1-Methylpyrrolidine
- CAS No.
- 120-94-5
- Chemical Name:
- 1-Methylpyrrolidine
- Synonyms
- N-METHYLPYRROLIDINE;Methylpyrrolidine;1-methyl;Pyrrolidine,1-methyl-;NSC 65579;1-Methylpyrrodine;1-methyl-pyrrolidin;1-METHYLPYRROLIDINE;cefepiMe iMpurity G;Cefepime Impurity 1
- CBNumber:
- CB0672357
- Molecular Formula:
- C5H11N
- Molecular Weight:
- 85.15
- MDL Number:
- MFCD00003173
- MOL File:
- 120-94-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 1-Methylpyrrolidine for synthesis | 8.16146 | 10ml | $47 |
| 1-Methylpyrrolidine for synthesis | 8.16146 | 100mL | $58.6 |
| 1-Methylpyrrolidine ≥98.0% (GC) | 69110 | 100ml | $77.8 |
| 1-Methylpyrrolidine ≥98.0% (GC) | 69110 | 500ml | $164 |
| 1-Methylpyrrolidine >98.0%(GC)(T) | M0415 | 25mL | $26 |
| More product size | |||
| Melting point | -90 °C |
|---|---|
| Boiling point | 76-80 °C (lit.) |
| Density | 0.800 g/mL at 20 °C (lit.) |
| vapor pressure | 100 hPa (20 °C) |
| refractive index |
n |
| FLAVIS Number | 14.137 | 1-Methylpyrrolidine |
| Flash point | −7 °F |
| storage temp. | Store below +30°C. |
| solubility | 213g/l |
| form | Liquid |
| pka | 10.32(at 25℃) |
| color | Clear colorless |
| PH | 11.3 (1g/l, H2O) |
| explosive limit | 1.1-9.1%(V) |
| Water Solubility | fully miscible |
| BRN | 102445 |
| Henry's Law Constant | 3.3×10-1 mol/(m3Pa) at 25℃, Cabani et al. (1971) |
| InChI | 1S/C5H11N/c1-6-4-2-3-5-6/h2-5H2,1H3 |
| InChIKey | AVFZOVWCLRSYKC-UHFFFAOYSA-N |
| SMILES | CN1CCCC1 |
| LogP | 1.1 at 23℃ |
| CAS DataBase Reference | 120-94-5(CAS DataBase Reference) |
| FDA UNII | 06509TZU6C |
| NIST Chemistry Reference | Pyrrolidine, 1-methyl-(120-94-5) |
| EPA Substance Registry System | N-Methylpyrrolidine (120-94-5) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |     GHS02,GHS05,GHS06,GHS09 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H301-H314-H332-H411 | |||||||||
| Precautionary statements | P210-P273-P280-P301+P310+P330-P303+P361+P353-P305+P351+P338 | |||||||||
| PPE | Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | F,C,N | |||||||||
| Risk Statements | 11-22-34-51/53-35-20/22 | |||||||||
| Safety Statements | 16-26-36/37/39-45-61-29 | |||||||||
| RIDADR | UN 2924 3/PG 2 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | UY1420500 | |||||||||
| Autoignition Temperature | 170 °C DIN 51794 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 2933 99 80 | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | II | |||||||||
| Storage Class | 3 - Flammable liquids | |||||||||
| Hazard Classifications | Acute Tox. 3 Oral Acute Tox. 4 Inhalation Aquatic Chronic 2 Flam. Liq. 2 Skin Corr. 1A |
|||||||||
| Toxicity | LD50 orally in Rabbit: 280 mg/kg | |||||||||
| REACH Registrations | Active | |||||||||
| Limited Quantities | 1.0 L (0.3 gallon) (liquid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) | |||||||||
| NFPA 704 |
|
1-Methylpyrrolidine price More Price(44)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.16146 | 1-Methylpyrrolidine for synthesis | 120-94-5 | 10ml | $47 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.16146 | 1-Methylpyrrolidine for synthesis | 120-94-5 | 100mL | $58.6 | 2026-04-30 | Buy |
| Sigma-Aldrich | 69110 | 1-Methylpyrrolidine ≥98.0% (GC) | 120-94-5 | 100ml | $77.8 | 2026-04-30 | Buy |
| Sigma-Aldrich | 69110 | 1-Methylpyrrolidine ≥98.0% (GC) | 120-94-5 | 500ml | $164 | 2026-04-30 | Buy |
| TCI Chemical | M0415 | 1-Methylpyrrolidine >98.0%(GC)(T) | 120-94-5 | 25mL | $26 | 2026-04-30 | Buy |
1-Methylpyrrolidine Chemical Properties,Uses,Production
Chemical Properties
colorless transparent volatile liquid. Freely soluble in water, soluble in alcohol, ether and other organic solvents.
Uses
1-Methylpyrrolidine is a methylated pyrollidine and is involved as an essential part of the structure of cefipime. It is also an active component of cigarette smoke.
Preparation
n-methylpyrrolidine was successfully synthesized in an aqueous medium by using methylamine and 1,4-dibromobutane in the presence of catalyst k2co3 at a moderated temperature. here, n-methylpyrrolidine was firstly synthesized via the green chemistry process, in which both the water solvent and potassium carbonate catalyst were inexpensive and environmentally friendly. also, the reaction temperature was quite moderated at 90°C.
green organic synthesis of n-methylpyrrolidine
Hazard
Flammable, dangerous fire risk. Irritant toskin and eyes.
Flammability and Explosibility
Highly flammable
Safety Profile
Poison by intraperitoneal and intravenous routes. This material is strongly alkaline. Liquid and vapors are corrosive to the skin, eyes, or mucous membranes. A very dangerous fire hazard; keep away from sparks, heat sources, and powerful oxidizers. Keep in closed containers. To fight fire, use alcohol foam. When heated to decomposition it emits highly toxic fumes of NOx.
Synthesis
1-Methylpyrrolidine is prepared by hydrogenation of N-Methylpyrrole over Adams' catalyst.
1-Methylpyrrolidine Preparation Products And Raw materials
Raw materials
Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou Benoy Chemical Co., Ltd | +8617342059697 | sales@benoychem.com | China | 315 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5228 | 58 |
| Henan Aochuang Chemical Co.,Ltd. | +86-0371-63689365 +8618638391208 | sales@aochuangchem.com | China | 9333 | 58 |
| Firsky International Trade (Wuhan) Co., Ltd | +8615387054039 | admin@firsky-cn.com | China | 427 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 16512 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13901 | 58 |
| Dalian Richfortune Chemicals Co., Ltd | +86-86-411-84820922 +86-8613904096939 | sales@richfortunechem.com | China | 305 | 57 |
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- May 26，2025
View Lastest Price from 1-Methylpyrrolidine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-06-08 | 1-Methylpyrrolidine
120-94-5
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
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2026-05-28 | 1-Methylpyrrolidine
120-94-5
|
$2.00-5.00 | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2026-05-21 | 1-Methylpyrrolidine
120-94-5
|
$1.00 | 1KG | 99% | 1000mt/year | Jinan Finer Chemical Co., Ltd |
-
- 1-Methylpyrrolidine
120-94-5
- 0.99
- RongNa Biotechnology Co.,Ltd
-
- 1-Methylpyrrolidine
120-94-5
- $2.00-5.00
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- 1-Methylpyrrolidine
120-94-5
- $1.00
- 99%
- Jinan Finer Chemical Co., Ltd
