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ChemicalBook >> CAS DataBase List >>1-[2-AMino-1-(4-Methoxyphenyl)ethyl]cyclohexanol

1-[2-AMino-1-(4-Methoxyphenyl)ethyl]cyclohexanol

CAS No.
93413-77-5
Chemical Name:
1-[2-AMino-1-(4-Methoxyphenyl)ethyl]cyclohexanol
Synonyms
N,N-didesmethylvenlafaxine;1-(4-METHOXYPHENYL)-2-AMINOETHYL CYCLOHEXANOL HYDROCHLORIDE;Dinorvenlafaxin;Dinorvenlafaxine;Venlafaxine intermediate;Venlafaxine EP IMpurity C;Venlafaxine-N,N-didesmethyl; D,L-N,N-Didesmethylvenlafaxine;1-[2-AMINO-1-(4-METHOXYPHENYL)ETHYL]CYCLOHEXANOL;1-(4-Methoxyphenyl)-2-aminoethyl cyclohexanol hydr
CBNumber:
CB2154879
Molecular Formula:
C15H23NO2
Molecular Weight:
249.35
MDL Number:
MFCD07367622
MOL File:
93413-77-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 23:57:13
Product description Number Pack Size Price
Dinorvenlafaxine Axon1726 5mg $82.5
Dinorvenlafaxine Axon1726 25mg $247.5
1-(2-Amino-1-(4-methoxyphenyl)ethyl)cyclohexanol 100% AA00IKBU 5mg $144
1-(2-Amino-1-(4-methoxyphenyl)ethyl)cyclohexanol 100% AA00IKBU 25mg $350
1-[2-Amino-1-(4-methoxyphenyl)ethyl]cyclohexanol 95% AD259890 25MG $795
More product size

1-[2-AMino-1-(4-Methoxyphenyl)ethyl]cyclohexanol Properties

Melting point 102-105 °C
Boiling point 394.6±22.0 °C(Predicted)
Density 1.107±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility soluble in DCM, Methanol
pka 14.75±0.20(Predicted)
form Oil
color Brown
CAS DataBase Reference 93413-77-5(CAS DataBase Reference)
FDA UNII 3235EO37UJ

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

1-[2-AMino-1-(4-Methoxyphenyl)ethyl]cyclohexanol price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Axon Medchem Axon1726 Dinorvenlafaxine 5mg $82.5 2026-05-19 Buy
Axon Medchem Axon1726 Dinorvenlafaxine 25mg $247.5 2026-05-19 Buy
aablocks AA00IKBU 1-(2-Amino-1-(4-methoxyphenyl)ethyl)cyclohexanol 100% 93413-77-5 5mg $144 2026-05-29 Buy
aablocks AA00IKBU 1-(2-Amino-1-(4-methoxyphenyl)ethyl)cyclohexanol 100% 93413-77-5 25mg $350 2026-05-29 Buy
ACHEMBLOCK AD259890 1-[2-Amino-1-(4-methoxyphenyl)ethyl]cyclohexanol 95% 93413-77-5 25MG $795 2026-05-27 Buy
Product number Packaging Price Buy
Axon1726 5mg $82.5 Buy
Axon1726 25mg $247.5 Buy
AA00IKBU 5mg $144 Buy
AA00IKBU 25mg $350 Buy
AD259890 25MG $795 Buy

1-[2-AMino-1-(4-Methoxyphenyl)ethyl]cyclohexanol Chemical Properties,Uses,Production

Synthesis

To a mechanically stirred solution of AlCl3 (103.60 g, 0.779 mol) in THF (900 ml), at 0 oC, LiAlH4 (59.80 g, 1.575 mol) was added cautiously, in portions. Temperature was maintained below 10 oC. A solution of 2-(1-Hydroxycyclohexyl)-2-(4-methoxyphenyl) acetonitrile(130.0 g, 0.530 mol) in THF (500 ml) was added drop-wise over a period of 1.5 hours. The reaction mixture was then brought to room temperature and stirred for 30 minutes. The reaction mixture was again cooled in an ice-salt bath. The reaction was quenched with ethyl acetate (60 ml) maintaining the temperature below 10 oC. The reaction mixture was then transferred to a beaker, cooled externally in an ice-salt bath and treated very cautiously with 25% aq. NaOH solution (360 ml) with mechanical stirring. (After addition of about 50 ml 25% aq. NaOH solution, a hard solid was formed, cooling was removed and the contents were stirred manually during the addition of remaining NaOH solution). The solid was loosened at room temperature, which was further stirred for 1 hour. A bright white solid appeared. The solid was filtered off, washed thoroughly with ethyl acetate. The filtrate was concentrated in vacuo and combined with the above washings, washed with brine, dried over anhydrous Na2SO4, filtered and ethyl acetate removed under reduced pressure to obtain aminoalcohol 38 as a thick yellow oil (129.4 g).
Synthesis of 1-[2-AMino-1-(4-Methoxyphenyl)ethyl]cyclohexanol

Chemical Properties

Pale Yellow Oil

Uses

An intermediate in the synthesis of N,O-Didesmethylvenlafaxine, a metabolite of Venlafaxine

Definition

ChEBI: A monomethoxybenzene that is the N,N-didesmethyl derivative of venlafaxine.

1-[2-AMino-1-(4-Methoxyphenyl)ethyl]cyclohexanol Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 111)Suppliers
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ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD 		+86-13017695106 +86-13676922317 jiuyitime@fdachem.com China 16512 58
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29815 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49979 58
SIMAGCHEM CORP 		+86-5922680277 +86-13806087780 sale@simagchem.com China 17346 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 +8617705817739 info@dycnchem.com China 52705 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418684 +8618949823763 sales@tnjchem.com China 25356 58
HANGZHOU LEAP CHEM CO., LTD. 		+86-571-87711850 market18@leapchem.com China 24597 58
PT CHEM GROUP LIMITED 		+86-85511178; peter68@ptchemgroup.com China 35425 58
SUZHOU SENFEIDA CHEMICAL CO.,LTD 		+86-0512-83500002 +8618662433356 3899766280@qq.com China 26362 58
Changzhou AniKare Pharmatech Co., Ltd. 		+86-0519-8359-8696 +8618018249389 sales@anikare.com China 9969 58

View Lastest Price from 1-[2-AMino-1-(4-Methoxyphenyl)ethyl]cyclohexanol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-(4-Methoxyphenyl)-2-aminoethyl cyclohexanol hydrochloride pictures 2026-04-17 1-(4-Methoxyphenyl)-2-aminoethyl cyclohexanol hydrochloride
93413-77-5
 $2.20-8.80 1kg 99%min 100kg ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
1-(4-Methoxyphenyl)-2-aminoethyl cyclohexanol hydrochlorideS pictures 2019-08-30 1-(4-Methoxyphenyl)-2-aminoethyl cyclohexanol hydrochlorideS
93413-77-5
 $1.00 1KG 95%-99% 100KG Career Henan Chemical Co

1-[2-AMino-1-(4-Methoxyphenyl)ethyl]cyclohexanol Spectrum

1-[2-aMino-1-(4-Methoxyphenyl)ethyl]cyclohexan-1-ol Venlafaxine EP IMpurity C 2-(4-Methoxyphenyl)-2-(1-hydroxycyclohexyl)-ethylamine Venlafaxine intermediate D,L-N,N-Didesmethylvenlafaxine 1-[2-Amino-1-(4-methoxyphenyl)ethyl]cyclohexanol (see D441570) Dinorvenlafaxine Dinorvenlafaxin 1-(2-Amino-1-[(4methoxy-2-(phenylethyl)]-cyclohexanol 1-[2-AMINO-1-(4-METHOXYPHENYL)ETHYL]CYCLOHEXANOL HCL 2-(4-METHOXYPHENYL)-2-(1-HYDROXYCYCLOHEXYL)ETHYLAMINE HYDROCHLORIDE 1-[2-AMINO-1-(4-METHOXYPHENYL)ETHYL]CYCLOHEXANOL 1-[2-amino-1-(4-methoxyphenyl)ethyl]-1-cyclohexanol 1-(4-Methoxyphenyl)-2-aminoethyl cyclohexanol hydrochlorideS Venlafaxine EP Impurity C/1-[2-Amino-1-(4-methoxyphenyl)ethyl]cyclohexanol 1-[2-Amino-1-(4-methoxyphenyl)ethyl]cyclohexanol DISCONTINUED. Please see A611968 D,L-N,N-Didesmethyl Venlafaxine DISCONTINUED. Please see A611968 1-(4-Methoxyphenyl)-2-aminoethyl cyclohexanol hydr Venlafaxine-N,N-didesmethyl 1-(4-METHOXYPHENYL)-2-AMINOETHYL CYCLOHEXANOL HYDROCHLORIDE N,N-didesmethylvenlafaxine 93413-77-5 C15H23NO2HCI Velafaxine Various Metabolites and Impurities Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals
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