Benzyl chloromethyl ether
- CAS No.
- 3587-60-8
- Chemical Name:
- Benzyl chloromethyl ether
- Synonyms
- BOM-Cl;BENZYL CHLOROMETHYL ETHER;BENZYLOXYMETHYL CHLORIDE;Chloromethyl benzyl ether;oromethyL;Benzylchloromethy;Benzylchloromethyl e;α-Chloromethoxytoluene;Benzlchloromethyl ether;Benzyylchloromethyl ether
- CBNumber:
- CB2130648
- Molecular Formula:
- C8H9ClO
- Molecular Weight:
- 156.61
- MDL Number:
- MFCD00000886
- MOL File:
- 3587-60-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Benzyl chloromethyl ether technical, ~60% (NMR) | 13282 | 10ml | $59 |
| Benzyl chloromethyl ether technical, ~60% (NMR) | 13282 | 50ml | $171 |
| Benzyl Chloromethyl Ether >90.0%(GC) | B1207 | 25g | $50 |
| Benzyl Chloromethyl Ether >90.0%(GC) | B1207 | 100g | $146 |
| Benzyl chloromethyl ether Asreported | 264013 | 25g | $297 |
| More product size | |||
| Boiling point | 102 °C/14 mmHg (lit.) |
|---|---|
| Density | 1.126 g/mL at 20 °C (lit.) |
| refractive index |
n |
| Flash point | 91 °C |
| storage temp. | 2-8°C |
| solubility | Chloroform (Sparingly), Ethyl Acetate (Slightly) |
| form | Liquid |
| color | Clear colorless to pale yellow |
| Water Solubility | Soluble in water [2.7 g/L (25 C)] |
| BRN | 1364034 |
| Stability | Moisture Sensitive, Toxic |
| InChI | InChI=1S/C8H9ClO/c9-7-10-6-8-4-2-1-3-5-8/h1-5H,6-7H2 |
| InChIKey | LADPCMZCENPFGV-UHFFFAOYSA-N |
| SMILES | C1(COCCl)=CC=CC=C1 |
| CAS DataBase Reference | 3587-60-8(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzyl chloromethyl ether(3587-60-8) |
| UNSPSC Code | 12352101 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |     GHS05,GHS07,GHS08,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302+H332-H315-H317-H318-H334-H335-H350-H373-H410 | |||||||||
| Precautionary statements | P273-P280-P301+P312-P302+P352-P305+P351+P338-P308+P313 | |||||||||
| target organs | Heart,forestomach, Respiratory system | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | T,Xn,N | |||||||||
| Risk Statements | 45-22-23-37/38-41-48/22-36/37/38-20/21/22-50-43 | |||||||||
| Safety Statements | 53-26-39-45-36/37/39-36-61 | |||||||||
| RIDADR | UN 2810 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 19-21 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29093090 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 4 Inhalation Acute Tox. 4 Oral Aquatic Acute 1 Aquatic Chronic 1 Carc. 1B Eye Dam. 1 Resp. Sens. 1 Skin Irrit. 2 Skin Sens. 1 STOT RE 2 Oral STOT SE 3 |
|||||||||
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
Benzyl chloromethyl ether price More Price(85)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 13282 | Benzyl chloromethyl ether technical, ~60% (NMR) | 3587-60-8 | 10ml | $59 | 2026-04-30 | Buy |
| Sigma-Aldrich | 13282 | Benzyl chloromethyl ether technical, ~60% (NMR) | 3587-60-8 | 50ml | $171 | 2026-04-30 | Buy |
| TCI Chemical | B1207 | Benzyl Chloromethyl Ether >90.0%(GC) | 3587-60-8 | 25g | $50 | 2026-04-30 | Buy |
| TCI Chemical | B1207 | Benzyl Chloromethyl Ether >90.0%(GC) | 3587-60-8 | 100g | $146 | 2026-04-30 | Buy |
| Usbiological | 264013 | Benzyl chloromethyl ether Asreported | 3587-60-8 | 25g | $297 | 2026-06-03 | Buy |
Benzyl chloromethyl ether Chemical Properties,Uses,Production
Description
Benzyl chloromethyl ether is a powerful alkylating agent and a potential carcinogen. It is also a mild lachrymator, reacting with water and alcohols to form hydrogen chloride. The process should be performed in a hood and inhalation and skin contact should be avoided.
Chemical Properties
Colorless liquid
Uses
Benzyl chloromethyl ether is employed in the introduction of benzoyloxy- and hydroxymethyl groups.
Application
Benzyl chloromethyl ether is mainly used in organic chemistry as a reagent for the synthesis of various compounds and as a solvent for organic reactions. It is also used as a catalyst for the synthesis of many compounds such as pesticides, dyes and surfactants. In addition, it contributes to the manufacture of polymers such as polystyrene and polyurethane, and polymers for drug delivery systems and tissue engineering scaffolds in the pharmaceutical field.
Preparation
Benzyl chloromethyl ether is prepared from benzyl alcohol, aqueous formaldehyde and hydrogen chloride. The specific synthesis steps are as follows:
A 1-l, three-necked flask equipped with an overhead mechanical stirrer with a Teflon paddle, gas-inlet tube, thermometer, and a calcium chloride drying tube is charged with 216 g. (2.00 moles) of benzyl alcohol and 66 g. (2.20 moles as CH2O) of paraformaldehyde. The resulting mixture is maintained at 20–25° with a water bath during addition of anhydrous hydrogen chloride at a moderate rate, with stirring. After approximately 2 hours the reaction is complete, as judged by the appearance of two clear homogeneous phases. The layers are separated, and the upper layer is diluted with 800 ml. of pentane and dried over anhydrous magnesium sulfate for 3 hours at 0°, with stirring. The drying agent is removed by filtration, 2–3 g. of anhydrous calcium chloride is added to the filtrate, and the solution is concentrated on a rotary evaporator. The residual liquid, which is nearly pure benzyl chloromethyl ether, is decanted, affording 260 g. (83%) of crude product. This crude benzyl chloromethyl ether, which is suitable for use in some applications, is stored over anhydrous calcium chloride at 0° under an inert atmosphere.
If further purification is desired, just prior to use the crude material (40 g.) may be distilled at approximately 3 mm from anhydrous calcium chloride, affording very pure benzyl chloromethyl ether (35 g.), b.p. 70–71° (3 mm).
Synthesis Reference(s)
Synthesis, p. 762, 1983 DOI: 10.1055/s-1983-30506
Benzyl chloromethyl ether Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| .GZ HONESTCHEM CO.,LTD | +86-15013270415 | honestchemical@foxmail.com | China | 300 | 58 |
| ROSEWA HOLDING GROUP CO.,LIMITED | +86-023-62871537 | sales@rosewachem.com | China | 2812 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-173 9270 1263 | 1057@dideu.com | China | 3957 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +86-17531190177 | faithe@yan-xi.com | China | 5853 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 | sales1@chuanghaibio.com | China | 5220 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +86-17732866630 | mina@chuanghaibio.com | China | 18126 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14026 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | 18957127338 | stella@zetchem.com | China | 2994 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2950 | 58 |
Related articles
- Benzyl Chloromethyl Ether: Synthesis & Alkylation Applications
- Benzyl chloromethyl ether serves as a key intermediate for alkylation and hydroxyl protection; its simplified in situ synthesi....
- Jan 9，2026
View Lastest Price from Benzyl chloromethyl ether manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-31 | Benzylchloromethyl ether
3587-60-8
|
$1.00 | 300g | 99.8% | 20 TONS | .GZ HONESTCHEM CO.,LTD | |
 |
2026-05-28 | Benzylchloromethyl Ether
3587-60-8
|
$2.00-5.00 | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2025-06-27 | Benzylchloromethyl ether
3587-60-8
|
1KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd |
-
- Benzylchloromethyl ether
3587-60-8
- $1.00
- 99.8%
- .GZ HONESTCHEM CO.,LTD
-
- Benzylchloromethyl Ether
3587-60-8
- $2.00-5.00
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- Benzylchloromethyl ether
3587-60-8
- $0.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
3587-60-8(Benzyl chloromethyl ether)Related Search:
1of4
