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ChemicalBook >> CAS DataBase List >>1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester

1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester

CAS No.
847818-70-6
Chemical Name:
1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester
Synonyms
1-Ethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole;1-Ethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole;1-Eth;1-Ethyl-1H-pyrazole-4-boronic acid, pina;1-Ethylpyrazole-4-boronic Acid Pinacol Ester;1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester;1-Ethyl-1H-pyrazole-4-boronic acid pinacol ester;1-ethyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole;1-Ethylpyrazole-4-boronic acid pinacol ester - [E10401];1-ethyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
CBNumber:
CB11486453
Molecular Formula:
C11H19BN2O2
Molecular Weight:
222.09
MDL Number:
MFCD09864188
MOL File:
847818-70-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 23:09:11
Product description Number Pack Size Price
1-Ethyl-1H-pyrazole-4-boronic acid pinacol ester 97% 706205 250mg $43.3
1-Ethyl-1H-pyrazole-4-boronic acid pinacol ester 97% 706205 1g $134
1-Ethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole E1348 1G $54
1-Ethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole E1348 5G $231
1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester >97% OR17569 1g $21
More product size

1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester Properties

Melting point 44-49°C
Boiling point 322.6±15.0 °C(Predicted)
Density 1.04±0.1 g/cm3(Predicted)
refractive index 1.48
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form clear liquid
pka 2.11±0.10(Predicted)
color Colorless to Almost colorless
InChI InChI=1S/C11H19BN2O2/c1-6-14-8-9(7-13-14)12-15-10(2,3)11(4,5)16-12/h7-8H,6H2,1-5H3
InChIKey UGCRHVPUHAXAAE-UHFFFAOYSA-N
SMILES N1(CC)C=C(B2OC(C)(C)C(C)(C)O2)C=N1
CAS DataBase Reference 847818-70-6
UNSPSC Code 12352103
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26
WGK Germany  3
HS Code  2933199090
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
1
2 0

1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester price More Price(65)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 706205 1-Ethyl-1H-pyrazole-4-boronic acid pinacol ester 97% 847818-70-6 250mg $43.3 2026-04-30 Buy
Sigma-Aldrich 706205 1-Ethyl-1H-pyrazole-4-boronic acid pinacol ester 97% 847818-70-6 1g $134 2026-04-30 Buy
TCI Chemical E1348 1-Ethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 847818-70-6 1G $54 2026-04-30 Buy
TCI Chemical E1348 1-Ethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 847818-70-6 5G $231 2025-07-31 Buy
Apolloscientific OR17569 1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester >97% 847818-70-6 1g $21 2026-06-04 Buy
Product number Packaging Price Buy
706205 250mg $43.3 Buy
706205 1g $134 Buy
E1348 1G $54 Buy
E1348 5G $231 Buy
OR17569 1g $21 Buy

1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester Chemical Properties,Uses,Production

Synthesis

4-Pyrazoleboronic acid pinacol ester

269410-08-4

Iodoethane

75-03-6

1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester

847818-70-6

To a solution of N,N-dimethylformamide (DMF, 10 mL) of 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (1.0 g, 5.2 mmol) was added cesium carbonate (2.5 g, 7.7 mmol) and ethyl iodide (1.2 mL, 15 mmol). The reaction mixture was stirred at room temperature for 12 hours. After the reaction was completed, the reaction mixture was diluted with water (30 mL). The aqueous phase was extracted with dichloromethane (DCM, 30 mL x 3). The organic layers were combined and dried over anhydrous sodium sulfate (Na2SO4) and subsequently concentrated under reduced pressure. The residue was purified by silica gel column chromatography using petroleum ether (PE)/ethyl acetate (EtOAc) (2:1, v/v) as eluent to afford the colorless oily product 1-ethyl-1H-pyrazole-4-boronic acid pinacol ester (880 mg, 77% yield). Mass spectrometric (MS) analysis (electrospray ionization, cation mode) showed m/z: 223.25 [M + 1]+.

References

[1] Patent: WO2016/615, 2016, A1. Location in patent: Paragraph 00655
[2] Patent: EP1798229, 2007, A1. Location in patent: Page/Page column 130
[3] Patent: US2010/240634, 2010, A1. Location in patent: Page/Page column 67-68
[4] Patent: WO2018/102452, 2018, A2. Location in patent: Paragraph 425; 426
[5] Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 19, p. 5299 - 5302

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View Lastest Price from 1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester pictures 2021-07-13 1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester
847818-70-6
$10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester pictures 2021-07-10 1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester
847818-70-6
$10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester pictures 2019-07-06 1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester
847818-70-6
$1.00 1KG 98%-100% 1 Career Henan Chemical Co

1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester Spectrum

1-ethyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester 3-hydroxy-2,3-dimethylbutan-2-yl hydrogen (1-ethyl-1H-pyrazol-4-yl)boronate 1-Ethylpyrazole-4-boronic Acid Pinacol Ester 1H-Pyrazole, 1-ethyl-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)- 1-Eth 2-(1-Ethyl-1H-pyrazol-4yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 1-Ethyl-1H-pyrazole-4-boronic acid, pina 1-ethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-p... 1-ethyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole 1-Ethyl-1H-pyrazole-4-boronic acid pinacol ester 1-Ethylpyrazole-4-boronic acid pinacol ester - [E10401] 1-Ethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole 1-Ethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 847818-70-6 C11H21BN2O3
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