1-Cyclohexylpiperazine
- CAS No.
- 17766-28-8
- Chemical Name:
- 1-Cyclohexylpiperazine
- Synonyms
- AKOS BBS-00003612;BUTTPARK 82\06-06;TIMTEC-BB SBB003875;Avatopal impurity 47;N-Cyclohexylpiperazine;1-Cyclohexylpiperizine;1-CYCLOHEXYLPIPERAZINE;Avatrombopag Impurity 9;Piperazine, 1-cyclohexyl-;Avatroposide impurities15
- CBNumber:
- CB1309032
- Molecular Formula:
- C10H20N2
- Molecular Weight:
- 168.28
- MDL Number:
- MFCD00044809
- MOL File:
- 17766-28-8.mol
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 1-Cyclohexylpiperazine >98.0%(GC)(T) | C1783 | 5g | $42 |
| 1-Cyclohexylpiperazine >98.0%(GC)(T) | C1783 | 25g | $126 |
| 1-Cyclohexylpiperazine Asreported | 270381 | 10g | $363 |
| 1-Cyclohexylpiperazine Asreported | 270381 | 25g | $582 |
| 1-Cyclohexylpiperazine Asreported | 270381 | 50g | $811 |
| More product size | |||
| Melting point | 28-32 °C |
|---|---|
| Boiling point | 287.25°C (rough estimate) |
| Density | 0.9725 (rough estimate) |
| refractive index | 1.6011 |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Low Melting Solid |
| pka | 9.25±0.10(Predicted) |
| color | Yellow-brownish |
| BRN | 106845 |
| InChI | InChI=1S/C10H20N2/c1-2-4-10(5-3-1)12-8-6-11-7-9-12/h10-11H,1-9H2 |
| InChIKey | XPDSXKIDJNKIQY-UHFFFAOYSA-N |
| SMILES | N1(C2CCCCC2)CCNCC1 |
| CAS DataBase Reference | 17766-28-8(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 24/25-26 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 29335990 | |||||||||
| NFPA 704 |
|
1-Cyclohexylpiperazine price More Price(59)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | C1783 | 1-Cyclohexylpiperazine >98.0%(GC)(T) | 17766-28-8 | 5g | $42 | 2026-04-30 | Buy |
| TCI Chemical | C1783 | 1-Cyclohexylpiperazine >98.0%(GC)(T) | 17766-28-8 | 25g | $126 | 2026-04-30 | Buy |
| Usbiological | 270381 | 1-Cyclohexylpiperazine Asreported | 17766-28-8 | 10g | $363 | 2026-06-03 | Buy |
| Usbiological | 270381 | 1-Cyclohexylpiperazine Asreported | 17766-28-8 | 25g | $582 | 2026-06-03 | Buy |
| Usbiological | 270381 | 1-Cyclohexylpiperazine Asreported | 17766-28-8 | 50g | $811 | 2026-06-03 | Buy |
1-Cyclohexylpiperazine Chemical Properties,Uses,Production
Chemical Properties
yellow-brownish low melting solid
Uses
1-Cyclohexylpiperazine is an σ1 and σ2 receptor ligands with diagnostic and therapeutic potentials.
Synthesis Reference(s)
Tetrahedron Letters, 35, p. 7331, 1994 DOI: 10.1016/0040-4039(94)85306-1
Materials Uses
1-Cyclohexylpiperazine can be used to develop new luminescent materials such as [CYP]ZnBr4 (CYP = 1-cyclohexylpiperazine). It is a highly efficient blue luminescent lead-free halide material with high luminous efficiency (photoluminescence quantum yield up to 79.22%) and stability, which can be used to manufacture highly efficient blue phosphors for white light-emitting diodes (LEDs) [1].
Synthesis
1224935-95-8
17766-28-8
General procedure for the synthesis of 1-cyclohexylpiperazine from tert-butyl 4-cyclohexylpiperazine-1-carboxylate: tert-butyl 4-cyclohexylpiperazine-1-carboxylate (1.38 g, 5.15 mmol) was dissolved in a mixture of ethanol/hydrochloric acid (15 mL), and the reaction was stirred for 18 h at room temperature. After completion of the reaction, the solvent was removed by distillation under reduced pressure. To the residue, 5 mL of water was added and the aqueous phase was washed with ethyl acetate (5 mL × 3). Subsequently, the aqueous phase was adjusted to pH 7~8 with base and extracted with ethyl acetate (10 mL × 3). All organic phases were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure to give 0.78 g of 1-cyclohexylpiperazine (confirmed by LC-MS and TLC, yield: 90.1%).
References
[1] Wang, Yu-Yin et al. “High Emission Efficiency and Thermal Stability in Zero-Dimensional Hybrid Zinc Halide as a Blue Light Emitter.” Inorganic chemistry vol. 62,38 (2023): 15711-15718. doi:10.1021/acs.inorgchem.3c02313
1-Cyclohexylpiperazine Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Senova Technology Co. Ltd. | +86-0755-86703119 +8618503098836 | info@senovatech.com | China | 351 | 58 |
| Rongchuang International | +8613175533356 | kevin@rongchuangintl.com | China | 272 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Anhui Dexinjia Biopharm Co., Ltd | +86-531-82375818 +86-15064153060 | sales01@jndxj.com | China | 296 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88298848 | info@edengenechem.com | China | 2165 | 58 |
| BTC Nantong Pharmaceuticals Technology Co.,Ltd | +86-0513-81283365 | Info@btcpharm.com | China | 251 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
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View Lastest Price from 1-Cyclohexylpiperazine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-04 | 1-Cyclohexylpiperazine
17766-28-8
|
1g | 99% | 9999 | Rongchuang International | ||
 |
2026-05-18 | 1-Cyclohexylpiperazine
17766-28-8
|
$100.00-2000.00 | 98% | 2MT per month | Anhui Dexinjia Biopharm Co., Ltd | ||
 |
2025-12-15 | 1-Cyclohexylpiperazine
17766-28-8
|
1kg | ＞99% by GC | 50kg | Zison Pharmaceutical (Shandong) Co., Ltd. |
-
- 1-Cyclohexylpiperazine
17766-28-8
- $0.00
- 99%
- Rongchuang International
-
- 1-Cyclohexylpiperazine
17766-28-8
- $100.00-2000.00
- 98%
- Anhui Dexinjia Biopharm Co., Ltd
-
- 1-Cyclohexylpiperazine
17766-28-8
- ＞99% by GC
- Zison Pharmaceutical (Shandong) Co., Ltd.
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