6-BROMO-4-IODOQUINOLINE
- CAS No.
- 927801-23-8
- Chemical Name:
- 6-BROMO-4-IODOQUINOLINE
- Synonyms
- 6-BROMO-4-IODOQUINOLINE;4-Iodo-6-bromoquinoline;Quinoline, 6-bromo-4-iodo-;6-Bromo-4-iodoquinoline 97%
- CBNumber:
- CB1222641
- Molecular Formula:
- C9H5BrIN
- Molecular Weight:
- 333.95
- MDL Number:
- MFCD08437008
- MOL File:
- Mol file
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 6-Bromo-4-iodoquinoline 97% | OR927338 | 250mg | $32 |
| 6-Bromo-4-iodoquinoline 97% | OR927338 | 1g | $98 |
| 6-Bromo-4-iodoquinoline 97% | OR927338 | 5g | $408 |
| 6-Bromo-4-iodoquinoline 97% | OR927338 | 250mg | $32 |
| 6-Bromo-4-iodoquinoline 97% | OR927338 | 1g | $98 |
| Boiling point | 375.5±22.0 °C(Predicted) |
|---|---|
| Density | 2.154±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C(protect from light) |
| form | solid |
| pka | 2.77±0.16(Predicted) |
| color | Brown |
| InChI | InChI=1S/C9H5BrIN/c10-6-1-2-9-7(5-6)8(11)3-4-12-9/h1-5H |
| InChIKey | BWFLFNVNIISPPK-UHFFFAOYSA-N |
| SMILES | N1C2C(=CC(Br)=CC=2)C(I)=CC=1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P280-P305+P351+P338-P310 |
| HS Code | 2933491090 |
6-BROMO-4-IODOQUINOLINE price More Price(59)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR927338 | 6-Bromo-4-iodoquinoline 97% | 927801-23-8 | 250mg | $32 | 2026-06-04 | Buy |
| Apolloscientific | OR927338 | 6-Bromo-4-iodoquinoline 97% | 927801-23-8 | 1g | $98 | 2026-06-04 | Buy |
| Apolloscientific | OR927338 | 6-Bromo-4-iodoquinoline 97% | 927801-23-8 | 5g | $408 | 2026-06-04 | Buy |
| Apolloscientific | OR927338 | 6-Bromo-4-iodoquinoline 97% | 927801-23-8 | 250mg | $32 | 2026-06-04 | Buy |
| Apolloscientific | OR927338 | 6-Bromo-4-iodoquinoline 97% | 927801-23-8 | 1g | $98 | 2026-06-04 | Buy |
6-BROMO-4-IODOQUINOLINE Chemical Properties,Uses,Production
Synthesis
1086062-75-0
927801-23-8
4.1.9 Synthesis of 6-bromo-4-iodoquinoline (12): To an anhydrous ethyl acetate (20 mL) solution of 6-bromo-4-chloroquinoline (11) (3.50 g, 14.46 mmol) was added hydrochloric acid saturated ethyl acetate (40 mL), and the formation of a white precipitate was immediately observed. After stirring for 30 min, the suspension was concentrated under vacuum to give 6-bromo-4-chloroquinoline hydrochloride as an off-white solid (3.91 g, 14.14 mmol). Subsequently, 6-bromo-4-chloroquinoline hydrochloride (3.91 g, 14.14 mmol), anhydrous potassium iodide (9.76 g, 70.70 mmol), and anhydrous acetonitrile (100 mL) were added in a two-neck flask. The resulting slurry was stirred under reflux conditions for 48 hours and then cooled to room temperature. The reaction mixture was treated with saturated aqueous sodium bicarbonate solution (40 mL) and 5% sodium sulfite solution (20 mL). The reaction mixture was extracted with dichloromethane (200 mL x 2), and the combined organic phases were dried over magnesium sulfate and concentrated under vacuum to give the crude product. The crude product was further purified by silica gel column chromatography (25% ethyl acetate/petroleum ether) to afford the target compound 6-bromo-4-iodoquinoline (4.42 g, 13.27 mmol, 94% yield) as an off-white solid. 1H NMR (500 MHz, DMSO-d6) δ 8.51 (d, J = 4.5 Hz, 1H, Ar-H), 8.21 (d, J = 4.5 Hz, 1H, Ar-H), 8.11 (t, J = 1.5 Hz, 1H, Ar-H), 7.97-7.91 (m, 2H, Ar-H). ESI-MS: m/z = 334 [M + H]+.
References
[1] European Journal of Medicinal Chemistry, 2015, vol. 99, p. 36 - 50
[2] RSC Advances, 2017, vol. 7, # 4, p. 2342 - 2350
[3] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 4, p. 1569 - 1574
[4] Patent: WO2014/22128, 2014, A1. Location in patent: Paragraph 0156; 0157
[5] Patent: CN103539777, 2016, B. Location in patent: Paragraph 0276; 0327; 0328
6-BROMO-4-IODOQUINOLINE Preparation Products And Raw materials
6-BROMO-4-IODOQUINOLINE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14304 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
| Changzhou AniKare Pharmatech Co., Ltd. | +86-0519-8359-8696 +8618018249389 | sales@anikare.com | China | 9981 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43333 | 58 |
| Sichuan Biosynce Pharmatech Co., Ltd. | +8619950309693 | diane@biosynce.com | China | 4871 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Hebei Fengmu Trading Co., Ltd. | +8613393234347 | Lyla@fengmuchem.com | China | 2943 | 58 |
View Lastest Price from 6-BROMO-4-IODOQUINOLINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-03 | 6-BROMO-4-IODOQUINOLINE
927801-23-8
|
$1.00 | 1KG | 95-99% | 1ton | Career Henan Chemical Co |
-
- 6-BROMO-4-IODOQUINOLINE
927801-23-8
- $1.00
- 95-99%
- Career Henan Chemical Co
