ChemicalBook >> CAS DataBase List >>TRIETHYL 4-PHOSPHONOCROTONATE
TRIETHYL 4-PHOSPHONOCROTONATE
- CAS No.
- 10236-14-3
- Chemical Name:
- TRIETHYL 4-PHOSPHONOCROTONATE
- Synonyms
- Ethyl 4-(diethoxyphosphoryl);TRIETHYL 4-PHOSPHONOCROTONATE;TRIETHYL 4-PHOSPHONO-2-BUTENOATE;triethyl trans-4-phosphono-2-butenoate;4-PHOSPHONOCROTONIC ACID TRIETHYL ESTER;Ethyl 4-(diethoxyphosphinyl)-2-butenoate;TRANS-ETHYL-4-(DIETHYLPHOSPHONO)CROTONATE;triethyl 4-phosphonocrotonate, cis + trans;(E)-Ethyl 4-(diethoxyphosphoryl)but-2-enoate;Ethyl (E)-4-(diethoxyphosphoryl)but-2-enoate
- CBNumber:
- CB1664375
- Molecular Formula:
- C10H19O5P
- Molecular Weight:
- 250.23
- MDL Number:
- MFCD00009192
- MOL File:
- 10236-14-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-27 23:43:42
| Product description | Number | Pack Size | Price |
| Triethyl 4-phosphonocrotonate, mixture of isomers technical grade, 90% | 116092 | 10g | $120 |
| Ethyl 4-(diethoxyphosphoryl)crotonate 92% | OR42028 | 1g | $89 |
| Triethyl 4-phosphonocrotonate, mixture of isomers ≥89%(GC) | 36331 | 10G | $126 |
| Triethyl 4-phosphonocrotonate 95%+ | CM342294 | 5g | $120 |
| Ethyl 4-(Diethoxyphosphoryl)But-2-Enoate 94% | AA00076L | 1g | $52 |
| Boiling point | 135 °C0.4 mm Hg(lit.) |
|---|---|
| Density | 1.128 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Storage temp. 2-8°C |
| form | Liquid |
| color | Clear light yellow |
| InChI | 1S/C10H19O5P/c1-4-13-10(11)8-7-9-16(12,14-5-2)15-6-3/h7-8H,4-6,9H2,1-3H3/b8-7+ |
| InChIKey | LXLODBXSCRTXFG-BQYQJAHWSA-N |
| SMILES | CCOC(=O)\C=C\CP(=O)(OCC)OCC |
| CAS DataBase Reference | 10236-14-3(CAS DataBase Reference) |
| UNSPSC Code | 12352108 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29319090 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
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| NFPA 704 |
|
TRIETHYL 4-PHOSPHONOCROTONATE price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 116092 | Triethyl 4-phosphonocrotonate, mixture of isomers technical grade, 90% | 10236-14-3 | 10g | $120 | 2026-04-30 | Buy |
| Apolloscientific | OR42028 | Ethyl 4-(diethoxyphosphoryl)crotonate 92% | 10236-14-3 | 1g | $89 | 2026-06-04 | Buy |
| Chem-Impex | 36331 | Triethyl 4-phosphonocrotonate, mixture of isomers ≥89%(GC) | 10236-14-3 | 10G | $126 | 2026-05-19 | Buy |
| Chemenu | CM342294 | Triethyl 4-phosphonocrotonate 95%+ | 10236-14-3 | 5g | $120 | 2026-05-26 | Buy |
| aablocks | AA00076L | Ethyl 4-(Diethoxyphosphoryl)But-2-Enoate 94% | 10236-14-3 | 1g | $52 | 2026-05-25 | Buy |
TRIETHYL 4-PHOSPHONOCROTONATE Chemical Properties,Uses,Production
Chemical Properties
CLEAR LIGHT YELLOW LIQUID
Uses
Reactant for:
- Iminodipropionic acid as a leaving group for DNA polymerization by HIV-1 reverse transcriptase
- Stereoselective preparation of C1-C19 fragment of macrolide antibiotic aplyronine A using diastereoselective Nozaki-Hiyama-Kishi coupling reactions
- Orally bioavailable GPR40 agonist synthesis
- Synthesis of fluoroketone inhibitors of group VIA calcium-independent phospholipase A2
- Preaparation of mGlu4R agonists
- Dearomatizing cyclization of nicotinyl-substituted esters and ketones
Uses
Triethyl 4-phosphonocrotonate is used as a reactant for iminodipropionic acid as a leaving group for DNA polymerization by HIV-1 reverse transcriptase, orally bioavailable GPR40 agonist synthesis, preparation of mGlu4R agonists and synthesis of fluoroketone inhibitors of group VIA calcium-independent phospholipase A2.
reaction suitability
reaction type: C-C Bond Formation
TRIETHYL 4-PHOSPHONOCROTONATE Preparation Products And Raw materials
Raw materials
Preparation Products
TRIETHYL 4-PHOSPHONOCROTONATE Suppliers
Global( 70)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9996 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30225 | 58 |
| Alfa Chemistry | +1-5166625404; | Info@alfa-chemistry.com | United States | 20405 | 58 |
| XIAMEN AMITY INDUSTRY AND TRADE CO., LTD. | +8618950047208 | ellena@amitychem.com | China | 43414 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53803 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32343 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532; 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40228 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30123 | 84 |
View Lastest Price from TRIETHYL 4-PHOSPHONOCROTONATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-25 | TRIETHYL 4-PHOSPHONOCROTONATE
10236-14-3
|
$1.10 | 1g | 99.0% min | 100 tons min | Shaanxi Dideu Medichem Co. Ltd |
-
- TRIETHYL 4-PHOSPHONOCROTONATE
10236-14-3
- $1.10
- 99.0% min
- Shaanxi Dideu Medichem Co. Ltd
10236-14-3(TRIETHYL 4-PHOSPHONOCROTONATE)Related Search:
TRIETHYL 4-PHOSPHONOBUTYRATE
TRIETHYL 3-PHOSPHONOPROPIONATE
Dimethyl methylphosphonate
DIMETHYL ETHYLPHOSPHONATE
DIETHYL ALLYLPHOSPHONATE
Methyldiethoxyphosphine
DIMETHYL ALLYLPHOSPHONATE
ETHYL METHYLPHOSPHONIC ACID
METHYLPHOSPHONIC ACID
ETHYLPHOSPHONIC ACID
1of4
4-PHOSPHONOCROTONIC ACID TRIETHYL ESTER
TRANS-ETHYL-4-(DIETHYLPHOSPHONO)CROTONATE
TRIETHYL 4-PHOSPHONO-2-BUTENOATE
TRIETHYL 4-PHOSPHONOCROTONATE
TRIETHYL 4-PHOSPHONOCROTONATE, TECH., 90 %, MIXTURE OF ISOMERS
Triethyl 4-phosphonocrotonate, predominantly trans, 92%
triethyl 4-phosphonocrotonate, cis + trans
triethyl 4-phosphonocrotonate, mixture of isomers
triethyl trans-4-phosphono-2-butenoate
Triethyl 4-phosphonocrotonate, cis + trans, tech. 90%
Triethyl 4-phosphonocrotonate, 92%, predominantly trans
(E)-Ethyl 4-(diethoxyphosphoryl)but-2-enoate
Ethyl 4-(diethoxyphosphoryl)but-2-enoate, Ethyl 4-(diethylphosphono)crotonate
Triethyl 4-phosphonocrotonate, predoMinantly trans, 92% 50GR
Triethyl 4-phosphonocrotonate, mixture of isomers technical grade, 90%
Triethyl 4-phosphonocrotonate, cis and trans, technical, 90%
Ethyl 4-(diethoxyphosphoryl)
2-Butenoic acid, 4-(diethoxyphosphinyl)-, ethyl ester
Ethyl (E)-4-(diethoxyphosphoryl)but-2-enoate
Ethyl 4-(diethoxyphosphinyl)-2-butenoate
10236-14-3
C2H5O2POCH2CHCHCO2C2H5
C10H19O5P
C-C Bond Formation
Horner-Wadsworth-Emmons Reagents
Olefination
Synthetic Reagents
C-C Bond Formation
Horner-Wadsworth-Emmons Reagents
Olefination
