ETHYL 2-(BROMOMETHYL)ACRYLATE
- CAS No.
- 17435-72-2
- Chemical Name:
- ETHYL 2-(BROMOMETHYL)ACRYLATE
- Synonyms
- Ethyl Bromomethacrylate;Ethyl 2-(bromomethyl)prop-2-enoate;3-bromo-2-methyl-2-propenoic acid ethyl ester;DK588;NSC 215252;DKFELEX0148;2-Carbethoxyallyl Bromide;Ethyl2-(Bromomethyl)acrvlate;ETHYL 2-(BROMOMETHYL)ACRYLATE;Ethyl 2-(bromomethyl)propenoate
- CBNumber:
- CB0741901
- Molecular Formula:
- C6H9BrO2
- Molecular Weight:
- 193.04
- MDL Number:
- MFCD00031518
- MOL File:
- 17435-72-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Ethyl 2-(bromomethyl)acrylate 98% | 425222 | 1g | $82.3 |
| Ethyl 2-(bromomethyl)acrylate 98% | 425222 | 5g | $262 |
| Ethyl 2-(Bromomethyl)acrylate (stabilized with HQ) >97.0%(GC) | B1820 | 1g | $55 |
| Ethyl 2-(Bromomethyl)acrylate (stabilized with HQ) >97.0%(GC) | B1820 | 5g | $207 |
| Ethyl 2-(bromomethyl)acrylate ≥97%(GC) | 274843 | 1g | $355 |
| More product size | |||
| Melting point | 134-136℃ |
|---|---|
| Boiling point | 38 °C/0.8 mmHg (lit.) |
| Density | 1.398 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | 178 °F |
| storage temp. | -20°C |
| solubility | Chloroform (Sparingly), Ethyl Acetate (Slightly) |
| form | Liquid |
| color | Colorless to pale yellow |
| BRN | 970108 |
| InChI | InChI=1S/C6H9BrO2/c1-3-9-6(8)5(2)4-7/h2-4H2,1H3 |
| InChIKey | MTCMFVTVXAOHNQ-UHFFFAOYSA-N |
| SMILES | C(OCC)(=O)C(CBr)=C |
| CAS DataBase Reference | 17435-72-2(CAS DataBase Reference) |
| UNSPSC Code | 12162002 |
| NACRES | NA.23 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| RIDADR | UN 2810 6.1 / PGII | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10-19-23 | |||||||||
| HazardClass | 6.1 | |||||||||
| HS Code | 29161900 | |||||||||
| Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials |
|||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| Limited Quantities | 100ml (liquid) or 0.5 Kg (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (1g or 1ml) and Max Outer Pack (500g or 500ml) | |||||||||
| NFPA 704 |
|
ETHYL 2-(BROMOMETHYL)ACRYLATE price More Price(59)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 425222 | Ethyl 2-(bromomethyl)acrylate 98% | 17435-72-2 | 1g | $82.3 | 2026-04-30 | Buy |
| Sigma-Aldrich | 425222 | Ethyl 2-(bromomethyl)acrylate 98% | 17435-72-2 | 5g | $262 | 2026-04-30 | Buy |
| TCI Chemical | B1820 | Ethyl 2-(Bromomethyl)acrylate (stabilized with HQ) >97.0%(GC) | 17435-72-2 | 1g | $55 | 2026-04-30 | Buy |
| TCI Chemical | B1820 | Ethyl 2-(Bromomethyl)acrylate (stabilized with HQ) >97.0%(GC) | 17435-72-2 | 5g | $207 | 2026-04-30 | Buy |
| Usbiological | 274843 | Ethyl 2-(bromomethyl)acrylate ≥97%(GC) | 17435-72-2 | 1g | $355 | 2026-06-03 | Buy |
ETHYL 2-(BROMOMETHYL)ACRYLATE Chemical Properties,Uses,Production
Chemical Properties
Colourless Oil
Uses
ETHYL 2-(BROMOMETHYL)ACRYLATE is an intermediate used for the synthesis of aza inhibitors of chorismate mutase.
Uses
It can be employed as an electrophile for various organometallic compounds. The organometallic derivatives of the compound can be used for the synthesis of α-methylene lactones and lactams. It can also be used for the polymerization of functionalized acrylic monomers.
General Description
Ethyl 2-(bromomethyl)acrylate is an allylic alkylating reagent.
Synthesis
10029-04-6
17435-72-2
GENERAL STEPS: Phosphorus tribromide (0.51 mL, 5.4 mmol) was added slowly and dropwise to a stirred solution of ethyl 2-hydroxymethacrylate (2 g, 15.4 mmol) in ether (15 mL) at 0 °C. The reaction mixture was stirred at 0 °C for 3 h and subsequently warmed to room temperature. The reaction was quenched by the addition of water (5 mL) and the product was extracted with hexane (3 x 10 mL). The organic layers were combined, washed with brine (2 × 10 mL), dried over anhydrous MgSO4, filtered and concentrated in vacuum to afford ethyl 2-bromomethacrylate (2.4 g, 12.3 mmol, 82% yield) as a colorless liquid, which could be used in the next reaction without further purification. The product was characterized as follows: colorless oil; 1H NMR (400 MHz, CDCl3) δ 1.30 (t, J = 7.2 Hz, 3H, H6), 4.16 (s, 2H, H4), 4.24 (q, J = 7.0 Hz, 2H, H5), 5.92 (s, 1H, H1'), 6.30 (s, 1H, H1); 13C NMR ( 101 MHz, CDCl3) δ 14.1 (CH3, C6), 29.3 (CH2, C4), 61.2 (CH2, C5), 128.8 (CH2, C1), 137.6 (C, C2), 164.8 (C, C3); IR (νmax, cm-1) 1718 (C=O ester), 1628 (C=C alkene), 1182 (C-O ester), 523 (C-Br); HRMS-EI: m/z [M+H]+ calcd for C6H10BrO2: 192.9864, found: 192.6870.
Purification Methods
If it contains some free acid, add H2O, cool, and neutralise with NaHCO3 until evolution of CO2 ceases. Extract the mixture with Et2O (3x) and dry the combined extracts (Na2SO4, 3hours). Evaporate Et2O and distil the ester collecting fraction b 39-40o/0.9mm and check spectra. [Preparation and NMR: Ramarajan et al. Org Synth Coll Vol VII 211 1990, Beilstein 2 IV 1541.]
References
[1] Journal of Polymer Science, Part A: Polymer Chemistry, 2011, vol. 49, # 6, p. 1513 - 1516
[2] Angewandte Chemie - International Edition, 2016, vol. 55, # 5, p. 1872 - 1875
[3] Angew. Chem., 2016, vol. 128, # 5, p. 1904 - 1907,4
[4] Angewandte Chemie - International Edition, 2017, vol. 56, # 41, p. 12619 - 12623
[5] Angew. Chem., 2017, vol. 129, # 41, p. 12793 - 12797,5
ETHYL 2-(BROMOMETHYL)ACRYLATE Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13901 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10403 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19936 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Richest Group Ltd | 18017061086 | oled@richest-group.com | CHINA | 5600 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| zhangjiagang vinsce bio-pharm. limited. | 86-512-58389969 | sales1@swellxin.com | CHINA | 111 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Alfa Chemistry | info@alfa-chemistry.com | United States | 2344 | 58 |
View Lastest Price from ETHYL 2-(BROMOMETHYL)ACRYLATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-04 | 2-(Bromomethyl)acrylic acid ethyl ester
17435-72-2
|
1kg | 98%+ | 100000kg per Month | Shanghai Qyubiotech Co., Ltd. | ||
 |
2021-08-12 | ETHYL 2-(BROMOMETHYL)ACRYLATE
17435-72-2
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2019-07-06 | ETHYL 2-(BROMOMETHYL)ACRYLATE
17435-72-2
|
$1.00 | 1KG | 98% | 100Kg | Career Henan Chemical Co |
-
- 2-(Bromomethyl)acrylic acid ethyl ester
17435-72-2
- 98%+
- Shanghai Qyubiotech Co., Ltd.
-
- ETHYL 2-(BROMOMETHYL)ACRYLATE
17435-72-2
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- ETHYL 2-(BROMOMETHYL)ACRYLATE
17435-72-2
- $1.00
- 98%
- Career Henan Chemical Co
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