ChemicalBook >> CAS DataBase List >>Tetraisopropyl methylenediphosphonate
Tetraisopropyl methylenediphosphonate
- CAS No.
- 1660-95-3
- Chemical Name:
- Tetraisopropyl methylenediphosphonate
- Synonyms
- Medronic Acid EP Impurity B;Medronic acid impurity B CRS;Tetraisopropyl Methylenediphonate;Bis(diisopropoxyphosphinyl)methane;Tetrakis(1-methylethyl) Methylenedi;tetra-i-Propylmethylenediphosphonate;TETRAISOPROPYL METHYLENEDIPHOSPHONATE;TETRAISOPROPYL(METHYLENE)BISPHOSPHONATE;TetraisopropylMethylenediphosphonate>Tetra-isopropyl methyldiphosphate ester
- CBNumber:
- CB0747453
- Molecular Formula:
- C13H30O6P2
- Molecular Weight:
- 344.32
- MDL Number:
- MFCD00015021
- MOL File:
- 1660-95-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-27 22:54:05
| Product description | Number | Pack Size | Price |
| Medronic acid impurity B European Pharmacopoeia (EP) Reference Standard | Y0001106 | 40 μL | $167 |
| Tetraisopropyl methylenediphosphonate 97% | 426431 | 25ml | $172 |
| Medronic acid impurity B European Pharmacopoeia (EP) Reference Standard | Y0001106 | y0001106 | $91.8 |
| Tetraisopropyl Methylenediphosphonate >97.0%(GC) | M1319 | 25g | $76 |
| Tetraisopropyl Methylenediphosphonate | TRC-T296270-5G | 5g | $91 |
| More product size | |||
| Boiling point | 155 °C/0.5 mmHg (lit.) |
|---|---|
| Density | 1.08 g/mL at 25 °C (lit.) |
| vapor pressure | 0.017Pa at 20℃ |
| refractive index |
n |
| Flash point | 320 °F |
| storage temp. | -20°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | liquid |
| color | Clear Colourless to Yellow |
| Specific Gravity | 1.080 |
| Water Solubility | Insoluble in water. |
| BRN | 1080180 |
| InChI | 1S/C13H30O6P2/c1-10(2)16-20(14,17-11(3)4)9-21(15,18-12(5)6)19-13(7)8/h10-13H,9H2,1-8H3 |
| InChIKey | FKHXXJRKGVDPQP-UHFFFAOYSA-N |
| SMILES | CC(C)OP(=O)(CP(=O)(OC(C)C)OC(C)C)OC(C)C |
| LogP | 1.3 at 20℃ |
| CAS DataBase Reference | 1660-95-3(CAS DataBase Reference) |
| FDA UNII | K46Y5V9U61 |
| NIST Chemistry Reference | Tetraisopropyl methylenediphosphonate(1660-95-3) |
| EPA Substance Registry System | Phosphonic acid, methylenebis-, tetrakis(1-methylethyl) ester (1660-95-3) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H318 | |||||||||
| Precautionary statements | P280-P305+P351+P338+P310 | |||||||||
| PPE | Eyeshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 41 | |||||||||
| Safety Statements | 26-36-39 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29319090 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | Eye Dam. 1 | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
Tetraisopropyl methylenediphosphonate price More Price(56)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0001106 | Medronic acid impurity B European Pharmacopoeia (EP) Reference Standard | 1660-95-3 | 40 μL | $167 | 2026-04-30 | Buy |
| Sigma-Aldrich | 426431 | Tetraisopropyl methylenediphosphonate 97% | 1660-95-3 | 25ml | $172 | 2026-04-30 | Buy |
| Sigma-Aldrich | Y0001106 | Medronic acid impurity B European Pharmacopoeia (EP) Reference Standard | 1660-95-3 | y0001106 | $91.8 | 2024-03-01 | Buy |
| TCI Chemical | M1319 | Tetraisopropyl Methylenediphosphonate >97.0%(GC) | 1660-95-3 | 25g | $76 | 2026-04-30 | Buy |
| TRC | TRC-T296270-5G | Tetraisopropyl Methylenediphosphonate | 1660-95-3 | 5g | $91 | 2026-06-03 | Buy |
Tetraisopropyl methylenediphosphonate Chemical Properties,Uses,Production
Chemical Properties
Clear colorless to slightly yellow liquid
Uses
Tetraisopropyl methylenediphosphonate [T(iPr)MDP] forms a synergistic mixture with hydrogen dicarbollylcobaltate in nitrobenzene which was used in the extraction of europium and americium.
It may be used in the synthesis of the following:
- tetraisopropyl ethenylidenebisphosphonate.
- tetraisopropyl 4-acetylthiobutane-1,1-diphosphonate
- tetraisopropyl 2-(3,5-bis(bromomethyl)phenyl)ethane-1,1-diphosphonate
Uses
Tetraisopropyl Methylenediphosphonate is used in the preparation of E2-bisphosphonate conjugates as potential anti-osteoporosis agents. Also used in the preparation of AZT 5’-Triphosphate compounds which display inhibitory effects on HIV-1 reverse transcrpitase.
General Description
Tetraisopropyl methylenediphosphonate (IPCP) is a tetraisopropyl ester of methylenediphosphonic acid. It is an electroneutral ligand, reported to be synthesized from triisopropyl phosphate. Powder electron paramagnetic resonance (EPR) studies of tris complexes of Cu(II) complexes with IPCP has been analyzed.
Tetraisopropyl methylenediphosphonate Preparation Products And Raw materials
Global( 253)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21587 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Shanghai Yingrui Biopharma Co.,Ltd | 21-33585366 | export01@shyrchem.com | CHINA | 1319 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 9542 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
View Lastest Price from Tetraisopropyl methylenediphosphonate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-20 | Tetraisopropyl methylenediphosphonate
1660-95-3
|
1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd | ||
 |
2025-12-01 | Tetraisopropyl methylenediphosphonate
1660-95-3
|
1kg | 99% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2021-08-12 | Tetraisopropyl methylenediphosphonate
1660-95-3
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- Tetraisopropyl methylenediphosphonate
1660-95-3
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- Tetraisopropyl methylenediphosphonate
1660-95-3
- $0.00
- 99%
- Shaanxi Dideu New Materials Co. Ltd
-
- Tetraisopropyl methylenediphosphonate
1660-95-3
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
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METHYLENEDIPHOSPHONIC ACID TETRAISOPROPYL ESTER
TETRAISOPROPYL(METHYLENE)BISPHOSPHONATE
TETRAISOPROPYL METHYLENEDIPHOSPHONATE
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phosphonicacid,methylenebis-,tetrakis(1-methylethyl)ester
tetra-i-Propylmethylenediphosphonate
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2-[Di(propan-2-yloxy)phosphorylmethyl-propan-2-yloxyphosphoryl]oxypropane
Bis(diisopropoxyphosphinyl)methane
Tetraisopropyl Methylenediphonate
TetraisopropylMethylenediphosphonate>
Medronic acid impurity B CRS
Tetrakis(1-methylethyl) Methylenedi
Phosphonic acid, P,P'-methylenebis-, P,P,P',P'-tetrakis(1-methylethyl) ester
Tetra-isopropyl methyldiphosphate ester
Medronic Acid EP Impurity B
Tetrakis(1-methylethyl) Methylenediphosphonate
1660-95-3
CH2POOCHCH3222
C13H30O6P2
Organic Building Blocks
Phosphonates/Phosphinates
Phosphorus Compounds
Building Blocks
Organic Building Blocks
Phosphonates/Phosphinates
Phosphorus Compounds
