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2-FLUORO-6-METHOXYPHENOL

2-FLUORO-6-METHOXYPHENOL structure

CAS No.: 73943-41-6

Chemical Name:: 2-FLUORO-6-METHOXYPHENOL

Synonyms: 2-FLUORO-6-METHOXYPHENOL;2-Methoxy-6-fluorophenol;2-Hydroxy-3-fluoroanisole;Phenol, 2-fluoro-6-methoxy-;2-Fluoro-6-methoxyphenol98%;2-Fluoro-6-methoxyphenol 98%

CBNumber:: CB2118840

Molecular Formula:: C7H7FO2

Molecular Weight:: 142.13

MDL Number:: MFCD00075140

MOL File:: 73943-41-6.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-27 23:54:43

Product description	Number	Pack Size	Price
2-Fluoro-6-methoxyphenol 98%	PC3817J	5g	$97
2-Fluoro-6-methoxyphenol 98%	PC3817J	25g	$345
2-Fluoro-6-methoxyphenol 98%	PC3817J	100g	$1293
2-Fluoro-6-methoxyphenol 98%	PC3817J	5g	$97
2-Fluoro-6-methoxyphenol 98%	PC3817J	25g	$345
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2-FLUORO-6-METHOXYPHENOL Properties

Boiling point	130-131 °C36 mm Hg(lit.)
Density	1.23 g/mL at 25 °C(lit.)
refractive index	n20/D 1.52(lit.)
Flash point	218 °F
storage temp.	Inert atmosphere,Room Temperature
pka	8.71±0.10(Predicted)
form	Liquid
color	Clear colorless to light brown
Specific Gravity	1.230
InChI	InChI=1S/C7H7FO2/c1-10-6-4-2-3-5(8)7(6)9/h2-4,9H,1H3
InChIKey	YZNHPLVFLRSVHY-UHFFFAOYSA-N
SMILES	C1(O)=C(OC)C=CC=C1F
CAS DataBase Reference	73943-41-6(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS07

Signal word

Warning

Hazard statements

H302-H318-H315-H319-H335

Precautionary statements

P261-P305+P351+P338-P280-P337+P313

Hazard Codes

Xi,C

Risk Statements

36/37/38

Safety Statements

26-37/39

WGK Germany

HazardClass

IRRITANT

HS Code

29095000

NFPA 704

	1
2		0

2-FLUORO-6-METHOXYPHENOL price More Price(58)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Apolloscientific	PC3817J	2-Fluoro-6-methoxyphenol 98%	73943-41-6	5g	$97	2026-06-04	Buy
Apolloscientific	PC3817J	2-Fluoro-6-methoxyphenol 98%	73943-41-6	25g	$345	2026-06-04	Buy
Apolloscientific	PC3817J	2-Fluoro-6-methoxyphenol 98%	73943-41-6	100g	$1293	2026-06-04	Buy
Apolloscientific	PC3817J	2-Fluoro-6-methoxyphenol 98%	73943-41-6	5g	$97	2026-06-04	Buy
Apolloscientific	PC3817J	2-Fluoro-6-methoxyphenol 98%	73943-41-6	25g	$345	2026-06-04	Buy

Product number	Packaging	Price	Buy
PC3817J	5g	$97	Buy
PC3817J	25g	$345	Buy
PC3817J	100g	$1293	Buy
PC3817J	5g	$97	Buy
PC3817J	25g	$345	Buy

2-FLUORO-6-METHOXYPHENOL Chemical Properties,Uses,Production

Chemical Properties

Clear colorless to light brown liquid

Synthesis

456-49-5

73943-41-6

The general procedure for the synthesis of 2-fluoro-6-methoxyphenol from m-fluoroanisole was as follows: 4.0 mL (9.4 mmol) of 2.36 M n-butyllithium solution was slowly added dropwise over a period of 1 h to 10.0 mL of anhydrous tetrahydrofuran (THF) solution containing 1.28 g (10 mmol) of m-fluoroanisole (1) according to the method of Ladd and Weinstock The reaction temperature was maintained below -65 °C and cooled using a dry ice/acetone bath. The reaction mixture was stirred at -78 °C and under nitrogen protection for 2 hours. Subsequently, 1.17 g (11 mmol) of trimethoxyborane dissolved in 2.00 mL of anhydrous THF was added dropwise over 1 h at -78 °C and stirring was continued at -78 °C for 30 min. The reaction mixture was slowly warmed to 0 °C and 0.88 mL (15 mmol) of glacial acetic acid was added, followed by the dropwise addition of 1 mL (10 mmol) of 30% hydrogen peroxide (H2O2) solution. The reaction mixture was stirred at 25 °C overnight. After completion of the reaction, the reaction solution was diluted with 10 mL of water and extracted with THF (2 × 10 mL). The organic phases were combined and washed sequentially with H2O (2 × 7 mL) and 10% brine (2 × 3 mL). The organic phase was dried with anhydrous magnesium sulfate (MgSO4) and concentrated under reduced pressure to give 1.16 g (80% yield) of 2-fluoro-6-methoxyphenol. The yields of successive replicate experiments were as follows: 15.5 g of product (63% yield) was obtained from 174 mmol of feedstock; 29.7 g of product (80% yield) was obtained from 261 mmol of feedstock. The structures of the products were analyzed by 1H NMR (300 MHz, CDCl3) δ 6.82-6.63 (m, 1H), 5.51 (s, 1H), 3.90 (s, 1H); 19F NMR (282 MHz, CDCl3) δ -137.61 ppm (m, 1F); EI-MS: m/z 142 (M+), 127.

References

[1] Synlett, 2014, vol. 25, # 20, p. 2891 - 2894
[2] Patent: WO2017/176812, 2017, A1. Location in patent: Paragraph 0405
[3] Journal of Medicinal Chemistry, 1990, vol. 33, # 8, p. 2204 - 2211
[4] Journal of Organic Chemistry, 1981, vol. 46, # 1, p. 203 - 206
[5] Journal of Chemical Research, Miniprint, 1986, # 1, p. 171 - 193

2-FLUORO-6-METHOXYPHENOL synthesis

Synthesis of 2-FLUORO-6-METHOXYPHENOL from 3-Fluoroanisole

2-FLUORO-6-METHOXYPHENOL Preparation Products And Raw materials

Raw materials

[1,1'-Biphenyl]-2-ol, 2'-fluoro-3,6'-dimethoxy- Benzene, 1-fluoro-3-methoxy-2-(phenylmethoxy)- 3-Fluoro-2-methoxyphenol 2-(Benzyloxy)-3-fluorophenol 1-FLUORO-2,3-DIMETHOXYBENZENE

2-Bromo-3-fluoroanisole 2-Bromo-3-fluorophenol 3-Fluoroanisole Tetrahydrofuran n-Butyllithium

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Preparation Products

2-FLUORO-6-METHOXYPHENOL Suppliers

Global( 115)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29792	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10000	58
Win-Win chemical CO., Limited	+86-0086-577-64498589 +86-15355981851	sales@win-winchemical.com	China	14304	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52704	58
Changzhou Anxuan Chemical Co., Ltd	+86-0519-89882563 +86-18961279162	andy@anxuanchem.com	China	4327	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Fuxin Pharmaceutical	58
Win-Win chemical CO., Limited	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Changzhou Anxuan Chemical Co., Ltd	58

View Lastest Price from 2-FLUORO-6-METHOXYPHENOL manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-12-20	2-FLUORO-6-METHOXYPHENOL 73943-41-6	$1.00	1KG	99%	1000KG	Career Henan Chemical Co

2-FLUORO-6-METHOXYPHENOL
73943-41-6
$1.00
99%
Career Henan Chemical Co

2-FLUORO-6-METHOXYPHENOL Spectrum

2-FLUORO-6-METHOXYPHENOL(73943-41-6)¹HNMR 2-FLUORO-6-METHOXYPHENOL(73943-41-6)IR 2-FLUORO-6-METHOXYPHENOL(73943-41-6)Raman 2-FLUORO-6-METHOXYPHENOL(73943-41-6)FT-IR

73943-41-6(2-FLUORO-6-METHOXYPHENOL)Related Search:

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2-FLUORO-6-METHOXYPHENOL 2-Fluoro-6-methoxyphenol 98% 2-Fluoro-6-methoxyphenol98% 2-Hydroxy-3-fluoroanisole 2-Methoxy-6-fluorophenol Phenol, 2-fluoro-6-methoxy- 73943-41-6 FC6H3OCH3OH Oxygen Compounds Phenols Organic Building Blocks Building Blocks Oxygen Compounds Phenols Phenol&Thiophenol&Mercaptan Organic Building Blocks

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