston chemical technology Co.,Ltd | +86-051985861892 +8618112881323 | info@wastonchem.com | China | 311 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13901 | 58 |
| HaBo Hong Kong Co., Limited. | +86-25-18512596065 | info@habotech.com | CHINA | 933 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 +86-17392581500 | 1015@dideu.com | China | 3991 | 58 |
| Jinan Liheng Biotechnology Co., Ltd. | 15865262812 | info@lihengpharm.com | CHINA | 938 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5742 | 58 |
View Lastest Price from 4-HYDROXY-2-METHYLBENZOIC ACID 98 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-03-30 | 4-HYDROXY-2-METHYLBENZOIC ACID
578-39-2
|
1KG | 98% | 2000 | Shenzhen Nexcon Pharmatechs Ltd. | ||
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2025-12-29 | 4-HYDROXY-2-METHYLBENZOIC ACID 98
578-39-2
|
1kg | 98% | Changzhou waston chemical technology Co.,Ltd | |||
 |
2025-12-01 | 4-HYDROXY-2-METHYLBENZOIC ACID 98
578-39-2
|
1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd |
-
- 4-HYDROXY-2-METHYLBENZOIC ACID
578-39-2
- 98%
- Shenzhen Nexcon Pharmatechs Ltd.
-
- 4-HYDROXY-2-METHYLBENZOIC ACID 98
578-39-2
- $0.00
- 98%
- Changzhou waston chemical technology Co.,Ltd
-
- 4-HYDROXY-2-METHYLBENZOIC ACID 98
578-39-2
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
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