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ChemicalBook >> CAS DataBase List >>Cyclopentane-1,2-dicarboximude

Cyclopentane-1,2-dicarboximude

CAS No.
5763-44-0
Chemical Name:
Cyclopentane-1,2-dicarboximude
Synonyms
tetrahydrocyclopenta[c]pyrrole-1,3(2H,3aH)-dione;1,2-Cyclopentane Dicarboximide;CYCLOPENTANE-1,2-DICARBOXIMIDE;Gliclazide Impurity 18;Sodium 2-ethyl-3-oxobutanoate;Cyclopentane-1,2-dicarboximude;CycIopentane-1,2-dicarboximude;1,2-Cyclopentane Ddicarboximude;CYCLOPENTANE O-DICARBOXYLICIMIDE;SODIUM ACETATE TRIHYDRATE BP ACS USP
CBNumber:
CB1749070
Molecular Formula:
C7H9NO2
Molecular Weight:
139.15
MDL Number:
MFCD06411094
MOL File:
5763-44-0.mol
MSDS File:
SDS
Last updated:2026-05-27 23:46:08
Product description Number Pack Size Price
1,2-Cyclopentanedicarboximide TRC-C992045-5G 5g $109
1,2-Cyclopentanedicarboximide TRC-C992045-25G 25g $202
1,2-Cyclopentanedicarboximide TRC-C992045-1G 1g $63
Tetrahydrocyclopenta[c]pyrrole-1,3(2H,3aH)-dione 97% T39419 5g $12
Tetrahydrocyclopenta[c]pyrrole-1,3(2H,3aH)-dione 97% T39419 10g $18
More product size

Cyclopentane-1,2-dicarboximude Properties

Melting point 168 °C (dec.)
Boiling point 322.2±11.0 °C(Predicted)
Density 1.242±0.06 g/cm3(Predicted)
vapor pressure 0.017-0.031Pa at 20-25℃
storage temp. Sealed in dry,Room Temperature
solubility Acetonitrile (Slightly), Chloroform (Slightly)
pka 11.97±0.20(Predicted)
form Solid
color White to Off-White
InChI InChI=1S/C7H9NO2/c9-6-4-2-1-3-5(4)7(10)8-6/h4-5H,1-3H2,(H,8,9,10)
InChIKey QCWDCTDYSDJKTP-UHFFFAOYSA-N
SMILES N1C(=O)C2CCCC2C1=O
Surface tension 71.9mN/m at 1g/L and 20℃

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
REACH Registrations Active

Cyclopentane-1,2-dicarboximude price More Price(48)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC TRC-C992045-5G 1,2-Cyclopentanedicarboximide 5763-44-0 5g $109 2026-06-03 Buy
TRC TRC-C992045-25G 1,2-Cyclopentanedicarboximide 5763-44-0 25g $202 2026-06-03 Buy
TRC TRC-C992045-1G 1,2-Cyclopentanedicarboximide 5763-44-0 1g $63 2026-06-03 Buy
Synthonix T39419 Tetrahydrocyclopenta[c]pyrrole-1,3(2H,3aH)-dione 97% 5763-44-0 5g $12 2026-05-06 Buy
Synthonix T39419 Tetrahydrocyclopenta[c]pyrrole-1,3(2H,3aH)-dione 97% 5763-44-0 10g $18 2026-05-06 Buy
Product number Packaging Price Buy
TRC-C992045-5G 5g $109 Buy
TRC-C992045-25G 25g $202 Buy
TRC-C992045-1G 1g $63 Buy
T39419 5g $12 Buy
T39419 10g $18 Buy

Cyclopentane-1,2-dicarboximude Chemical Properties,Uses,Production

Description

1,2-cyclopentanediformylandne is the important intermediate of preparation gliclazide (Gliclazide).Gliclazide is s-generation sulfonylurea oral antidiabetic drug, be used for the treatment of non insulin dependent diabetes (type ii diabetes).

Uses

1,2-Cyclopentanedicarboximide was used as a reactant for [(benzopyranyl)amino]alkyl]azabicyclooctanedione anxiolytic,

Synthesis

1,2-Cyclopentanedicarboxylic acid

50483-99-3

formamide

77287-34-4

Cyclopentane-1,2-dicarboximude

5763-44-0

The general procedure for the synthesis of 1,2-cyclopentanedicarboxylic acid and formamide (CAS: 77287-34-4) as raw materials for the synthesis of 1,2-cyclopentanedicarboxylic acid is as follows: 50 g of 1,2-cyclopentanedicarboxylic acid and 15 g of formamide were mixed, and the reaction was carried out by raising the temperature up to 170 °C under the protection of nitrogen while evaporating the low-boiling by-products. The reaction progress was monitored by HPLC and terminated when the residual amount of raw material was less than 0.2%. After the reaction solution was cooled to 80 °C, 50 g of deionized water and 0.5 g of activated carbon were added and stirred at 50 °C for 30 min. The reaction mixture was thermally filtered and the filtrate was cooled to 20 °C and extracted with dichloromethane. The organic phase was concentrated to no fraction and dried at 90 °C. Subsequently 100 g of toluene was added, the mixture was cooled to 5 °C and dried under reduced pressure at 40 °C to give about 60.6 g of white crystal product. The yield of this step was 93.5% and the product was ≥99% pure and ≥98% content.

Toxicity evaluation

Cyclopentane-1,2-dicarboximude has specific target organ toxicity, it causes skin irritation and serious eye irritation.

References

[1] Patent: CN106866495, 2017, A. Location in patent: Paragraph 0016; 0017; 0018; 0019; 0020

90474-13-8
5763-44-0
Synthesis of Cyclopentane-1,2-dicarboximude from diethyl 1,2-cyclopentanedicarboxylate

Cyclopentane-1,2-dicarboximude Preparation Products And Raw materials

Global( 196)Suppliers
Supplier Tel Email Country ProdList Advantage
Jinan Qinmu Fine Chemical Co.,Ltd.
+8618660799346 sales@qinmuchem.com China 1008 58
Hangzhou ICH Biofarm Co., Ltd
+86-0571-28186870; +undefined8613073685410 sales@ichemie.com China 1006 58
Hebei Chuanghai Biotechnology Co., Ltd
+8615350571055 Sibel@chuanghaibio.com China 8738 58
Hebei Yanxi Chemical Co., Ltd.
+8618531123677 faithe@yan-xi.com China 5853 58
RongNa Biotechnology Co.,Ltd
+86-86-13583358881 +8618560316533 Brad@rongnabiotech.com China 3364 58
Hebei Chuanghai Biotechnology Co., Ltd
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Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21587 55
career henan chemical co
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NINGBO INNO PHARMCHEM CO., LTD.
13867897135 sales@nbinno.com CHINA 923 58

View Lastest Price from Cyclopentane-1,2-dicarboximude manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Cyclopentane-1,2-dicarboximude pictures 2026-06-09 Cyclopentane-1,2-dicarboximude
5763-44-0
$10.00 1ASSAYS 99% 1 ton RongNa Biotechnology Co.,Ltd
Cyclopentane-1,2-dicarboximude pictures 2026-03-30 Cyclopentane-1,2-dicarboximude
5763-44-0
1KG 98% 2000 Shenzhen Nexcon Pharmatechs Ltd.
Cyclopentane-1,2-dicarboximude pictures 2026-03-20 Cyclopentane-1,2-dicarboximude
5763-44-0
$1.00 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd

Cyclopentane-1,2-dicarboximude Spectrum

5763-44-0(Cyclopentane-1,2-dicarboximude)Related Search:

CYCLOPENTANE O-DICARBOXYLICIMIDE SODIUM ACETATE TRIHYDRATE BP ACS USP 4,5,6,6a-Tetrahydrocyclopenta[c]pyrrole-1,3(2H,3aH)-dione 4,5,6,6a-tetrahydro-3aH-cyclopenta[c]pyrrole-1,3-dione 4,5,6,6a-tetrahydro-3aH-cyclopenta[c]pyrrole-1,3-quinone Cyclopenta[c]pyrrole-1,3(2H,3aH)-dione, tetrahydro- Cyclopentane-1,2-dicarboximude 1,2-Cyclopentane Ddicarboximude Gliclazide Impurity 18 N-methylcarbamic acid (2-acetylphenyl) ester Tetrahydrocyclopenta[c]pyrrole-1,3(2H,3aH) 1,2-cycloglutarimide / glipizide intermediate Sodium 2-ethyl-3-oxobutanoate 1,2-Cyclopentanedicarboxylimide/1,2-Cyclopentanedicarboxylimide CycIopentane-1,2-dicarboximude tetrahydrocyclopenta[clpyrrole-1, 3(2H, 3aH) -dione 1,2-Cyclopentane Dicarboximide tetrahydrocyclopenta[c]pyrrole-1,3(2H,3aH)-dione CYCLOPENTANE-1,2-DICARBOXIMIDE 5763-44-0 Pharmaceutical Intermediates J's john's
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