1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose
- CAS No.
- 18968-05-3
- Chemical Name:
- 1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose
- Synonyms
- 1,3,4,6-Tetra-O<;beta-D-Mannopyranose tetraacetate;1,3,4,6-Tetra-O-acetyl-ββ-D-Mannopyranose 1,3,4,6-tetraacetate;1,3,4,6-Tetraacetate β-D-Mannopyranose;1,3,4,6-Tetra-O-acetyl-β-D-maopyranose;1,3,4,6-Tetra-O-acetyl-?D-mannopyranose;1,3,4,6-O-Tetraacetyl-β-D-Mannopyranose;β-d-mannopyranose 1,3,4,6-tetra-o-acetate;1,3,4,6-TETRA-O-ACETYL-SS-D-MANNOPYRANOSE
- CBNumber:
- CB1361140
- Molecular Formula:
- C14H20O10
- Molecular Weight:
- 348.3
- MDL Number:
- MFCD00012354
- MOL File:
- 18968-05-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose 98% | 310247 | 100mg | $170 |
| 1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose >97.0%(GC) | T1459 | 1g | $118 |
| 1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose >97.0%(GC) | T1459 | 5g | $355 |
| 1,3,4,6-Tetra-O-acetyl-b-D-mannopyranose | MT02170 | 0.002kg | $200.62 |
| 1,3,4,6-Tetra-O-acetyl-b-D-mannopyranose | MT02170 | 0.005kg | $334.36 |
| More product size | |||
| Melting point | 160-161 °C(lit.) |
|---|---|
| Boiling point | 425.5±45.0 °C(Predicted) |
| Density | 1.33±0.1 g/cm3(Predicted) |
| refractive index | -22.5 ° (C=1.4, CHCl3) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | very faint turbidity in Chloroform |
| form | powder to crystal |
| pka | 12.22±0.70(Predicted) |
| color | White to Almost white |
| optical activity | [α]19/D 68°, c = 0.7 in pyridine |
| BRN | 96634 |
| InChI | InChI=1/C14H20O10/c1-6(15)20-5-10-12(21-7(2)16)13(22-8(3)17)11(19)14(24-10)23-9(4)18/h10-14,19H,5H2,1-4H3/t10-,11+,12-,13-,14-/s3 |
| InChIKey | SHBHJRVMGYVXKK-XVIXHAIJSA-N |
| SMILES | [C@@H]1(OC(=O)C)[C@@H](COC(=O)C)O[C@@H](OC(=O)C)[C@@H](O)[C@H]1OC(=O)C |&1:0,5,12,17,19,r| |
| CAS DataBase Reference | 18968-05-3(CAS DataBase Reference) |
| UNSPSC Code | 12352201 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| PPE | Eyeshields, Gloves, type N95 (US) |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| HS Code | 29400090 |
| Storage Class | 11 - Combustible Solids |
1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose price More Price(65)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 310247 | 1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose 98% | 18968-05-3 | 100mg | $170 | 2026-04-30 | Buy |
| TCI Chemical | T1459 | 1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose >97.0%(GC) | 18968-05-3 | 1g | $118 | 2026-04-30 | Buy |
| TCI Chemical | T1459 | 1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose >97.0%(GC) | 18968-05-3 | 5g | $355 | 2026-04-30 | Buy |
| Biosynth | MT02170 | 1,3,4,6-Tetra-O-acetyl-b-D-mannopyranose | 18968-05-3 | 0.002kg | $200.62 | 2026-06-04 | Buy |
| Biosynth | MT02170 | 1,3,4,6-Tetra-O-acetyl-b-D-mannopyranose | 18968-05-3 | 0.005kg | $334.36 | 2026-06-04 | Buy |
1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose Chemical Properties,Uses,Production
Uses
1,3,4,6-Tetra-o-acetyl-beta-d-mannopyranose is an intermediate in the preparation of precursors of 2-[18F]fluoro-2-deoxy-D-glucose for diagnostic use in positron emission tomography.
Synthesis
28140-37-6
18968-05-3
General procedure for the synthesis of (2S,3S,4R,5R,6R)-6-(acetyloxymethyl)-3-hydroxytetrahydro-2H-pyran-2,4,5-triyl triacetate from 1,2-O-(1-ethoxyethylidene)-β-D-mannopyranose triacetate: to a solution of anhydrous acetone (27 mL) of the protoacid ester (4.4 g, 12 mmol), a slow addition of a 1 M aqueous hydrochloric acid (HCl) solution (2.7 mL), and the reaction was carried out under vigorous stirring (the water bath temperature was maintained at about 18 °C). The reaction mixture was continued to be stirred at room temperature for 5 min before being concentrated on a rotary evaporator, keeping the temperature below 20 °C. The concentrated solid was dissolved in chloroform (CHCl3, 25 mL) and washed with deionized water (2 x 10 mL). The organic phase was dried over anhydrous sodium sulfate (Na2SO4) and filtered, and the filtrate was concentrated on a rotary evaporator. The residue was ground with ether (Et2O) and recrystallized from ethanol (EtOH) to give the target product tetraacetylmannose (1.9 g, 45% yield) as a white solid. Thin layer chromatography (TLC) Rf value was 0.13 (unfolding agent: hexane/ethyl acetate = 1:1). The melting point is 134-136°C. High Resolution Mass Spectrometry (HRMS-ESI): m/z C14H20NaO10 ([M+Na]+) Calculated value 371.09542, measured value 371.09581 (error 0.39 mmu, 1.06 ppm).
References
[1] Bioorganic and Medicinal Chemistry, 2018, vol. 26, # 8, p. 1848 - 1858
[2] Tetrahedron, 1992, vol. 48, # 47, p. 10249 - 10264
[3] Tetrahedron Letters, 2013, vol. 54, # 17, p. 2190 - 2193
1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Beijing Ribio Biotech Co.,Ltd | 010-62664360 +8613328773880 | wucy@ribio.com.cn | China | 117 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13901 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Jinan Samuel Pharmaceutical CO., Ltd | 0531-88821801 15192360884 | 605818151@qq.com | CHINA | 124 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Yunbio Tech Co.,Ltd. | +86-010-60605551 +86-18046518538 | yunbiochem@126.com | China | 321 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 20725 | 58 |
View Lastest Price from 1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-08 | 1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose
18968-05-3
|
1KG | 98%min HPLC | 100KGS | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-03-20 | 1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose
18968-05-3
|
$10.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2024-04-29 | 1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose
18968-05-3
|
$50.00 | 1kg | 99.10% | 50000kg | Ouhuang Engineering Materials (Hubei) Co., Ltd |
-
- 1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose
18968-05-3
- $0.00
- 98%min HPLC
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose
18968-05-3
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose
18968-05-3
- $50.00
- 99.10%
- Ouhuang Engineering Materials (Hubei) Co., Ltd
