2,2-DIMETHOXYPROPIONIC ACID METHYL ESTER
- CAS No.
- 10076-48-9
- Chemical Name:
- 2,2-DIMETHOXYPROPIONIC ACID METHYL ESTER
- Synonyms
- METHYL PYRUVATE DIMETHYL ACETAL;METHYL 2,2-DIMETHOXYPROPIONATE;METHYL 2,2-DIMETHOXYPROPANOATE;Methyl2,2-Dimethoxypropionate>Dimethoxypropionicacidmethylester;2,2-DIMETHOXYPROPIONIC ACID METHYL ESTER;Propanoic acid, 2,2-dimethoxy-, methyl ester;2,2-DIMETHOXYPROPIONIC ACID METHYL ESTER, 96+%
- CBNumber:
- CB0755447
- Molecular Formula:
- C6H12O4
- Molecular Weight:
- 148.16
- MDL Number:
- MFCD00048066
- MOL File:
- 10076-48-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Methyl 2,2-Dimethoxypropionate >96.0%(GC) | D2382 | 25g | $191 |
| Methyl 2,2-Dimethoxypropionate | KAA07648 | 10g | $251.3 |
| Methyl 2,2-Dimethoxypropionate | KAA07648 | 25g | $392.75 |
| Methyl 2,2-Dimethoxypropionate | KAA07648 | 50g | $707 |
| Methyl 2,2-Dimethoxypropionate | KAA07648 | 100g | $1257 |
| Boiling point | 70 °C / 13mmHg |
|---|---|
| Density | 1.07 |
| refractive index | 1.4100-1.4120 |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | clear liquid |
| color | Colorless to Almost colorless |
| CAS DataBase Reference | 10076-48-9 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H227 |
| Precautionary statements | P210-P280-P370+P378-P403+P235-P501 |
| HS Code | 2918.19.9000 |
2,2-DIMETHOXYPROPIONIC ACID METHYL ESTER price More Price(46)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | D2382 | Methyl 2,2-Dimethoxypropionate >96.0%(GC) | 10076-48-9 | 25g | $191 | 2026-04-30 | Buy |
| Biosynth | KAA07648 | Methyl 2,2-Dimethoxypropionate | 10076-48-9 | 10g | $251.3 | 2026-06-04 | Buy |
| Biosynth | KAA07648 | Methyl 2,2-Dimethoxypropionate | 10076-48-9 | 25g | $392.75 | 2026-06-04 | Buy |
| Biosynth | KAA07648 | Methyl 2,2-Dimethoxypropionate | 10076-48-9 | 50g | $707 | 2026-06-04 | Buy |
| Biosynth | KAA07648 | Methyl 2,2-Dimethoxypropionate | 10076-48-9 | 100g | $1257 | 2026-06-04 | Buy |
2,2-DIMETHOXYPROPIONIC ACID METHYL ESTER Chemical Properties,Uses,Production
Synthesis
600-22-6
149-73-5
10076-48-9
General procedure for the synthesis of methyl 2,2-dimethoxypropionate from methyl pyruvate and trimethyl orthoformate: 100 g (979 mmol) of methyl pyruvate was mixed with 135 g (1273 mmol) of trimethyl orthoformate in 240 ml of methanol. After adding 0.96 g (9.79 mmol) of concentrated sulfuric acid, the mixture was heated to reflux for 4 hours. Subsequently, the solvent was distilled out over 2 h. The crude product was cooled to 10 °C and added to a solution of 2.4 g of potassium hydroxide in 1200 ml of water at 10 °C. After repeated extraction with ether, the organic phases were combined and dried over anhydrous sodium sulfate, filtered and concentrated. The residue was distilled under reduced pressure and the fractions with boiling points of 50-55°C (10 mbar) were collected. Finally 118 g (77% yield) of the target product was obtained.1H NMR (CDCl3) data were as follows: δ = 1.53 (s, 3H, C-CH3), 3.29 (s, 6H, CH3-OCO-CH3), 3.82 (s, 3H, COOCH3).
References
[1] Journal of the American Chemical Society, 1983, vol. 105, # 7, p. 2021 - 2029
[2] Patent: US2015/245616, 2015, A1. Location in patent: Paragraph 0189; 0190
2,2-DIMETHOXYPROPIONIC ACID METHYL ESTER Preparation Products And Raw materials
Raw materials
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Preparation Products
2,2-DIMETHOXYPROPIONIC ACID METHYL ESTER Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88298848 | info@edengenechem.com | China | 2165 | 58 |
| Jinan Liheng Biotechnology Co., Ltd. | 15865262812 | info@lihengpharm.com | CHINA | 938 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
| Alfa Chemistry | +1-5166625404; | Info@alfa-chemistry.com | United States | 20405 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49962 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43333 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Shandong Liteng Biotechnology Co. , Ltd. | +86-18663721413 +86-15552573001 | rosy@litengpharm.com | China | 3280 | 58 |
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