6-chloro-2-methyl-4(1H)-quinazolinone
- CAS No.
- 7142-09-8
- Chemical Name:
- 6-chloro-2-methyl-4(1H)-quinazolinone
- Synonyms
- 6-chlro-2-Methylquinazolin-4-ol;6-CHLORO-2-METHYLQUINAZOLIN-4(3H)-ONE;NSC 45786;6-chloro-2-methylquinazolin-4-ol;6-Chloro-2-methylquinazolin-4(3H);6-chloro-2-methylquinazolin-4(1H)-one;6-Chloro-2-Methyl-3H-quinazolin-4-one;6-chloro-2-methyl-4(1H)-quinazolinone;6-Chloro-4-hydroxy-2-methylquinazoline;4(3H)-Quinazolinone, 6-chloro-2-methyl-
- CBNumber:
- CB11373470
- Molecular Formula:
- C9H7ClN2O
- Molecular Weight:
- 194.62
- MDL Number:
- MFCD00195330
- MOL File:
- 7142-09-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 6-CHLORO-2-METHYL-3H-QUINAZOLIN-4-ONE AldrichCPR | S188131 | 1 unit | $152 |
| 6-CHLORO-2-METHYL-3H-QUINAZOLIN-4-ONE AldrichCPR | S188131 | 5MG | $139 |
| 6-Chloro-2-methylquinazolin-4(3H)-one 97% | OR906046 | 250mg | $25 |
| 6-Chloro-2-methylquinazolin-4(3H)-one 97% | OR906046 | 1g | $30 |
| 6-Chloro-2-methylquinazolin-4(3H)-one 97% | OR906046 | 5g | $62 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H319 |
| Precautionary statements | P305+P351+P338 |
| HS Code | 2933998090 |
6-chloro-2-methyl-4(1H)-quinazolinone price More Price(45)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S188131 | 6-CHLORO-2-METHYL-3H-QUINAZOLIN-4-ONE AldrichCPR | 7142-09-8 | 1 unit | $152 | 2026-04-30 | Buy |
| Sigma-Aldrich | S188131 | 6-CHLORO-2-METHYL-3H-QUINAZOLIN-4-ONE AldrichCPR | 7142-09-8 | 5MG | $139 | 2024-03-01 | Buy |
| Apolloscientific | OR906046 | 6-Chloro-2-methylquinazolin-4(3H)-one 97% | 7142-09-8 | 250mg | $25 | 2026-06-04 | Buy |
| Apolloscientific | OR906046 | 6-Chloro-2-methylquinazolin-4(3H)-one 97% | 7142-09-8 | 1g | $30 | 2026-06-04 | Buy |
| Apolloscientific | OR906046 | 6-Chloro-2-methylquinazolin-4(3H)-one 97% | 7142-09-8 | 5g | $62 | 2026-06-04 | Buy |
6-chloro-2-methyl-4(1H)-quinazolinone Chemical Properties,Uses,Production
Uses
6-Chloro-4-hydroxy-2-methylquinazoline is a quinazolinone/quinazoline derivative.
Synthesis
21739-93-5
124-42-5
7142-09-8
A magnetic stirrer was charged into a two-necked round-bottomed flask, evacuated and displaced three times with nitrogen. An aqueous solution (3 mL) of 2 wt% TPGS-750-M in 2-bromo-5-chlorobenzoic acid (1, 0.5 mmol) and acetamidine hydrochloride (2, 0.75 mmol) was added under nitrogen protection. After stirring for 10 min, Cs2CO3 (1 mmol, 326 mg) was added to the flask. 15 min later, CuI (0.1 mmol, 19 mg) was added. The reaction mixture was stirred at the indicated temperature (see Table 3 in the text) for 12 h under nitrogen atmosphere. Upon completion of the reaction, the mixture was extracted with ethyl acetate (1 mL) and concentrated under reduced pressure. The residue was purified by silica gel column chromatography using petroleum ether/ethyl acetate (3:1 to 1:1) as eluent to afford 6-chloro-2-methylquinazolin-4-one.
References
[1] RSC Advances, 2014, vol. 4, # 91, p. 50285 - 50294
[2] Angewandte Chemie - International Edition, 2009, vol. 48, # 2, p. 348 - 351
[3] Tetrahedron, 2015, vol. 71, # 29, p. 4853 - 4858
[4] Applied Organometallic Chemistry, 2014, vol. 28, # 9, p. 661 - 665
6-chloro-2-methyl-4(1H)-quinazolinone Preparation Products And Raw materials
6-chloro-2-methyl-4(1H)-quinazolinone Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43333 | 58 |
| Nanjing Bicbiotechnology Co., Ltd | +86-2552131256 +86-18251840740 | sales@bicbiotech.com | China | 5994 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd. | 21-57721279 18121011378 | sales@shydchem.com.cn | China | 998 | 56 |
| China Langchem Inc. | 0086-21-58956006 | China | 7811 | 57 | |
| NovoChemy Ltd. | -- | sales@novochemy.com | Germany | 6328 | 58 |
| Shanghai T&W Pharmaceutical Co., Ltd. | +86 21 61551611 | China | 9891 | 58 | |
| SynAsst Chemical. | 021-60343070 | China | 12740 | 55 |
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