ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
- CAS No.
- 19444-84-9
- Chemical Name:
- ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
- Synonyms
- 2-HYDROXY-GAMMA-BUTYROLACTONE;3-Hydroxydihydrofuran-2(3H)-one;3-hydroxyoxolan-2-one;2-Hydroxytetrahydrofuran-2-one;AKOS 224;Empagliflozin-C-1;3-Hydroxyoxolane-2-one;2-Hydroxybutyrolactone.;Alpha-hydroxybutylactone;a-Hydroxy-g-butyrolactone
- CBNumber:
- CB2193218
- Molecular Formula:
- C4H6O3
- Molecular Weight:
- 102.09
- MDL Number:
- MFCD00134268
- MOL File:
- 19444-84-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| α-Hydroxy-γ-butyrolactone technical grade | 364037 | 5g | $218 |
| 3-Hydroxydihydrofuran-2(3H)-one (99.999%, trace metals basis) min. 98.0 % | H1802 | 5G | $202 |
| alpha-Hydroxy-gamma-butyrolactone >98.0%(GC) | H0788 | 10g | $331 |
| alpha-Hydroxy-gamma-butyrolactone >98.0%(GC) | H0788 | 25g | $661 |
| Alpha-Hydroxy-Gamma-butyrolactone | TRC-B443818-500MG | 500mg | $103 |
| More product size | |||
| Boiling point | 133 °C/10 mmHg (lit.) |
|---|---|
| Density | 1.309 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform (Sparingly), Methanol (Slightly) |
| pka | 13.07±0.20(Predicted) |
| form | Viscous Liquid |
| color | Clear colorless to yellow |
| BRN | 80587 |
| InChI | InChI=1S/C4H6O3/c5-3-1-2-7-4(3)6/h3,5H,1-2H2 |
| InChIKey | FWIBCWKHNZBDLS-UHFFFAOYSA-N |
| SMILES | O1CCC(O)C1=O |
| LogP | -1.830 (est) |
| CAS DataBase Reference | 19444-84-9(CAS DataBase Reference) |
| FDA UNII | L5D4QZ05QR |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| PPE | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 23-24/25-36-26 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 3-10 | |||||||||
| HS Code | 29322090 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
ALPHA-HYDROXY-GAMMA-BUTYROLACTONE price More Price(60)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 364037 | α-Hydroxy-γ-butyrolactone technical grade | 19444-84-9 | 5g | $218 | 2026-04-30 | Buy |
| TCI Chemical | H1802 | 3-Hydroxydihydrofuran-2(3H)-one (99.999%, trace metals basis) min. 98.0 % | 19444-84-9 | 5G | $202 | 2026-04-30 | Buy |
| TCI Chemical | H0788 | alpha-Hydroxy-gamma-butyrolactone >98.0%(GC) | 19444-84-9 | 10g | $331 | 2026-04-30 | Buy |
| TCI Chemical | H0788 | alpha-Hydroxy-gamma-butyrolactone >98.0%(GC) | 19444-84-9 | 25g | $661 | 2026-04-30 | Buy |
| TRC | TRC-B443818-500MG | Alpha-Hydroxy-Gamma-butyrolactone | 19444-84-9 | 500mg | $103 | 2026-06-03 | Buy |
ALPHA-HYDROXY-GAMMA-BUTYROLACTONE Chemical Properties,Uses,Production
Chemical Properties
clear colorless to yellow viscous liquid
Uses
α-Hydroxy-γ-butyrolactone may be employed as starting reagent in the synthesis of series of seco-pseudonucleoside synthons via aminolysis. It may be employed as starting reagent in the synthesis of enantiomerically pure orthogonally protected δ-azaproline, via Mitsunobu reaction.
General Description
α-Hydroxy-γ-butyrolactone is a 5-membered cyclic ester. It was obtained via tin-conversion of biomass-derived 1,3-dihydroxyacetone (DHA) and formaldehyde.
Purification Methods
It has been purified by repeated fractionation and forms a colourless liquid. It has to be distilled at high vacuum; otherwise it will dehydrate. The acetox
ALPHA-HYDROXY-GAMMA-BUTYROLACTONE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Shaanxi Didu New Materials Co. Ltd | +86-86-17392712697 +8617792793228 | 1069@dideu.com | China | 8609 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Finetech Industry Limited | +86-27-8746-5837 +8619945049750 | info@finetechnology-ind.com | China | 9539 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
| Henan Alfa Chemical Co., Ltd | +8615838112936 | sale03@alfachem.cn | China | 9796 | 58 |
| changzhou huayang technology co., ltd | +8615250961469 | 2571773637@qq.com | China | 9653 | 58 |
View Lastest Price from ALPHA-HYDROXY-GAMMA-BUTYROLACTONE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-05-15 | ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
19444-84-9
|
$1.50 | 1g | 99.0% Min | 10 Tons | Shaanxi Didu New Materials Co. Ltd | |
![]() |
2026-03-20 | ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
19444-84-9
|
$10.00 | 1KG | 99% | 5tons | Hebei Chuanghai Biotechnology Co., Ltd | |
![]() |
2024-04-25 | 3-Hydroxydihydro-2(3H)-furanone
19444-84-9
|
$5.00 | 1kg | 99.92% | 50000tons | Ouhuang Engineering Materials (Hubei) Co., Ltd |
-

- ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
19444-84-9
- $1.50
- 99.0% Min
- Shaanxi Didu New Materials Co. Ltd
-

- ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
19444-84-9
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-

- 3-Hydroxydihydro-2(3H)-furanone
19444-84-9
- $5.00
- 99.92%
- Ouhuang Engineering Materials (Hubei) Co., Ltd
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