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ChemicalBook >> CAS DataBase List >>3'-Amino-4'-methoxyacetanilide

3'-Amino-4'-methoxyacetanilide

CAS No.
6375-47-9
Chemical Name:
3'-Amino-4'-methoxyacetanilide
Synonyms
3-AMINO-4-METHOXY ACETANILIDE;2-Methoxy-5-(acetylamino)aniline;N-(3-AMINO-4-METHOXYPHENYL)ACETAMIDE;TIMTEC-BB SBB000217;5-ACETAMIDO-O-ANISIDINE;o-Amino-p-acetanisidine;3-Amino-p-acetanisidide;4-ACETAMIDO-2-AMINOANISOLE;4-ACETAMINO-2-AMINOANISOLE;2-AMINO-4-ACETAMIDOANISOLE
CBNumber:
CB1104453
Molecular Formula:
C9H12N2O2
Molecular Weight:
180.2
MDL Number:
MFCD00008676
MOL File:
6375-47-9.mol
Last updated:2026-05-27 23:00:59
Product description Number Pack Size Price
3'-Amino-4'-methoxyacetanilide >98.0%(HPLC)(T) A1064 25g $33
3'-Amino-4'-methoxyacetanilide >98% OR322001 100g $21
3'-Amino-4'-methoxyacetanilide >98% OR322001 500g $49
3'-Amino-4'-methoxyacetanilide >98% OR322001 2.5kg $240
3'-Amino-4'-methoxyacetanilide >98% OR322001 10kg $952
More product size

3'-Amino-4'-methoxyacetanilide Properties

Melting point 109°C
Boiling point 313.03°C (rough estimate)
Density 1.1819 (rough estimate)
refractive index 1.5373 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility soluble in Methanol
form powder to crystal
pka 14.23±0.70(Predicted)
color White to Gray to Brown
Stability Hygroscopic
InChI InChI=1S/C9H12N2O2/c1-6(12)11-7-3-4-9(13-2)8(10)5-7/h3-5H,10H2,1-2H3,(H,11,12)
InChIKey SJWQCBCAGCEWCV-UHFFFAOYSA-N
SMILES C(NC1=CC=C(OC)C(N)=C1)(=O)C
CAS DataBase Reference 6375-47-9(CAS DataBase Reference)
NIST Chemistry Reference 2-Amino-4-acetamino anisole(6375-47-9)
EPA Substance Registry System Acetamide, N-(3-amino-4-methoxyphenyl)- (6375-47-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H302-H319
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39
WGK Germany  1
TSCA  TSCA listed
HazardClass  IRRITANT
HS Code  2924297099
NFPA 704
0
1 0

3'-Amino-4'-methoxyacetanilide price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical A1064 3'-Amino-4'-methoxyacetanilide >98.0%(HPLC)(T) 6375-47-9 25g $33 2024-03-01 Buy
Apolloscientific OR322001 3'-Amino-4'-methoxyacetanilide >98% 6375-47-9 100g $21 2026-06-04 Buy
Apolloscientific OR322001 3'-Amino-4'-methoxyacetanilide >98% 6375-47-9 500g $49 2026-06-04 Buy
Apolloscientific OR322001 3'-Amino-4'-methoxyacetanilide >98% 6375-47-9 2.5kg $240 2026-06-04 Buy
Apolloscientific OR322001 3'-Amino-4'-methoxyacetanilide >98% 6375-47-9 10kg $952 2026-06-04 Buy
Product number Packaging Price Buy
A1064 25g $33 Buy
OR322001 100g $21 Buy
OR322001 500g $49 Buy
OR322001 2.5kg $240 Buy
OR322001 10kg $952 Buy

3'-Amino-4'-methoxyacetanilide Chemical Properties,Uses,Production

Chemical Properties

White crystals. Melting point 116-118 ℃.

Uses

3'-Amino-4'-methoxyacetanilide mainly used as a disperse dye intermediate

Synthesis

2,4-DIAMINOANISOLE

615-05-4

Acetic anhydride

108-24-7

3'-Amino-4'-methoxyacetanilide

6375-47-9

In conjunction with the accompanying drawings, a continuous flow reactor equipped with a solid-liquid separator was connected to a constant-flow pressure pump and a nitrogen cylinder, respectively. First, nitrogen was introduced to displace the air in the reaction system, followed by heating the first part of the reactor to the set temperature using an oil bath and adjusting the pressure of the first reactor to the desired value by means of a back pressure valve. A methanol solution of 2,4-dinitroanisole with catalyst (1% Pd/C, particle size <100 μm) was introduced from inlet 1 via a metering pump, preheated and fed into the tubular continuous flow reactor. At the same time, hydrogen was introduced from inlet 2 via a gas flow meter into the same reactor. After reacting at a specific temperature and pressure for a certain period of time, the mixture enters a gas-liquid-solid separator, where the catalyst is separated and recycled, while the liquid phase is introduced directly into the second reactor through inlet 3. In the second reactor, acid and acetic anhydride are added from feed ports 4 and 5, respectively, via a metering pump, and mixed with hydrogen and reacted at a set temperature. Upon completion of the reaction, the mixture entered the post-treatment tank, and was subjected to filtration, distillation to recover methanol, washing and recrystallization steps to finally obtain 3-amino-4-methoxyacetanilide. The process has a maximum yield of 99% and a product purity of 99.9% (see Example 11).

References

[1] Patent: CN106966915, 2017, A. Location in patent: Paragraph 0031; 0032; 0033; 0034; 0035; 0036-0042
[2] Patent: CN105348132, 2016, A. Location in patent: Paragraph 0066; 0067
[3] Patent: CN104926679, 2016, B. Location in patent: Paragraph 0016; 0017; 0019; 0021
[4] Patent: CN108409593, 2018, A. Location in patent: Paragraph 0037; 0047-0049
[5] Patent: CN108440333, 2018, A. Location in patent: Paragraph 0037; 0056-0064

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View Lastest Price from 3'-Amino-4'-methoxyacetanilide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3'-Amino-4'-methoxyacetanilide pictures 2026-05-28 3'-Amino-4'-methoxyacetanilide
6375-47-9
 $60.00 1KG 99.9% 100000kg Hebei Chuanghai Biotechnology Co,.LTD
3′-Amino-4′-methoxyacetanilide pictures 2025-04-15 3′-Amino-4′-methoxyacetanilide
6375-47-9
 $45.00 1kg 99% 5000kg/week Hebei Zhuanglai Chemical Trading Co.,Ltd
3 2021-08-12 3"-Amino-4"-methoxyacetanilide
6375-47-9
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
3-AMINO-4-METHOXYACETANILINE 3'-AMINO-4'-METHOXYACETOANILIDE 4-ACETOAMINO-2-AMINO METHOXYBENZENE 4-ACETAMINO-2-AMINOANISOLE 5-ACETAMIDO-O-ANISIDINE n-(3-amino-4-methoxyphenyl)-acetamid 3'-AMINO-4'-METHOXYACETANILIDE TECH. & o-Amino-p-acetanisidine 3-AMINO-4-METHOXY ACETANILIDE PHOSPHATE 4-ACETAMIDO-2-AMINOANISOLE 3''-AMINO-4''-METHOXYACETOANILIDE 95+% 3-AMINO-4-METHOXYACERANILIDE 3-Amino-4-methoxyacetylaniline 2-AMINO-4-ACETAMIDOANISOLE 2-AMINO-4-ACETYLAMINOANISOLE Acetamide, N-(3-amino-4-methoxyphenyl)- Acetamide,N-(3-amino-4-methoxyphenyl)- N-(3-amino-4-methoxyphenyl)acetamide(SALTDATA: FREE) 5-Acetamido-o-anisidine N1-Acetyl-4-methoxy-1,3-phenylenediamine 2-Methoxy-5-acetaminoaniline 5-Acetylamino-2-methoxyaniline 3-Amino-4-Methoxy Acetaniline(AMA) 3-Amino-p-acetanisidide p-Acetanisidide, 3'-amino- TIMTEC-BB SBB000217 N1-ACETYL-4-METHOXY-1,3-PHENYLENEDIAMINE 2-Amino-4-acetaminoanisole N-(3-amino-4-methoxy-phenyl)ethanamide 3'-Amino-4'-methoxyacetanilide ISO 9001：2015 REACH 3'-Amino-4'-methoxyacetanilide > 3,3-bis(4-hydroxy-3-methoxyphenyl)-1H-indol-2-one -Methylpiperazine-1-carbonyl)phenyl]boronic acid pinacol ester 3'-Amino-4'-methoxyacetanilide 6375-47-9 N-(3-amino-4-methoxyphenyl)acetamide 2-Amino-4-acetamino anisole 3-Amino-4-Methoxy Acetanilide 6375-47-9 Manufacturer High quality Best price In stock factory N-(3-amino-4-methoxyphenyl)acetamide 2-Amino-4-acetamino anisole 6375-47-9 3-Amino-4-Methoxy Acetanilide 6375-47-9 In stock N-(3-amino-4-methoxyphenyl)acetamide 2-Amino-4-acetamino anisole 6375-47-9 3'-Amino-4'-methoxyacetanilide 2-Amino-4-acetamidomethoxybenzene 2-Methoxy-5-(acetylamino)aniline 3-AMINO-4-METHOXY ACETANILIDE N-(3-AMINO-4-METHOXYPHENYL)ACETAMIDE 6375-47-9 6376-47-9 5431-89-4 CH3CONHC6H3NH2OCH3 CH3OC6H3NH2NHCOCH3 Protected Amines Organic Building Blocks Nitrogen Compounds Building Blocks Intermediates of Dyes and Pigments
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