BOC-CYS-OH
- CAS No.
- 20887-95-0
- Chemical Name:
- BOC-CYS-OH
- Synonyms
- BOC-L-CYS-OH;N-Boc-L-cysteine;BOC-CYS-OH;BOC-L-CYSTEINE;Boc-Cys-Cysteine;BOC-CYS-OH USP/EP/BP;N-ALPHA-T-BOC-L-CYSTEINE;Boc-Cys-OH,Boc-L-cysteine;Boc-L-cysteine≥ 98% (HPLC);Boc-Cys-OH (cryst) Novabiochem
- CBNumber:
- CB1153365
- Molecular Formula:
- C8H15NO4S
- Molecular Weight:
- 221.28
- MDL Number:
- MFCD00065565
- MOL File:
- 20887-95-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Boc-Cys-OH (cryst) Novabiochem? | 8.53031 | 5G | $283 |
| Boc-Cys-OH (cryst) Novabiochem? | 8.53031 | 25G | $982 |
| Boc-Cys-OH for chiral derivatization, ≥98.5% | 15411 | 250mg | $84 |
| Boc-Cys-OH for chiral derivatization, ≥98.5% | 15411 | 1g | $314 |
| Boc-L-cysteine | 443278 | 250mg | $333 |
| More product size | |||
| Melting point | 67-70°C |
|---|---|
| Boiling point | 361.4±37.0 °C(Predicted) |
| Density | 1+-.0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,2-8°C |
| solubility | DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol |
| pka | 3.57±0.10(Predicted) |
| form | Solid |
| color | White to Off-White |
| optical activity | [α]20/D +8.0±1.5°, c = 1% in ethanol |
| BRN | 2450705 |
| InChI | InChI=1S/C8H15NO4S/c1-8(2,3)13-7(12)9-5(4-14)6(10)11/h5,14H,4H2,1-3H3,(H,9,12)(H,10,11)/t5-/m0/s1 |
| InChIKey | ATVFTGTXIUDKIZ-YFKPBYRVSA-N |
| SMILES | C(O)(=O)[C@H](CS)NC(OC(C)(C)C)=O |
| CAS DataBase Reference | 20887-95-0(CAS DataBase Reference) |
| UNSPSC Code | 41116105 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS07,GHS08,GHS09 |
|---|---|
| Signal word | Danger |
| Hazard statements | H315-H319-H413-H372 |
| Precautionary statements | P501-P273-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
| PPE | Eyeshields, Gloves, type N95 (US) |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| HS Code | 29309090 |
| Storage Class | 13 - Non Combustible Solids |
BOC-CYS-OH price More Price(82)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.53031 | Boc-Cys-OH (cryst) Novabiochem? | 20887-95-0 | 5G | $283 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.53031 | Boc-Cys-OH (cryst) Novabiochem? | 20887-95-0 | 25G | $982 | 2023-06-20 | Buy |
| Sigma-Aldrich | 15411 | Boc-Cys-OH for chiral derivatization, ≥98.5% | 20887-95-0 | 250mg | $84 | 2022-05-15 | Buy |
| Sigma-Aldrich | 15411 | Boc-Cys-OH for chiral derivatization, ≥98.5% | 20887-95-0 | 1g | $314 | 2022-05-15 | Buy |
| Usbiological | 443278 | Boc-L-cysteine | 20887-95-0 | 250mg | $333 | 2026-06-03 | Buy |
BOC-CYS-OH Chemical Properties,Uses,Production
Chemical Properties
light yellowliquid
Uses
Boc-L-cysteine is the protected form of L-Cysteine (C995000), a non-essential α-amino acid that is biosynthesized in humans. L-Cysteine is also a bicarbonate-sensitive endogenous excitotoxin in rats and possibly humans.
reaction suitability
reaction type: Boc solid-phase peptide synthesis
Synthesis
10389-65-8
20887-95-0
General procedure for the synthesis of (R)-2-((tert-butoxycarbonyl)amino)-3-mercaptopropionic acid from N,N'-bis(Boc)-L-cystine: N,N'-bis(Boc)-L-cystine (2.51 mmol) was dissolved in a solvent mixture of tetrahydrofuran (29.2 mL) and water (0.8 mL). Tributylphosphine (2.76 mmol) was added to the solution under ice bath cooling conditions. The reaction mixture was gradually warmed up to room temperature and stirred continuously at this temperature for 1 hour. Upon completion of the reaction, ethyl acetate (20 mL) and 10% aqueous citric acid (10 mL) were added to the reaction mixture for extraction and separation. The organic phase was collected and washed with saturated aqueous saline solution (20 mL). Subsequently, the organic phase was concentrated and the resulting residue was purified by silica gel column chromatography (eluent: hexane-ethyl acetate mixed solvent) to afford the target compound 22 as an oily product. Yield: 99%. ESI MS m/z 220.1 [M-H]-; 1H NMR (400 MHz, CDCl3) δ: 5.47 (1H, brs), 4.65 (1H, brs), 3.09-2.97 (2H, m), 1.48 (9H, s).
References
[1] Patent: US2012/282386, 2012, A1. Location in patent: Page/Page column 15
[2] Journal of Nanoparticle Research, 2017, vol. 19, # 6,
[3] Angewandte Chemie, 1993, vol. 105, # 2, p. 311 - 313
[4] Chemische Berichte, 1969, vol. 102, p. 1048 - 1052
[5] Protein and Peptide Letters, 2014, vol. 21, # 12, p. 1257 - 1264
BOC-CYS-OH Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5220 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19936 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
View Lastest Price from BOC-CYS-OH manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-28 | BOC-CYS-OH
20887-95-0
|
$2.60 | 1KG | 99% | 5000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2021-08-12 | BOC-CYS-OH
20887-95-0
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2019-09-02 | BOC-CYS-OH
20887-95-0
|
$7.00 | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- BOC-CYS-OH
20887-95-0
- $2.60
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- BOC-CYS-OH
20887-95-0
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- BOC-CYS-OH
20887-95-0
- $7.00
- 99%
- Career Henan Chemical Co
