2-AMINOQUINOXALINE
- CAS No.
- 5424-05-5
- Chemical Name:
- 2-AMINOQUINOXALINE
- Synonyms
- quinoxalin-2-amine;NSC 44679;NSC 13155;2-Quinoxalinamine;2-Aminequinoxalin;2-AMINOQUINOXALINE;quinoxalin-2-ylamine;2-Aminoquinoxaline ,97%;quinoxalin-2-amine - [Q86934]
- CBNumber:
- CB1105788
- Molecular Formula:
- C8H7N3
- Molecular Weight:
- 145.16
- MDL Number:
- MFCD00094018
- MOL File:
- 5424-05-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Quinoxalin-2-amine 97% | OR938970 | 250mg | $32 |
| Quinoxalin-2-amine 97% | OR938970 | 1g | $94 |
| Quinoxalin-2-amine 97% | OR938970 | 5g | $324 |
| Quinoxalin-2-amine 97% | OR938970 | 250mg | $32 |
| Quinoxalin-2-amine 97% | OR938970 | 1g | $94 |
| More product size | |||
| Melting point | 155-157℃ |
|---|---|
| Boiling point | 297.6±20.0 °C(Predicted) |
| Density | 1.292 |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 3.70±0.28(Predicted) |
| form | Solid |
| color | Light Yellow |
| InChI | InChI=1S/C8H7N3/c9-8-5-10-6-3-1-2-4-7(6)11-8/h1-5H,(H2,9,11) |
| InChIKey | YOWAEZWWQFSEJD-UHFFFAOYSA-N |
| SMILES | N1C2C(=CC=CC=2)N=CC=1N |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501 |
| Hazard Codes | Xn |
| Risk Statements | 22-36/38-20/21/22 |
| Safety Statements | 26-36/37-15 |
| HS Code | 29339900 |
2-AMINOQUINOXALINE price More Price(63)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR938970 | Quinoxalin-2-amine 97% | 5424-05-5 | 250mg | $32 | 2026-06-04 | Buy |
| Apolloscientific | OR938970 | Quinoxalin-2-amine 97% | 5424-05-5 | 1g | $94 | 2026-06-04 | Buy |
| Apolloscientific | OR938970 | Quinoxalin-2-amine 97% | 5424-05-5 | 5g | $324 | 2026-06-04 | Buy |
| Apolloscientific | OR938970 | Quinoxalin-2-amine 97% | 5424-05-5 | 250mg | $32 | 2026-06-04 | Buy |
| Apolloscientific | OR938970 | Quinoxalin-2-amine 97% | 5424-05-5 | 1g | $94 | 2026-06-04 | Buy |
2-AMINOQUINOXALINE Chemical Properties,Uses,Production
Chemical Properties
Yellow solid
Uses
2-Aminoquinoxaline is an aminopyrazine analog with potential use as chemiluminescence derivatization reagents for pyruvic acid.
Synthesis Reference(s)
Journal of the American Chemical Society, 73, p. 4955, 1951 DOI: 10.1021/ja01154a143
Synthesis
34117-90-3
829-85-6
5424-05-5
1422239-76-6
4559-70-0
1101-41-3
A mixture of 2-amino-3-chloroquinoxaline (495 mg, 2.75 mmol) and diphenylphosphine (0.48 mL, 2.76 mmol) was heated and reacted at 130 °C for 2 h under the catalytic influence of Pd(OAc)2 (0.8 mg, 0.13 mmol) to give a viscous blue-green product. The reaction mixture was extracted with diethyl ether and the soluble fraction was monitored by NMR in C6D6 to identify tetraphenyl diphenylphosphine (Ph2P-PPh2), diphenylchlorophosphine (Ph2PCl), 2-aminoquinoxaline (3a), and an unknown phosphorus compound (31P NMR signals: δ 14.9, 82.2, 12.8, 5.4 ppm, intensity ratio 84:12:2:2). The ether-insoluble hydrochloride fraction was treated with aqueous NaOH/Et2O to give 615 mg of blue-green powder. The ether phase was dried over Na2SO4 and the ether was removed under reduced pressure to give 220 mg of a brownish-yellow viscous substance with a low content of 2-aminoquinoxaline (about 20% relative intensity of 31P in addition to signals from tetraphenyldiphosphine, diphenyloxyphosphine and other phosphorus compounds). The mixture was purified by silica gel column chromatography (ethyl acetate/hexane, 95/5%) under aerobic conditions, and removal of the solvent afforded 180 mg (45% yield) of 2-aminoquinoxaline as a light yellow solid, with a melting point of 156 °C.1H NMR (CDCl3) δ: 5.03 (vbr, 2H, NH2), 7.45 (td, 3J = 8.4, 7, 4J = 1.2 Hz, 1H, H-6), 7.61 (td, 3J = 8.4, 7, 4J = 1.2 Hz, 1H, H-7), 7.67 (dd, 3J = 8.4, 4J = 1.2 Hz, 1H, H-8), 7.92 (dd, 3J = 8.4, 4J = 1.2 Hz, 1H, H-5), 8.35 (s, 1H, H-3); these data are in agreement with the literature [17]. literature [17].13C NMR (CDCl3) δ: 125.05 (CH-6), 125.88 (CH-8), 128.83 (CH-5), 137.43 (Cq-4a), 137.78 (CH-3), 130.29 (CH-7), 140.89 (Cq-8a), 151.97 (Cq-2). HRMS (ESI in MeOH): calculated value C8H7N3 [M+H]+ 146.0713; measured value: 146.0713.
References
[1] Polyhedron, 2013, vol. 50, # 1, p. 101 - 111
2-AMINOQUINOXALINE Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 +86-17392581500 | 1015@dideu.com | China | 3991 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8615965530500 | nickzhang@hangyubiotech.com | China | 9948 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Suzhou ARTK Medchem Co., Ltd. | +8618118463618 | sales1@artkmedchem.com | China | 39021 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53803 | 58 |
View Lastest Price from 2-AMINOQUINOXALINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | 2-AMINOQUINOXALINE
5424-05-5
|
$8.00 | 1kg | 99% | 10tons | Career Henan Chemical Co |
-
- 2-AMINOQUINOXALINE
5424-05-5
- $8.00
- 99%
- Career Henan Chemical Co
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