Vatalanib base
- CAS No.
- 212141-54-3
- Chemical Name:
- Vatalanib base
- Synonyms
- VATALANIB;VataL;PTK787 2HCl;Vatalanib HCl;VATALANIB BASE;Vatalanib 2HCL;PTK787 free base;PTK/ZK free base;Vatalanib (PTK787);anib (PTK787) 2HCL
- CBNumber:
- CB2173616
- Molecular Formula:
- C20H15ClN4
- Molecular Weight:
- 346.81
- MDL Number:
- MFCD08458963
- MOL File:
- 212141-54-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Vatalanib | MIA14154 | 100mg | $342 |
| Vatalanib | MIA14154 | 1g | $1073.8 |
| Vatalanib 99.93% | CS-5248 | 5mg | $54 |
| Vatalanib 99.93% | CS-5248 | 10mg | $87 |
| Vatalanib 99.93% | CS-5248 | 25mg | $157 |
| More product size | |||
| Melting point | 209-212° |
|---|---|
| Boiling point | 587.8±50.0 °C(Predicted) |
| Density | 1.330±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C(protect from light) |
| solubility | ≥16.85 mg/mL in DMSO; ≥3.0125 mg/mL in EtOH with gentle warming and ultrasonic; ≥32.53 mg/mL in H2O with gentle warming and ultrasonic |
| form | solid |
| pka | 5.46±0.10(Predicted) |
| color | Light yellow to yellow |
| EWG's Food Scores | 1 |
| NCI Dictionary of Cancer Terms | vatalanib |
| FDA UNII | 5DX9U76296 |
| NCI Drug Dictionary | vatalanib |
Vatalanib base price More Price(54)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | MIA14154 | Vatalanib | 212141-54-3 | 100mg | $342 | 2026-06-04 | Buy |
| Biosynth | MIA14154 | Vatalanib | 212141-54-3 | 1g | $1073.8 | 2026-06-04 | Buy |
| ChemScene | CS-5248 | Vatalanib 99.93% | 212141-54-3 | 5mg | $54 | 2026-06-04 | Buy |
| ChemScene | CS-5248 | Vatalanib 99.93% | 212141-54-3 | 10mg | $87 | 2026-06-04 | Buy |
| ChemScene | CS-5248 | Vatalanib 99.93% | 212141-54-3 | 25mg | $157 | 2026-06-04 | Buy |
Vatalanib base Chemical Properties,Uses,Production
Uses
anti-viral
Uses
Vatalanib (PTK787) is an inhibitor of VEGFR2/KDR, Flt-1 and c-Kit with IC50 of 37 nM, 77 nM and 730 nM, respectively.
Definition
ChEBI: A member of the class of phthalazines that is phthalazine in which the hydrogens at positions 1 and 4have been replaced by a p-chlorophenylamino group and a pyridin-4-ylmethyl group, respectively. It is a multi-targeted tyrosine kinase inhibit r for all isoforms of VEGFR, PDGFR and c-Kit.
in vivo
Vatalanib induces dose-dependent inhibition of the angiogenic response to VEGF and PDGF in both a growth factor implant model and a tumor cell-driven angiogenesis model after once-daily oral dosing (25-100 mg/kg). In the same dose range, Vatalanib also inhibits the growth and metastasesof several human carcinomas in nude mice without significant effect on circulating blood cells or bone marrow leukocytes[1].
IC 50
VEGFR2: 37 nM (IC50)
Vatalanib base Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| RongNa Biotechnology Co.,Ltd | +86-86-13583358881 +8618560316533 | Brad@rongnabiotech.com | China | 3364 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5742 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19853 | 58 |
View Lastest Price from Vatalanib base manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-08 | Vatalanib base
212141-54-3
|
$10.00 | 1ASSAYS | 99% | 1 ton | RongNa Biotechnology Co.,Ltd | |
 |
2026-04-22 | Vatalanib free base
212141-54-3
|
$40.00-118.00 | 99.52% | 10g | TargetMol Chemicals Inc. | ||
 |
2019-12-24 | Vatalanib base
212141-54-3
|
$1.00 | 100g | 98%min | Career Henan Chemical Co |
-
- Vatalanib base
212141-54-3
- $10.00
- 99%
- RongNa Biotechnology Co.,Ltd
-
- Vatalanib free base
212141-54-3
- $40.00-118.00
- 99.52%
- TargetMol Chemicals Inc.
-
- Vatalanib base
212141-54-3
- $1.00
- 98%min
- Career Henan Chemical Co
