ChemicalBook >> CAS DataBase List >>(2S,4R)-methyl 4-hydroxypyrrolidine-2-carboxylate hydrochloride
(2S,4R)-methyl 4-hydroxypyrrolidine-2-carboxylate hydrochloride
- CAS No.
- 481704-21-6
- Chemical Name:
- (2S,4R)-methyl 4-hydroxypyrrolidine-2-carboxylate hydrochloride
- Synonyms
- H-D-trans-Hyp-OMe.HCl;Methyl (2R,4S)-4-hydroxypyrrolidine-2-carboxylate hydrochloride;(2R,4S);H-D-Hyp-OMe.HCl;Trans-4-HYDROXY-D-PROLINE METHYL ESTER;(S)-4-HYDROXY-D-PROLINE METHYL ESTER HCL;(4S)-D-Proline-4-hydroxyMethylester hydrochloride;D-Proline-4-hydroxyMethylester hydrochloride (4S);(S)-4-Hydroxy-D-proline Methyl Ester Hydrochloride;(4S)-4-Hydroxy-D-proline Methyl ester hydrochloride
- CBNumber:
- CB12470822
- Molecular Formula:
- C6H12ClNO3
- Molecular Weight:
- 181.62
- MDL Number:
- MFCD00135747
- MOL File:
- 481704-21-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-27 23:16:40
| Product description | Number | Pack Size | Price |
| Methyl (2R,4S)-4-hydroxypyrrolidine-2-carboxylate hydrochloride Asreported | 284714 | 50mg | $343 |
| Methyl (2R,4S)-4-hydroxypyrrolidine-2-carboxylate hydrochloride Asreported | 284714 | 100mg | $472 |
| Methyl (2R,4S)-4-hydroxypyrrolidine-2-carboxylate hydrochloride Asreported | 284714 | 250mg | $573 |
| Methyl (2R,4S)-4-hydroxypyrrolidine-2-carboxylate hydrochloride Asreported | 284714 | 500mg | $758 |
| Methyl (2R,4S)-4-hydroxypyrrolidine-2-carboxylate hydrochloride Asreported | 284714 | 1g | $1002 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312+H332-H315-H319-H335 |
| Precautionary statements | P261-P271-P280 |
| HS Code | 2933998090 |
(2S,4R)-methyl 4-hydroxypyrrolidine-2-carboxylate hydrochloride price More Price(88)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 284714 | Methyl (2R,4S)-4-hydroxypyrrolidine-2-carboxylate hydrochloride Asreported | 481704-21-6 | 50mg | $343 | 2026-06-03 | Buy |
| Usbiological | 284714 | Methyl (2R,4S)-4-hydroxypyrrolidine-2-carboxylate hydrochloride Asreported | 481704-21-6 | 100mg | $472 | 2026-06-03 | Buy |
| Usbiological | 284714 | Methyl (2R,4S)-4-hydroxypyrrolidine-2-carboxylate hydrochloride Asreported | 481704-21-6 | 250mg | $573 | 2026-06-03 | Buy |
| Usbiological | 284714 | Methyl (2R,4S)-4-hydroxypyrrolidine-2-carboxylate hydrochloride Asreported | 481704-21-6 | 500mg | $758 | 2026-06-03 | Buy |
| Usbiological | 284714 | Methyl (2R,4S)-4-hydroxypyrrolidine-2-carboxylate hydrochloride Asreported | 481704-21-6 | 1g | $1002 | 2026-06-03 | Buy |
(2S,4R)-methyl 4-hydroxypyrrolidine-2-carboxylate hydrochloride Chemical Properties,Uses,Production
Uses
(4S)-4-Hydroxy-D-proline methyl ester, HCl
Synthesis
3398-22-9
481704-21-6
(2R,4S)-4-hydroxypyrrolidine-2-carboxylic acid (1; 10 g, 76.3 mmol) was used as raw material and dissolved in 200 mL of methanol. Under stirring conditions, acetyl chloride (7.6 mL, 106.8 mmol) was slowly added, followed by heating the reaction mixture to reflux overnight. Upon completion of the reaction, the mixture was cooled to room temperature and 500 mL of ether was added to induce crystallization. The white crystals formed were collected by filtration and dried under vacuum to ultimately afford methyl (2R,4S)-4-hydroxypyrrolidine-2-carboxylate hydrochloride (Compound 2; 12.7 g, 87.6% yield).
IC 50
Non-cleavable Linker
References
[1] Patent: WO2003/104249, 2003, A1. Location in patent: Page 14
(2S,4R)-methyl 4-hydroxypyrrolidine-2-carboxylate hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 114)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chembon Pharmaceutical Co., Ltd. | +86-28-8425-2981 | CHINA | 722 | 55 | |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Chengdu Pukang Biotechnology Co., Ltd | 028-82550498 | export@pu-kang.com | CHINA | 210 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| GL Biochem(Binhai) Ltd. | +86-021-61263370 +8615301650015 | wuqiuyan@glschina.com | China | 2975 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 20582 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
View Lastest Price from (2S,4R)-methyl 4-hydroxypyrrolidine-2-carboxylate hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-12-23 | (2R,4S)-Methyl 4-hydroxypyrrolidine-2-carboxylatehydrochloride
481704-21-6
|
$2.00 | 1KG | ≥98% | 100kg | Career Henan Chemical Co |
-
- (2R,4S)-Methyl 4-hydroxypyrrolidine-2-carboxylatehydrochloride
481704-21-6
- $2.00
- ≥98%
- Career Henan Chemical Co
(2S,4R)-Methyl 4-hydro×ypyrrolidine-2-carbo×ylate hydrochloride
(4S)-4-Hydroxy-D-proline Methyl ester hydrochloride
(4S)-D-Proline-4-hydroxyMethylester hydrochloride
(S)-4-Hydroxy-D-proline Methyl Ester Hydrochloride
D-Proline-4-hydroxyMethylester hydrochloride (4S)
trans-4-Hydroxy-D-proline methyl ester hydrochloride, (2R,4S)-4-Hydroxy-2-(methoxycarbonyl)pyrrolidine hydrochloride
D-Proline, 4-hydroxy-, Methyl ester, hydrochloride (1:1), (4S)-
4-hydroxy-1-Methylpyrrolidine-2-carboxylate hydrochloride
(2R,4S)
(S)-4-HYDROXY-D-PROLINE METHYL ESTER HCL
(2R,4S)-trans-4-hydroxy-D-proline methyl ester hydrochloride
(2S,4R)-4-Hydroxy-2-(methoxycarbonyl)pyrrolidinium chloride
TRANS-4-HYDROXY-D-PROLINE METHYL ESTER HYDROCHLORIDE
(2S,4R)-methyl 4-hydroxypyrrolidine-2-carboxylate hydrochloride USP/EP/BP
tans-4-Hydroxy-D-proline methyl ester (hydrochloride)
(2S,4R)-methyl 4-hydroxypyrrolidine-2-carboxylate hydrochlorid
rans-4-Hydroxy-D-proline methyl ester hydrochloride
(4S)-4-hydroxy-D-Proline methyl ester hydrochloride (1:1)
(2R,4S)-methyl 4-hydroxypyrrolidine-2-carboxylate hydrochloride H-Hyp-OMe.HCl
Trans-4-HYDROXY-D-PROLINE METHYL ESTER
H-D-Hyp-OMe.HCl
(2R,4S)-methyl 4-hydroxypyrrolidine-2-carboxylate Hydrochloride/Trans-4-HYDROXY-D-PROLINE METHYL ESTER Hydrochloride
H-D-trans-Hyp-OMe.HCl
Methyl (2R,4S)-4-hydroxypyrrolidine-2-carboxylate hydrochloride
481704-21-6
