ChemicalBook >> CAS DataBase List >>BENAZEPRILAT
BENAZEPRILAT
- CAS No.
- 86541-78-8
- Chemical Name:
- BENAZEPRILAT
- Synonyms
- Cibacen;CGS-14831;BENAZEPRILAT;L-Tyrosine-d;Benazepril EP Imp C;Benazepril Impurity C;Benazepril Impurity 3;BENAZEPRILAT HCL HYDRATE;Benazepril EP Impurity C;Benazeprilat (CGS 14831)
- CBNumber:
- CB2144780
- Molecular Formula:
- C22H24N2O5
- Molecular Weight:
- 396.44
- MDL Number:
- MFCD00864465
- MOL File:
- 86541-78-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-04-24 14:58:15
| Product description | Number | Pack Size | Price |
| Benazepril Related Compound C United States Pharmacopeia (USP) Reference Standard | 1048641 | 50mg | $1340 |
| Benazeprilat ≥98% | 21796 | 1mg | $75 |
| Benazeprilat ≥98% | 21796 | 5mg | $315 |
| Benazeprilat ≥98% | 21796 | 10mg | $589 |
| Benazeprilat ≥98% | 21796 | 1mg | $68 |
| More product size | |||
| Melting point | 270-272°C |
|---|---|
| alpha | D -200.5° (c = 1 in 3% aqueous NH4OH) |
| Boiling point | 711.3±60.0 °C(Predicted) |
| Density | 1.34±0.1 g/cm3(Predicted) |
| storage temp. | -20°C Freezer, Under Inert Atmosphere |
| solubility | Aqueous Base (Slightly), DMSO (Slightly) |
| form | Solid |
| pka | 2.17±0.10(Predicted) |
| color | White to Off-White |
| Major Application | pharmaceutical (small molecule) |
| InChI | 1S/C22H24N2O5/c25-20(26)14-24-19-9-5-4-8-16(19)11-13-17(21(24)27)23-18(22(28)29)12-10-15-6-2-1-3-7-15/h1-9,17-18,23H,10-14H2,(H,25,26)(H,28,29)/t17-,18-/m0/s1 |
| InChIKey | MADRIHWFJGRSBP-ROUUACIJSA-N |
| SMILES | N1(CC(O)=O)C2=CC=CC=C2CC[C@H](N[C@H](C(O)=O)CCC2=CC=CC=C2)C1=O |
| CAS DataBase Reference | 86541-78-8 |
| FDA UNII | JRM708L703 |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| WGK Germany | WGK 3 |
|---|---|
| HS Code | 2933790002 |
| Storage Class | 11 - Combustible Solids |
BENAZEPRILAT price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 1048641 | Benazepril Related Compound C United States Pharmacopeia (USP) Reference Standard | 86541-78-8 | 50mg | $1340 | 2026-04-30 | Buy |
| Cayman Chemical | 21796 | Benazeprilat ≥98% | 86541-78-8 | 1mg | $75 | 2026-04-30 | Buy |
| Cayman Chemical | 21796 | Benazeprilat ≥98% | 86541-78-8 | 5mg | $315 | 2026-04-30 | Buy |
| Cayman Chemical | 21796 | Benazeprilat ≥98% | 86541-78-8 | 10mg | $589 | 2026-04-30 | Buy |
| Cayman Chemical | 21796 | Benazeprilat ≥98% | 86541-78-8 | 1mg | $68 | 2024-03-01 | Buy |
BENAZEPRILAT Chemical Properties,Uses,Production
Chemical Properties
Crystalline Solid
Uses
Benazeprilat is a metabolite of Benazepril, which is used as an antihypertensive.
Definition
ChEBI: A benzazepine that is 1,3,4,5-tetrahydro-2H-1-benzazepin-2-one in which the hydrogen attached to the nitrogen is replaced by a carboxy methyl group and in which the 3-pro-S hydrogen is replaced by the amino roup of (2S)-2-amino-4-phenylbutanoic acid. An angiotensin-converting enzyme inhibitor, it is used as its monoester prodrug benazepril in the treatment of hypertension and heart failure.
in vivo
Benazeprilat (10 mg/kg, intravenous injection) and amlodipine (0.5 mg/kg, intravenous injection) in combination produce great hypotensive effect[2].
Benazepril (0.7 mg/kg, oral) markedly influences the dynamics of systemic RAAS peptides, resulting in a substantial decrease in AII and ALD while increasing PRA and AI[3].
| Animal Model: | Male SHR (14-16 weeks of age, 250-350 g)[2]. |
| Dosage: | 10 mg/kg |
| Administration: | I.V; once a day for 2 days. |
| Result: | Produced hypotensive effect. |
| Animal Model: | Beagle dogs (12.0-19.5 kg)[3]. |
| Dosage: | 0.7 mg/kg |
| Administration: | P.O, once a day for 5 days. |
| Result: | Effected systemic RAAS peptides. |
BENAZEPRILAT Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 130)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19853 | 58 |
| CR Corporation Limited | +8613062833949 | fred.wen@crcorporation.cn | China | 8645 | 58 |
| sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12373 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43333 | 58 |
| ShenZhen H&D Pharmaceutical Technology Co., LTD | +8618627948422 | sale@hdimpurity.com | China | 3681 | 58 |
View Lastest Price from BENAZEPRILAT manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-12 | Benazepril EP Impurity C
86541-78-8
|
10mg | 0.98 | 10g | ShenZhen H&D Pharmaceutical Technology Co., LTD |
-
- Benazepril EP Impurity C
86541-78-8
- $0.00
- 0.98
- ShenZhen H&D Pharmaceutical Technology Co., LTD
86541-78-8(BENAZEPRILAT)Related Search:
CGP 14829A
(S)-3-AMino-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic Acid
BENAZEPRIL-D5 HYDROCHLORIDE
Benazepril-(17a)
Benazepril-(S,R)
BENAZEPRILAT-D5
Benazepril Impurity 1 (Benazepril Methyl Ester)
S-ATBA
Benazepril hydrochloride
BENAZEPRILAT
1of4
BENAZEPRILAT
BENAZEPRILAT HCL HYDRATE
(3S)-3-[[(S)-1-Carboxy-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid
CGS-14831
Benazepril Related Compound C (50 mg) ((3S)-3-[[(1S)-1-
carboxy-3-phenylpropyl]amino-2,3,4,5-tetrahydro-2-oxo-
1H-1-benzazepine]-1-acetic acid)
(3S)-3-[[(1S)-1-carboxy-3-phenylpropyl]aMino-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine]-1-acetic acid
Benazepril Related CoMpound C
Cibacen
BENAZEPRILAT HYDROCHLORIDE HYDRATE
1H-1-Benzazepine-1-acetic acid, 3-(1S)-1-carboxy-3-phenylpropylamino-2,3,4,5-tetrahydro-2-oxo-, (3S)-
Benazepril hydrochloride impurity C
Benazepril Impurity 3(Benazepril EP Impurity C)
Benazepril Diacid (Benaz. EP Impurity C)
Benazepril Impurity C
Benazepril EP Imp C
Benazepril EP Impurity C
Benazepril EP Impurity C (Disodium Salt)
(S)-2-(((S)-1-(carboxymethyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl)amino)-4-phenylbutanoic acid
Benazepril EP Impurity C/ Benazepril Related Compund C (Benazeprilat)
Benazeprilat (CGS 14831)
BenazeprilatQ: What is
Benazeprilat Q: What is the CAS Number of
Benazeprilat Q: What is the storage condition of
Benazeprilat Q: What are the applications of
Benazeprilat
Benazepril Impurity 3
(2S)-2-[[(3S)-1-(Carboxymethyl)-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-3-yl]amino]-4-phenylbutanoic Acid
Benazepril Related Compound C ((3S)-3-[[(1S)-1-carboxy-3-phenylpropyl]amino-2,3,4,5-tetrahydro-2-ox (1048641)
Benazepril USP Related Compound C
L-Tyrosine-d
CGS14831|||CGS-14831|||CGS 14831
Benazepril EP Impurity C (Benazepril USP Related Compound C, Benazeprilat)
(2S)-2-[[(3S)-1-(Carboxymethyl)-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-3-yl]amino]-4-phenylbutanoi
Benazeprilat EP Impurity C
(2S)-2-[[(3S)-1-(Carboxymethyl)-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-3-yl]amino]-4-phenylbutanoic Acid (Benazeprilat)
Benazepril Imp. C (EP): (3S)-3-[[(1S)-1-Carboxy-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic Acid
(3S)-3-[[(S)-1-Carboxy-3-phenylpropyl]amino]-2
5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid
86541-78-8
Intermediates & Fine Chemicals
Metabolites
Pharmaceuticals
Aromatics
Heterocycles
Metabolites & Impurities
Chiral Reagents
