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ChemicalBook >> CAS DataBase List >>2,3-Dihydro-1,4-dioxino[2,3-b]pyridine

2,3-Dihydro-1,4-dioxino[2,3-b]pyridine

CAS No.
129421-32-5
Chemical Name:
2,3-Dihydro-1,4-dioxino[2,3-b]pyridine
Synonyms
2,3-Dihydro-1,4-Dioxino[2,3-b];2H,3H-[1,4]dioxino[2,3-b]pyridine;2,3-Dihydro-1,4-dioxino[2,3-b]pyridine;1,4-Dioxino[2,3-b]pyridine, 2,3-dihydro;Benzoicacid,3-bromo-8-methoxy-,hydrazide;5-Benzofuransulfonylchloride,2,8-dihydro-;2,3-Dihydro-1,4-dioxino[2,3-b]pyridine?New;2,3-dihydro-1,4-dialkanebenzo[2,3-b]pyridine;1,4-Dioxino[2,3-b]pyridine,2,3-dihydro-(9CI);2,3-Dihydro-1,4-dioxino[2,3-b]pyridine ISO 9001：2015 REACH
CBNumber:
CB0854858
Molecular Formula:
C7H7NO2
Molecular Weight:
137.14
MDL Number:
MFCD09743547
MOL File:
129421-32-5.mol
MSDS File:
SDS
Last updated:2026-05-27 22:55:05
Product description Number Pack Size Price
2,3-Dihydro-[1,4]dioxino[2,3-b]pyridine Aldrich ADE000017 1g $870
2,3-Dihydro[1,4]dioxino[2,3-b]pyridine 98% OR53142 500mg $63
2,3-Dihydro[1,4]dioxino[2,3-b]pyridine 98% OR53142 1g $71
2,3-Dihydro-[1,4]dioxino[2,3-b]pyridine 054038 100.00mg $237
2,3-Dihydro-[1,4]dioxino[2,3-b]pyridine 054038 500.00mg $520
More product size

2,3-Dihydro-1,4-dioxino[2,3-b]pyridine Properties

Boiling point 234°C
Density 1.229
Flash point 84°C
storage temp. Sealed in dry,Room Temperature
form solid
pka 4.93±0.20(Predicted)
color Off-white
InChI InChI=1S/C7H7NO2/c1-2-6-7(8-3-1)10-5-4-9-6/h1-3H,4-5H2
InChIKey QWQZJEXJTYAPGE-UHFFFAOYSA-N
SMILES C12OCCOC1=CC=CN=2
UNSPSC Code 12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
WGK Germany  WGK 3
HazardClass  IRRITANT
HS Code  2934999090
Storage Class 11 - Combustible Solids

2,3-Dihydro-1,4-dioxino[2,3-b]pyridine price More Price(57)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich ADE000017 2,3-Dihydro-[1,4]dioxino[2,3-b]pyridine Aldrich 129421-32-5 1g $870 2026-04-30 Buy
Apolloscientific OR53142 2,3-Dihydro[1,4]dioxino[2,3-b]pyridine 98% 129421-32-5 500mg $63 2026-06-04 Buy
Apolloscientific OR53142 2,3-Dihydro[1,4]dioxino[2,3-b]pyridine 98% 129421-32-5 1g $71 2026-06-04 Buy
Matrix Scientific 054038 2,3-Dihydro-[1,4]dioxino[2,3-b]pyridine 129421-32-5 100.00mg $237 2026-05-18 Buy
Matrix Scientific 054038 2,3-Dihydro-[1,4]dioxino[2,3-b]pyridine 129421-32-5 500.00mg $520 2026-05-18 Buy
Product number Packaging Price Buy
ADE000017 1g $870 Buy
OR53142 500mg $63 Buy
OR53142 1g $71 Buy
054038 100.00mg $237 Buy
054038 500.00mg $520 Buy

2,3-Dihydro-1,4-dioxino[2,3-b]pyridine Chemical Properties,Uses,Production

Synthesis

2,3-Dihydroxypyridine

16867-04-2

1,2-Dibromoethane

106-93-4

2,3-Dihydro-1,4-dioxino[2,3-b]pyridine

129421-32-5

a-1) Synthesis of 2,3-dihydro-[1,4]dioxohexa[2,3-b]pyridine 2,3-Dihydroxypyridine (2.22 g, 20.0 mmol) was dissolved in N,N-dimethylformamide (100 mL) and potassium carbonate (5.52 g, 40.0 mmol) was added at room temperature. After stirring for 5 min, 1,2-dibromoethane (2.6 mL, 30.0 mmol) was added slowly and dropwise at the same temperature. The reaction mixture was heated to 90 °C and the reaction was stirred overnight. Upon completion of the reaction, the mixture was cooled to room temperature and filtered to remove the insoluble salt. The filtrate was concentrated under reduced pressure to remove the solvent and the resulting residue was dissolved in ethyl acetate. The suspension was filtered, the filter cake was washed with ethyl acetate, the filtrates were combined and concentrated again under reduced pressure to give 2,3-dihydro-1,4-dioxo[2,3-b]pyridine (157 mg, 5.7% yield) as a colorless oil. 1H-NMR (CDCl3) δ: 4.26-4.28 (2H, m), 4.42-4.44 (2H, m), 6.94 (1H, dd, J = 5.6, 7.6 Hz), 7.28 (1H, dd, J = 1.2, 7.6 Hz), 7.69 (1H, dd, J = 1.2, 5.6 Hz).

References

[1] Patent: US2010/280013, 2010, A1. Location in patent: Page/Page column 49
[2] Patent: WO2015/42397, 2015, A1. Location in patent: Paragraph 000788

2,3-Dihydro-1,4-dioxino[2,3-b]pyridine Preparation Products And Raw materials

Global( 112)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29640 60
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10403 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29792 58
GL Biochem (Shanghai) Ltd. 		+86-021-61263370 +86-18901917034 CHINA 3904 58
ANHUI WITOP BIOTECH CO., LTD 		+8615255079626 eric@witopchemical.com China 23541 58
Shaanxi Dideu Medichem Co. Ltd 		+86-029-89586680 +86-18192503167 1026@dideu.com China 9996 58
Hefei Hirisun Pharmatech Co., Ltd 		+8615056975894 shawn@hirisunpharm.com CHINA 9911 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 +8617705817739 info@dycnchem.com China 52704 58
Nextpeptide Inc 		+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19908 58

View Lastest Price from 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,3-Dihydro-1,4-dioxino[2,3-b]pyridine pictures 2025-06-25 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine
129421-32-5
 $1.10 1g 99.0% min 100 tons min Shaanxi Dideu Medichem Co. Ltd
2,3-Dihydro-1,4-dioxino[2,3-b]pyridine pictures 2019-12-20 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine
129421-32-5
 $1.00 1KG 99% 1000KGS Career Henan Chemical Co

2,3-Dihydro-1,4-dioxino[2,3-b]pyridine Spectrum

1,4-Dioxino[2,3-b]pyridine, 2,3-dihydro 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine 2,3-Dihydro-1,4-Dioxino[2,3-b] 1,4-Dioxino[2,3-b]pyridine,2,3-dihydro-(9CI) 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine ISO 9001：2015 REACH 2H,3H-[1,4]dioxino[2,3-b]pyridine Benzoicacid,3-bromo-8-methoxy-,hydrazide 5-Benzofuransulfonylchloride,2,8-dihydro- 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine?New 2,3-dihydro-1,4-dialkanebenzo[2,3-b]pyridine 129421-32-5 PYRIDINE Heterocycle-Pyridine series
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