3-isoquinolinecarboxaldehyde
- CAS No.
- 5470-80-4
- Chemical Name:
- 3-isoquinolinecarboxaldehyde
- Synonyms
- Isoquinoline-3-carbaldehyde;3-Formylisoquinoline;3-isoquinolinecarboxaldehyde;isoquinoline-3-methylaldehyde;Isoquinoline-3-carboxaldehyde;Isoquinoline-3-carboxaldehyde 95%;3-Formylisoquinoline, 3-Formyl-2-azanaphthalene;3-isoquinolinecarboxaldehyde ISO 9001：2015 REACH;3-Isoquinolinecarboxaldehyde (6CI, 7CI, 8CI, 9CI, ACI)
- CBNumber:
- CB11458256
- Molecular Formula:
- C10H7NO
- Molecular Weight:
- 157.17
- MDL Number:
- MFCD06227437
- MOL File:
- 5470-80-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Isoquinoline-3-carboxaldehyde 95% | OR40275 | 250mg | $30 |
| Isoquinoline-3-carbaldehyde 97% | AS1304 | 1g | $114 |
| Isoquinoline-3-carbaldehyde 97% | AS1304 | 5g | $476 |
| Isoquinoline-3-carbaldehyde 97% | AS1304 | 25g | $1588 |
| Isoquinoline-3-carbaldehyde | 298599 | 1.00g | $71 |
| Melting point | 47 °C |
|---|---|
| Boiling point | 151 °C(Press: 10 Torr) |
| Density | 1.223±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | solid |
| pka | 2.94±0.30(Predicted) |
| color | White |
| InChI | InChI=1S/C10H7NO/c12-7-10-5-8-3-1-2-4-9(8)6-11-10/h1-7H |
| InChIKey | XOYMAJLARWXZBA-UHFFFAOYSA-N |
| SMILES | C1C2=C(C=CC=C2)C=C(C=O)N=1 |
| FDA UNII | AG4ERY67PZ |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312+H332-H315-H319-H335 |
| Precautionary statements | P271-P280 |
| HS Code | 2933499090 |
3-isoquinolinecarboxaldehyde price More Price(49)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR40275 | Isoquinoline-3-carboxaldehyde 95% | 5470-80-4 | 250mg | $30 | 2026-06-04 | Buy |
| Activate Scientific | AS1304 | Isoquinoline-3-carbaldehyde 97% | 5470-80-4 | 1g | $114 | 2026-06-04 | Buy |
| Activate Scientific | AS1304 | Isoquinoline-3-carbaldehyde 97% | 5470-80-4 | 5g | $476 | 2026-06-04 | Buy |
| Activate Scientific | AS1304 | Isoquinoline-3-carbaldehyde 97% | 5470-80-4 | 25g | $1588 | 2026-06-04 | Buy |
| Matrix Scientific | 298599 | Isoquinoline-3-carbaldehyde | 5470-80-4 | 1.00g | $71 | 2026-05-19 | Buy |
3-isoquinolinecarboxaldehyde Chemical Properties,Uses,Production
Synthesis Reference(s)
Journal of the American Chemical Society, 73, p. 688, 1951 DOI: 10.1021/ja01146a055
Synthesis
27104-73-0
5470-80-4
General procedure for the synthesis of isoquinoline-3-carbaldehyde from methyl isoquinoline-3-carboxylate: methyl isoquinoline-3-carboxylate (2.0 g, 10.7 mmol) was dissolved in toluene and the solution was cooled to -78 °C. Diisobutylaluminum hydride (1 M solution in toluene, 21.4 mL, 21.4 mmol) was slowly added to this solution using a syringe over a period of 15 minutes. Keeping the reaction mixture at -78 °C, the reaction was quenched with a mixture of ether (80 mL), acetic acid (20 mL) and water (8 mL). The mixture was then slowly warmed to room temperature and stirred overnight. The organic layer was separated and the solvent was evaporated. Purification by fast column chromatography (eluent gradient: 1:4 ethyl acetate/hexane to 1:3 ethyl acetate/hexane) afforded 1.1 g of the title compound isoquinoline-3-carbaldehyde in 65% yield.1H-NMR (CDCl3, 300 MHz) δ 10.24 (s, 1H), 9.35 (s, 1H), 8.36 (s, 1H), 8.07- 7.98 (m, 2H), 7.82-7.32 (m, 2H). MS: m/z 158 ([MH]+).
References
[1] Patent: WO2005/56550, 2005, A2. Location in patent: Page/Page column 75-76
[2] Patent: WO2005/92885, 2005, A1. Location in patent: Page/Page column 73
[3] Patent: WO2005/56562, 2005, A1. Location in patent: Page/Page column 71-72
[4] Tetrahedron Letters, 1999, vol. 40, # 6, p. 1211 - 1214
[5] Patent: US5554620, 1996, A
3-isoquinolinecarboxaldehyde Preparation Products And Raw materials
Raw materials
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Preparation Products
3-isoquinolinecarboxaldehyde Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 20582 | 58 |
| Baoji Guokang Healthchem Co., Ltd. | +86-0917-3909592 +86-13892490616 | gksales1@gk-bio.com | China | 9071 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
| changzhou huayang technology co., ltd | +8615250961469 | 2571773637@qq.com | China | 9653 | 58 |
View Lastest Price from 3-isoquinolinecarboxaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-11-18 | 3-isoquinolinecarboxaldehyde
5470-80-4
|
$1.10 | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | |
 |
2021-07-13 | 3-isoquinolinecarboxaldehyde
5470-80-4
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2021-07-10 | 3-isoquinolinecarboxaldehyde
5470-80-4
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 3-isoquinolinecarboxaldehyde
5470-80-4
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 3-isoquinolinecarboxaldehyde
5470-80-4
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 3-isoquinolinecarboxaldehyde
5470-80-4
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
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