5-FLUOROGRAMINE
- CAS No.
- 343-90-8
- Chemical Name:
- 5-FLUOROGRAMINE
- Synonyms
- 5-FLUOROGRAMINE;5-Fluorogramine 98%;3-(dimethylamino)methyl-5-fluoro-indol;5-FLUORO-3-(DIMETHYLAMINOMETHYL)INDOLE;5-FLUORO-3-DIMETHYLAMINOMETHYL-1H-INDOLE;3-((dimethylamino)methyl)-5-fluoroindole;3-(Dimethylaminomethyl)-5-fluoro-1H-indole;5-fluoro-n,n-dimethyl-1h-indole-3-methanamin;(5-FLUORO-1H-INDOL-3-YLMETHYL)-DIMETHYL-AMINE;5-Fluoro-N,N-dimethyl-1H-indole-3-methanamine
- CBNumber:
- CB0667137
- Molecular Formula:
- C11H13FN2
- Molecular Weight:
- 192.23
- MDL Number:
- MFCD00022731
- MOL File:
- 343-90-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 1-(5-Fluoro-1H-indol-3-yl)-N,N-dimethylmethanamine | FF42157 | 5g | $150 |
| 1-(5-Fluoro-1H-indol-3-yl)-N,N-dimethylmethanamine | FF42157 | 2g | $150 |
| 1-(5-Fluoro-1H-indol-3-yl)-N,N-dimethylmethanamine | FF42157 | 1g | $150 |
| 1-(5-Fluoro-1H-indol-3-yl)-N,N-dimethylmethanamine | FF42157 | 10g | $227.2 |
| 5-Fluorogramine | F-4020 | 1g | $150 |
| More product size | |||
| Melting point | 145-149°C |
|---|---|
| storage temp. | 2-8°C(protect from light) |
| Appearance | White to off-white Solid |
| CAS DataBase Reference | 343-90-8(CAS DataBase Reference) |
| FDA UNII | AM52C35PV7 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P280-P305+P351+P338-P310 |
| Hazard Codes | Xi |
| HS Code | 2933998090 |
5-FLUOROGRAMINE price More Price(55)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FF42157 | 1-(5-Fluoro-1H-indol-3-yl)-N,N-dimethylmethanamine | 343-90-8 | 5g | $150 | 2026-06-04 | Buy |
| Biosynth | FF42157 | 1-(5-Fluoro-1H-indol-3-yl)-N,N-dimethylmethanamine | 343-90-8 | 2g | $150 | 2026-06-04 | Buy |
| Biosynth | FF42157 | 1-(5-Fluoro-1H-indol-3-yl)-N,N-dimethylmethanamine | 343-90-8 | 1g | $150 | 2026-06-04 | Buy |
| Biosynth | FF42157 | 1-(5-Fluoro-1H-indol-3-yl)-N,N-dimethylmethanamine | 343-90-8 | 10g | $227.2 | 2026-06-04 | Buy |
| Biosynth | F-4020 | 5-Fluorogramine | 343-90-8 | 1g | $150 | 2026-06-04 | Buy |
5-FLUOROGRAMINE Chemical Properties,Uses,Production
Synthesis
399-52-0
50-00-0
124-40-3
343-90-8
5-Fluoroindole (1.0 g, 7.40 mmol) was dissolved in 1 mL of acetic acid, and the solution was slowly added dropwise to a mixture of dimethylamine (567 mg, 1.42 mL, 12.58 mmol, 40% aqueous solution) and formaldehyde (333 mg, 0.9 mL, 11.09 mmol, 37% aqueous solution) that had been pre-cooled to 0°C. The reaction was carried out under argon protection . The reaction mixture was stirred without cooling for 3 hours. Upon completion of the reaction, the mixture was poured into 20 mL of ice water and the pH was adjusted with base to 11. Subsequently, the organic products in the aqueous phase were extracted with ether, the organic phases were combined and dried with anhydrous magnesium sulfate. After removal of the solvent by evaporation under reduced pressure, the crude product was purified by silica gel column chromatography with chloroform/methanol/ammonia as eluent (90:10:1 to 40:10:1 gradient elution) to afford the target compound 1-(5-fluoro-1H-indol-3-yl)-N,N-dimethylmethylmethaneamine (1.33 g, 6.92 mmol, 93% yield) as a beige solid. The structure of the product was confirmed by 1H NMR and 13C NMR: 1H NMR (400 MHz, CDCl3) δ 8.47 (s, 1H), 7.36-7.31 (m, 1H), 7.25-7.20 (m, 1H), 7.12 (d, J = 2.6 Hz, 1H), 6.95-6.88 (m, 1H), 3.58 (s, 2H), 2.28 (s, 6H), 3.58 (s, 2H), 3.58 (s, 2H), 3.58 (s, 2H) 2.28 (s, 6H); 13C NMR (100 MHz, CDCl3) δ 157.5 (d, J = 234.4 Hz), 132.4, 128.0 (d, J = 9.9 Hz), 125.1, 113.2 (d, J = 4.9 Hz), 111.3 (d, J = 9.7 Hz), 110.0 (d, J = 26.4 Hz ), 103.87 (d, J = 23.5 Hz), 54.1, 44.9.
References
[1] Journal of Biological Chemistry, 2016, vol. 291, # 38, p. 20068 - 20084
[2] Journal of Organic Chemistry, 2018, vol. 83, # 17, p. 9902 - 9913
[3] Journal of the Chemical Society, 1959, p. 1913
[4] Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1954, vol. 297, p. 229,233
5-FLUOROGRAMINE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8828 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52704 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49962 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 16512 | 58 |
View Lastest Price from 5-FLUOROGRAMINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-08-12 | 5-FLUOROGRAMINE
343-90-8
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
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- 5-FLUOROGRAMINE
343-90-8
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
