6-Fluoro-7-azaindole
- CAS No.
- 898746-42-4
- Chemical Name:
- 6-Fluoro-7-azaindole
- Synonyms
- EOS-60627;6-FLUORO-7-AZAINDOLE;2-Fluoro-1H-pyrrolo-[2,3-B]-pyridine;1H-Pyrrolo[2,3-b]pyridine, 6-fluoro-
- CBNumber:
- CB11872034
- Molecular Formula:
- C7H5FN2
- Molecular Weight:
- 136.13
- MDL Number:
- MFCD06659668
- MOL File:
- 898746-42-4.mol
| Product description | Number | Pack Size | Price |
| 6-FLUORO-1H-PYRROLO[2,3-B]PYRIDINE 97% | 52584 | 0.25G | $53 |
| 6-FLUORO-1H-PYRROLO[2,3-B]PYRIDINE 97% | 52584 | 1G | $200 |
| 6-Fluoro-7-azaindole 97% | AS17568 | 1g | $212 |
| 6-Fluoro-7-azaindole 97% | AS17568 | 5g | $954 |
| 6-Fluoro-7-azaindole | 113318 | 250.00mg | $46 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405 |
| HS Code | 2933399990 |
6-Fluoro-7-azaindole price More Price(44)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AstaTech | 52584 | 6-FLUORO-1H-PYRROLO[2,3-B]PYRIDINE 97% | 898746-42-4 | 0.25G | $53 | 2026-04-30 | Buy |
| AstaTech | 52584 | 6-FLUORO-1H-PYRROLO[2,3-B]PYRIDINE 97% | 898746-42-4 | 1G | $200 | 2026-04-30 | Buy |
| Activate Scientific | AS17568 | 6-Fluoro-7-azaindole 97% | 898746-42-4 | 1g | $212 | 2026-06-04 | Buy |
| Activate Scientific | AS17568 | 6-Fluoro-7-azaindole 97% | 898746-42-4 | 5g | $954 | 2026-06-04 | Buy |
| Matrix Scientific | 113318 | 6-Fluoro-7-azaindole | 898746-42-4 | 250.00mg | $46 | 2026-05-18 | Buy |
6-Fluoro-7-azaindole Chemical Properties,Uses,Production
Uses
7-Azaindole compounds are important pharmaceutical intermediates that can be used to synthesize a variety of drugs. 6-Fluoro-7-azaindole is a 7-azaindole compound that can be used as an intermediate for smoking cessation drugs.
Synthesis
![1H-Pyrrolo[2,3-b]pyridine-1-carboxylic acid, 6-fluoro-, ethyl ester](/CAS/GIF/1001070-28-5.gif)
1001070-28-5
898746-42-4
Compound 59 (CAS:1001070-28-5, 2.58 g, 12.4 mmol) was taken as raw material and dissolved in 50 mL of methanol and 20 mL of 2N sodium hydroxide solution. The reaction mixture was stirred at room temperature for 30 minutes. After the reaction was completed, ethyl acetate was added to the mixture for extraction. The organic layer was washed with 5% aqueous sodium bicarbonate solution and subsequently dried over anhydrous sodium sulfate. The dried organic phase was filtered and concentrated to afford 6-fluoro-1H-pyrrolo[2,3-b]pyridine (6-fluoro-7-azaindole, compound 44) as a semi-solid (1.68 g, 12.3 mmol, 99% yield). The product was confirmed by 1H-NMR (400 MHz, CDCl3): δ 9.6 (broad single peak, 1H), 7.95 (broad triple peak, J=8Hz, 1H), 7.31-7.27 (multiple peaks, 1H), 6.75 (double dichotomous peaks, J=8Hz, 2Hz, 1H), 6.55-6.50 (multiple peaks, 1H). Thin-layer chromatography (TLC) analysis showed an Rf value of 0.34 using ether/petroleum ether (1/1) as the unfolding agent.Liquid chromatography-mass spectrometry (LCMS) analysis: retention time (Rt) of 1.39 min, [M+H]+=137.
References
[1] Patent: US2008/9514, 2008, A1. Location in patent: Page/Page column 23
[2] Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 1, p. 188 - 193
6-Fluoro-7-azaindole Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| KARMEL TECHNOLOGY (HK) CO.,LIMITED | +8618795957998 | karmelhk@126.com | CHINA | 2886 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Finetech Industry Limited | +86-27-8746-5837 +8619945049750 | info@finetechnology-ind.com | China | 9539 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52704 | 58 |
