ChemicalBook >> CAS DataBase List >>5-Difluoromethoxy-2-{[(3,4-dimethoxy-2-pyridinyl)methyl]thio}-1H-benzimidazole
5-Difluoromethoxy-2-{[(3,4-dimethoxy-2-pyridinyl)methyl]thio}-1H-benzimidazole
![5-Difluoromethoxy-2-{[(3,4-dimethoxy-2-pyridinyl)methyl]thio}-1H-benzimidazole Structure](CAS/GIF/102625-64-9.gif)
- CAS No.
- 102625-64-9
- Chemical Name:
- 5-Difluoromethoxy-2-{[(3,4-dimethoxy-2-pyridinyl)methyl]thio}-1H-benzimidazole
- Synonyms
- PANTOPRAZOLE SULFIDE;Pantoprazole Related CoMpound B;5-(DifluoroMethoxy)-2-(((3,4-diMethoxypyridin-2-yl)Methyl)thio)-1H-benzo[d]iMidazole;Pantoprazole-2;pantoprazole sulphide;Pantoprazole Ep Imp B;Pantoprazole Thioether;PantoprazoleSulfide>5-DifluoroMethoxy-2-[(3;Pantoprazole condensate
- CBNumber:
- CB1253016
- Molecular Formula:
- C16H15F2N3O3S
- Molecular Weight:
- 367.37
- MDL Number:
- MFCD07368273
- MOL File:
- 102625-64-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-27 23:20:17
| Product description | Number | Pack Size | Price |
| Pantoprazole Related Compound B pharmaceutical secondary standard, certified reference material | PHR3074 | 50MG | $382 |
| Pantoprazole Related Compound B United States Pharmacopeia (USP) Reference Standard | 1494910 | 25mg | $1390 |
| Pantoprazole Sulfide >98.0%(HPLC)(T) | P2066 | 1g | $25 |
| Pantoprazole Sulfide >98.0%(HPLC)(T) | P2066 | 5g | $76 |
| Pantoprazole Sulfide ≥98% | 22251 | 1g | $36 |
| More product size | |||
| Melting point | 110-118°C |
|---|---|
| Boiling point | 526.3±60.0 °C(Predicted) |
| Density | 1.43±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 8.97±0.10(Predicted) |
| color | Off-White to Light Brown |
| BRN | 5358607 |
| Major Application | pharmaceutical |
| InChI | InChI=1S/C16H15F2N3O3S/c1-22-13-5-6-19-12(14(13)23-2)8-25-16-20-10-4-3-9(24-15(17)18)7-11(10)21-16/h3-7,15H,8H2,1-2H3,(H,20,21) |
| InChIKey | UKILEIRWOYBGEJ-UHFFFAOYSA-N |
| SMILES | C1(SCC2=NC=CC(OC)=C2OC)NC2=CC(OC(F)F)=CC=C2N=1 |
| CAS DataBase Reference | 102625-64-9(CAS DataBase Reference) |
| FDA UNII | BWZ6X03HIB |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| WGK Germany | WGK 3 | |||||||||
| HS Code | 2933399090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| REACH Registrations | Inactive | |||||||||
| NFPA 704 |
|
5-Difluoromethoxy-2-{[(3,4-dimethoxy-2-pyridinyl)methyl]thio}-1H-benzimidazole price More Price(91)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHR3074 | Pantoprazole Related Compound B pharmaceutical secondary standard, certified reference material | 102625-64-9 | 50MG | $382 | 2026-04-30 | Buy |
| Sigma-Aldrich | 1494910 | Pantoprazole Related Compound B United States Pharmacopeia (USP) Reference Standard | 102625-64-9 | 25mg | $1390 | 2026-04-30 | Buy |
| TCI Chemical | P2066 | Pantoprazole Sulfide >98.0%(HPLC)(T) | 102625-64-9 | 1g | $25 | 2026-04-30 | Buy |
| TCI Chemical | P2066 | Pantoprazole Sulfide >98.0%(HPLC)(T) | 102625-64-9 | 5g | $76 | 2026-04-30 | Buy |
| Cayman Chemical | 22251 | Pantoprazole Sulfide ≥98% | 102625-64-9 | 1g | $36 | 2026-04-30 | Buy |
5-Difluoromethoxy-2-{[(3,4-dimethoxy-2-pyridinyl)methyl]thio}-1H-benzimidazole Chemical Properties,Uses,Production
Chemical Properties
Beige Solid
Uses
Pantoprazole Sulfide (Pantoprazole EP Impurity B) is a metabolite of Pantoprazole (P183000), an antiulcerative, gastric pump inhibitor.
Uses
A metabolite of Pantoprazole, an antiulcerative, gastric pump inhibitor
Synthesis
169905-10-6
97963-62-7
![5-Difluoromethoxy-2-{[(3,4-dimethoxy-2-pyridinyl)methyl]thio}-1H-benzimidazole](/CAS/GIF/102625-64-9.gif)
102625-64-9
[Example 1] Preparation of 5-(difluoromethoxy)-2-(((3,4-dimethoxypyridin-2-yl)methyl)thio)-1H-benzo[d]imidazole: 920 mL of isopropanol, 92.1 g of 5-difluoromethoxy-2-mercapto-1H-benzimidazole, and 95.8 g of 2-chloromethyl-3,4-dimethoxypyridine were added to the reactor. Sodium hydroxide solution (prepared by dissolving 20.5 g of sodium hydroxide in 920 mL of pure water) was added slowly and dropwise to the above mixture, followed by stirring the reaction mixture for 2 hours at room temperature. Upon completion of the reaction, 920 mL of pure water was added to the mixture and stirring was continued for 1 hour. The resulting solid product was collected by filtration and dried under vacuum to give 137.4 g of the target compound in 87.8% yield with a melting point of 94 °C.
References
[1] Patent: WO2009/75516, 2009, A2. Location in patent: Page/Page column 4
[2] Organic Process Research and Development, 2013, vol. 17, # 10, p. 1272 - 1276
5-Difluoromethoxy-2-{[(3,4-dimethoxy-2-pyridinyl)methyl]thio}-1H-benzimidazole Preparation Products And Raw materials
Global( 416)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21586 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6366 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19936 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Qiuxian Baitai New Material Co., LTD | +8618330912755 | sale2@hbyalin.com | China | 1658 | 58 |
View Lastest Price from 5-Difluoromethoxy-2-{[(3,4-dimethoxy-2-pyridinyl)methyl]thio}-1H-benzimidazole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-11-23 | Pantoprazole sulfide
102625-64-9
|
$35.00 | 500KG | ≥98% | 100tons | Qiuxian Baitai New Material Co., LTD | |
 |
2021-07-13 | Pantoprazole Sulfide
102625-64-9
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2021-07-10 | Pantoprazole Sulfide
102625-64-9
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- Pantoprazole sulfide
102625-64-9
- $35.00
- ≥98%
- Qiuxian Baitai New Material Co., LTD
-
- Pantoprazole Sulfide
102625-64-9
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- Pantoprazole Sulfide
102625-64-9
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
102625-64-9(5-Difluoromethoxy-2-{[(3,4-dimethoxy-2-pyridinyl)methyl]thio}-1H-benzimidazole)Related Search:
1of4
Pantoprazole Related Compound B (25 mg) (5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]thio]-1H-benzimidazole)
Pantoprazole Thioether
5-(DIFLUOROMETHOXY)-2-[[3,4-DIMETHOXY-2-PYRIDINYL)-METHYL]-THIO]-1H- BENZIMIDAZOLE (PANTOPRAZOLE SULPHIDE COMPOUND)
Pantoprazole Thioether, 5-(Difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]thio]-1H-benzimidazole
5-(Difluoromethoxy)-2-{[3,4-di
5-Difluoromethoxy-2-{[(3,4-dim
5-(DIFLUOROMETHOXY)-2-{[3,4-DIMETHOXY-2-PYRIDINYL)METHYL]THIO}IH- BENZIMIDAZOLE
5-Difluoromethoxy-2-(((3,4-Dimethoxy-2-pyridinyl)methyl)thio)-1H-Benzimidazole (Pantaprazole intermediate)
5-(Difluoromethoxy)-2-{[(3,4-dimethoxy-2-pyridinyl)-methyl]-thio}-1H-benzim
5-DIFLUOROMETHOXY-2-[(3,4-DIMETHOXY-2-PYRIDINYL)METHYL] THIO-1H-BENZIMIDAZOLE =98%
5-DIFLUORMETHOXY-2[(3,4-DIMETHOXY-2-PRIDIXY)METHYLTHIO]-1H-BENZIMIDAZOLE
5-(Difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]thio}-1H-benzimidazole
5-Difluoromethoxy-2-(3,4-dimethoxy-pyridin-2-ylmethylsulfanyl)-1H-benzoimidazole
5-(Difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]sulphanyl}-1H-benzimidazole
4-diMethoxy-2-pyridinyl)Methyl]thio-1H-benziMidazole
5-DifluoroMethoxy-2-[(3
Pantoprazole EP IMpurity-B (USP RC B)
5-DIFLUOROMETHOXY-2-[(3,4-DIMETHOXY-2-PYRIDINYL)METHYL]THIO-1H-BENZIMIDAZOLE
PANTOPRAZOLE SULFIDE
Pantoprazole EP IMpurity B
5-DifluoroMethoxy-2-[(3,4-diMethoxy-2-pyridyl)Methyl]thio-1H-benziMidazole, 95%
Pantoprazole Sulfide (Pantoprazole IMpurity B)
5-(Difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridiny)-methyl]thio]-1H-benzimidazole
1H-BenziMidazole,6-(difluoroMethoxy)-2-[[(3,4-diMethoxy-2-pyridinyl)Methyl]thio]-
Pantoprazole Sodium Hydrate Impurity
pantoprazole sulphide
Pantoprazole Related CoMpound
Pantoprazole Sodium impurity
5-(Difluoromethoxy)-2- {[( 3,4 Dimethoxypyridin - 2- yl) methyl] thio}-1H-benzimidazolee
5-DIFLUOROMETHOXY-2-[(3,4-DIMETHOXY-2-PYRIDINYL)METHYL]THIO-1H-BENZIMIDAZOLE
Pantoprazole Impurity 2(Pantoprazole EP Impurity B)
Pantoprazole Sulphide Compound
Pantoprazole Ep Imp B
Pantoprazole-2
Pantoprazole EP Impurity B (Pantoprazole Sulfide)
Pantoprazole sodium impurity B
PantoprazoleSulfide>
Pantoprazole Sulfur ether
5-(Difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridyl)methyl]thio]benzimidazole
5-(Difluoromethoxy)-2-
[[(3,4-dimethoxy-2-
pyridinyl)-2-methyl]thio]-
1H-benzimidazole
5-(Difluoromethoxy)-2-{[(3,4Dimethoxy pyridin-2-
yl)methyl]thio}-1h-Benzimidazole(PantoSulphide)
Pantoprazole EP Impurity B/ Pantoprazole Related Compound B (Pantoprazole Sulfide)
Pantoprazole SulphideQ: What is
Pantoprazole Sulphide Q: What is the CAS Number of
Pantoprazole Sulphide Q: What is the storage condition of
Pantoprazole Sulphide Q: What are the applications of
Pantoprazole Sulphide
Pantoprazole Related Compound B (5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]thio]-1H (1494910)
PantoprazoleEPImpurityB-d6
5-Difluoromethoxy-2-H[(3,4-dimethoxy-2-pyridinyl)methyl]thio}-1H-
benzimidazole
Pantoprazole USP Related Compound B
5-(Difluoro methoxy)-2-{[(3,4 dimethoxypyridin-2-yl)methyl]thio}-1H-benzimidazole (Panto Sulfide)
5-(difluoromethoxy)-2-[[(3,4-dimethoxypyridin-2-yl)methyl]sulfanyl]-1H-benzimidazole
5-(Difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2- yl)methyl]thio}-1H-benzimidazole?(SULPHIIDE)
Pantoprazole Sodium EP Impurity B
5-(Difluromethoxy)-2-{[(3,4-dimethoxy-2-pyridinyl)methyl]thio}-1H-Benzimidazole(pantoprazole sulfide)
5-Difluoromethoxy-2 {[(3,4-dimethyl-2-pyridyl) methyl] sulfur}-1H-benzimidazole
Pantoprazole condensate
Pantoprazole Sulfide, ≥ 98.0%
Pantoprazole EP Impurity B
Pantoprazole Related Compound B
Pantoprazole sulfide in methanol
Pantoprazole Sodium Sesquihydrate EP Impurity B
Pantoprazole USP Related Compound-B / Pantoprazole EP Impurity-B (Sulfide)
