sulfaguanole
- CAS No.
- 27031-08-9
- Chemical Name:
- sulfaguanole
- Synonyms
- Sulfaguanol;sulfaguanole;4-Amino-N-[[(4,5-dimethyl-2-oxazolyl)amino](imino)methyl]benzenesulfonamide;Benzenesulfonamide, 4-amino-N-[[(4,5-dimethyl-2-oxazolyl)amino]iminomethyl]-
- CBNumber:
- CB0923240
- Molecular Formula:
- C12H15N5O3S
- Molecular Weight:
- 309.34
- MDL Number:
- MOL File:
- 27031-08-9.mol
| Product description | Number | Pack Size | Price |
| SULFAGUANOL 95.00% | API0025358 | 5MG | $503.98 |
| Melting point | 233-236°; mp 228-230° |
|---|---|
| Boiling point | 510.0±52.0 °C(Predicted) |
| Density | 1.53±0.1 g/cm3(Predicted) |
| pka | 7.76(at 25℃) |
| FDA UNII | 0X9P7B60UD |
sulfaguanole Chemical Properties,Uses,Production
Originator
Enterocura,Nordmark,W. Germany,1973
Definition
ChEBI: Sulfaguanole is a sulfonamide.
Manufacturing Process
23.9 grams (0.1 mol) of N1-[p-amino benzene sulfonyl]-N3-cyanoguanidine
and 13.2 grams (0.15 mol) of acetoin are thoroughly stirred in a mixture of
120 cc of water and 120 cc of methanol. 25 cc of concentrated hydrochloric
acid are added dropwise with stirring to this suspension at 40°C. A clear
solution is obtained after 30 minutes which solution is kept at 40°C for
another hour. Thereafter, the methanol is distilled off in a vacuum, the
remaining solution is treated with charcoal and the pH of the filtered solution
is quickly brought to 11 by addition of 10% soda lye with quick stirring.
The compound at first precipitated is redissolved at a pH of 11. The solution is
treated another time with charcoal and is filtered. Thereafter, a mixture of
anhydrous acetic acid and water in a proportion of 1:1 is added with stirring
and cooling until a pH of 7 is reached. Thus, the reaction product separates
with crystallization.
For purification, the product is recrystallized from 15 times the amount of a
9:1 mixture of acetone and water. The resulting N1-[p-amino benzene
sulfonyl] -N3-(4,5-dimethyl-oxazolyl-(2)]-guanidine is obtained as colorless
crystals having a MP of 233° to 236°C.
Therapeutic Function
Antibacterial
sulfaguanole Preparation Products And Raw materials
Raw materials
Preparation Products
sulfaguanole Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53803 | 58 |
| Supplier | Advantage |
|---|---|
| DAYANG CHEM (HANGZHOU) CO.,LTD | 58 |
