1-Bromo-4-chlorobutane
- CAS No.
- 6940-78-9
- Chemical Name:
- 1-Bromo-4-chlorobutane
- Synonyms
- 4-BROMOBUTYL CHLORIDE;4-CHLOROBUTYL BROMIDE;4-Bromo-1-chlorobutane;NAPRO-008;1-Bromo-4-chL;1-Brom-4-chlorbutan;1-Bromo-4-chloroutane;1-Chloro-4-bromobutane;1-bromo-4-chloro-butan;4-CHLORO-1-BROMOBUTANE
- CBNumber:
- CB0753483
- Molecular Formula:
- C4H8BrCl
- Molecular Weight:
- 171.46
- MDL Number:
- MFCD00001010
- MOL File:
- 6940-78-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 1-Bromo-4-chlorobutane 99% | B60800 | 25g | $49.4 |
| 1-Bromo-4-chlorobutane 99% | B60800 | 100g | $164 |
| 1-Bromo-4-chlorobutane >99.0%(GC) | B1345 | 25g | $36 |
| 1-Bromo-4-chlorobutane >99.0%(GC) | B1345 | 500g | $227 |
| 1-Bromo-4-chlorobutane | TRC-B682650-1G | 1g | $92 |
| More product size | |||
| Melting point | 96-97 °C(Solv: hexane (110-54-3); ethyl acetate (141-78-6)) |
|---|---|
| Boiling point | 80-82 °C/30 mmHg (lit.) |
| Density | 1.488 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | 140 °F |
| storage temp. | Store below +30°C. |
| solubility | soluble in Chloroform |
| form | Liquid |
| color | Clear |
| Water Solubility | SLIGHTLY SOLUBLE |
| BRN | 1098275 |
| InChI | 1S/C4H8BrCl/c5-3-1-2-4-6/h1-4H2 |
| InChIKey | NIDSRGCVYOEDFW-UHFFFAOYSA-N |
| SMILES | ClCCCCBr |
| CAS DataBase Reference | 6940-78-9(CAS DataBase Reference) |
| FDA UNII | 3WY7Z6MQN8 |
| NIST Chemistry Reference | Butane, 1-bromo-4-chloro-(6940-78-9) |
| EPA Substance Registry System | Butane, 1-bromo-4-chloro- (6940-78-9) |
| UNSPSC Code | 12352101 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H226-H302 | |||||||||
| Precautionary statements | P210-P233-P240-P241-P242-P301+P312 | |||||||||
| PPE | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 23-24/25-37/39-26 | |||||||||
| RIDADR | UN 1993 3/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29034980 | |||||||||
| Storage Class | 3 - Flammable liquids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Flam. Liq. 3 |
|||||||||
| REACH Registrations | Active | |||||||||
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
1-Bromo-4-chlorobutane price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | B60800 | 1-Bromo-4-chlorobutane 99% | 6940-78-9 | 25g | $49.4 | 2026-04-30 | Buy |
| Sigma-Aldrich | B60800 | 1-Bromo-4-chlorobutane 99% | 6940-78-9 | 100g | $164 | 2026-04-30 | Buy |
| TCI Chemical | B1345 | 1-Bromo-4-chlorobutane >99.0%(GC) | 6940-78-9 | 25g | $36 | 2026-04-30 | Buy |
| TCI Chemical | B1345 | 1-Bromo-4-chlorobutane >99.0%(GC) | 6940-78-9 | 500g | $227 | 2026-04-30 | Buy |
| TRC | TRC-B682650-1G | 1-Bromo-4-chlorobutane | 6940-78-9 | 1g | $92 | 2026-06-03 | Buy |
1-Bromo-4-chlorobutane Chemical Properties,Uses,Production
Chemical Properties
clear liquid
Uses
1-Bromo-4-chlorobutane is used as a reagent in the synthesis of a novel spirohydantoin derivative as a potent multireceptor-active antipsychotic and antidepressant agent.
Synthesis
30379-55-6
109-70-6
6940-78-9
1. n-Butyllithium (1.6 M hexane solution, 5.0 mL, 8.0 mmol) was added slowly and dropwise to a tetrahydrofuran (THF, 10 mL) solution of diisopropylamine (1.1 mL, 8.0 mmol) at -30 °C and stirred continuously for 30 min at this temperature. 2. the reaction system was cooled down to -70 °C, a solution of (benzyloxy)acetic acid (0.60 g, 3.6 mmol) in THF (5 mL) was added slowly dropwise and stirred for 30 min at the same temperature. 3. Maintaining the -70 °C condition, 1-bromo-3-chloropropane (3.6 mL, 36 mmol) was added to the reaction mixture and stirring was continued for 30 minutes before the reaction system was slowly warmed to room temperature and stirred for 2 hours. 4. The reaction mixture was poured into ice-cold water and washed with ethyl acetate. 5. The pH of the aqueous layer was adjusted to 3-4 with 6 M hydrochloric acid and the mixture was subsequently extracted with ethyl acetate. 6. The organic layers were combined, washed with saturated brine, dried over anhydrous magnesium sulfate and concentrated under reduced pressure to remove the solvent. 7. The crude product was purified by silica gel column chromatography (eluent: hexane/ethyl acetate = 100/0 to 50/50 gradient elution) to afford 1-bromo-4-chlorobutane as a colorless oil (0.28 g, 32% yield). 8. The structure of the product was investigated by 1H NPD analysis. 8. The structure of the product was confirmed by 1H NMR (CDCl3): δ 1.91-2.06 (4H, m), 3.54 (2H, t, J=5.1 Hz), 4.08 (1H, t, J=6.6 Hz), 4.55 and 4.74 (2H, d, J=11.4 Hz), 7.34-7.39 (5H, m).
References
[1] Patent: EP2455380, 2012, A1. Location in patent: Page/Page column 79
1-Bromo-4-chlorobutane Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Yancheng Longshen Chemical Co.,Ltd. | +86-18352073383 +86-18352073383 | sales@longshenchem.com | China | 100 | 55 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 +86-18192627656 | 1059@dideu.com | China | 3587 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5228 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Suzhou Sanyi Polymer Chemical Technology Co., Ltd. | +8615571922873 | 15571922873@163.com | China | 102 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20122 | 58 |
| Shaanxi Franta Biotechnology Co., Ltd | +86-13082019107 | admin@flanderff.com | China | 244 | 58 |
| Hebei Andu Technology Com.,Ltd | +86-86-17798073498 +8617798073498 | aduchemical@163.com | China | 296 | 58 |
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- Feb 5，2026
View Lastest Price from 1-Bromo-4-chlorobutane manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-06-08 | 1-Bromo-4-chlorobutane
6940-78-9
|
1KG | ≥99% | 30 Tons/Month | Yancheng Longshen Chemical Co.,Ltd. | ||
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2026-05-28 | 1-Bromo-4-chlorobutane
6940-78-9
|
$10.00 | 1KG | 99.% | 10 ton | Hebei Chuanghai Biotechnology Co,.LTD | |
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2026-03-20 | 1-Bromo-4-chlorobutane
6940-78-9
|
$10.00 | 1kg | 99% | 100 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- 1-Bromo-4-chlorobutane
6940-78-9
- $0.00
- ≥99%
- Yancheng Longshen Chemical Co.,Ltd.
-
- 1-Bromo-4-chlorobutane
6940-78-9
- $10.00
- 99.%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- 1-Bromo-4-chlorobutane
6940-78-9
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
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