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ChemicalBook >> CAS DataBase List >>2-Chloro-4-iodopyridine-3-carboxaldehyde

2-Chloro-4-iodopyridine-3-carboxaldehyde

CAS No.
153034-90-3
Chemical Name:
2-Chloro-4-iodopyridine-3-carboxaldehyde
Synonyms
2-Chloro-4-iodonicotinaldehyde;2-CHLORO-4-IODO-PYRIDINE-3-CARBALDEHYDE;2-Chloro-4-iodo-3-pyridinecarboxaldehyde;CAS:153034-90-3;oro-4-iodo-pyridine-3-carbaL;2-CHLORO-3-FORMYL-4-IODOPYRIDINE;2-Chloro-4-Iodopyridine-3-Formaldehyde;2-CHLORO-4-IODOPYRIDINE-3-CARBOXALDEHYDE;3-Pyridinecarboxaldehyde, 2-chloro-4-iodo-;2-Chloro-4-iodo-pyridine-3-carbaldehyde ,97%
CBNumber:
CB2213208
Molecular Formula:
C6H3ClINO
Molecular Weight:
267.45
MDL Number:
MFCD03095294
MOL File:
153034-90-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 00:00:32
Product description Number Pack Size Price
2-Chloro-4-iodopyridine-3-carboxaldehyde 97% 722596 1g $208
2-Chloro-4-iodopyridine-3-carbaldehyde Asreported 270041 500mg $340
2-Chloro-4-iodopyridine-3-carbaldehyde Asreported 270041 1g $556
2-Chloro-4-iodopyridine-3-carbaldehyde Asreported 270041 2g $769
2-Chloro-4-iodopyridine-3-carbaldehyde Asreported 270041 5g $1308
More product size

2-Chloro-4-iodopyridine-3-carboxaldehyde Properties

Melting point 87-92 °C
Boiling point 326.6±42.0 °C(Predicted)
Density 2.083±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
form solid
pka -1.53±0.10(Predicted)
Appearance Light yellow to yellow Solid
Sensitive Air & Light Sensitive
InChI InChI=1S/C6H3ClINO/c7-6-4(3-10)5(8)1-2-9-6/h1-3H
InChIKey OPZCXONVRBYGHX-UHFFFAOYSA-N
SMILES C1(Cl)=NC=CC(I)=C1C=O
CAS DataBase Reference 153034-90-3(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-22
Safety Statements  26-36/37/39-37
WGK Germany  3
HazardClass  IRRITANT
HS Code  29333990
NFPA 704
1
2 0

2-Chloro-4-iodopyridine-3-carboxaldehyde price More Price(91)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 722596 2-Chloro-4-iodopyridine-3-carboxaldehyde 97% 153034-90-3 1g $208 2026-04-30 Buy
Usbiological 270041 2-Chloro-4-iodopyridine-3-carbaldehyde Asreported 153034-90-3 500mg $340 2026-06-03 Buy
Usbiological 270041 2-Chloro-4-iodopyridine-3-carbaldehyde Asreported 153034-90-3 1g $556 2026-06-03 Buy
Usbiological 270041 2-Chloro-4-iodopyridine-3-carbaldehyde Asreported 153034-90-3 2g $769 2026-06-03 Buy
Usbiological 270041 2-Chloro-4-iodopyridine-3-carbaldehyde Asreported 153034-90-3 5g $1308 2026-06-03 Buy
Product number Packaging Price Buy
722596 1g $208 Buy
270041 500mg $340 Buy
270041 1g $556 Buy
270041 2g $769 Buy
270041 5g $1308 Buy

2-Chloro-4-iodopyridine-3-carboxaldehyde Chemical Properties,Uses,Production

Uses

2-Chloro-4-iodopyridine-3-carboxaldehyde is an organic heterocyclic compound that can be used as a pharmaceutical intermediate.

Chemical Properties

Yellow-green solid

Synthesis

2-Chloro-3-iodopyridine

78607-36-0

Ethyl formate

109-94-4

2-Chloro-4-iodopyridine-3-carboxaldehyde

153034-90-3

Example 1: Synthesis of N-(2-(2,6-dichlorophenyl)-2H-pyrazolo[4,3-c]pyridin-4-yl)cyclopropanecarboxamide Step 1: Preparation of 2-chloro-4-iodonicotinaldehyde A solution of 2-chloro-3-iodopyridine (5.0 g, 21 mmol) in anhydrous THF (30 mL) was slowly added dropwise to a solution of lithium diisopropylammonium (15 mL, 30 mmol) in anhydrous THF (50 mL) that was pre-cooled to -78 °C. The reaction mixture was stirred continuously at -78 °C for 3 hours. Subsequently, ethyl formate (4.0 g, 54 mmol) was added to the reaction system and stirring was continued at the same temperature for 1.5 hours. Upon completion of the reaction, the reaction was quenched by the addition of water (10 mL), after which the mixture was slowly warmed to room temperature. THF was removed by distillation under reduced pressure after addition of 2 M HCl (50 mL).The aqueous phase was extracted with ethyl acetate (2 x 50 mL). The organic phases were combined, washed with brine, dried over anhydrous Na2SO4 and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography (eluent: ether/petroleum ether=1:4) to afford the target compound 2-chloro-4-iodonicotinaldehyde as a yellow solid (3.0 g, 54% yield). NMR (500MHz, CDCl3): δ10.22 (s, 1H), 8.09 (d, J=5.0Hz, 1H), 7.95 (d, J=5.0Hz, 1H).

References

[1] Synthetic Communications, 1996, vol. 26, # 23, p. 4421 - 4436
[2] Journal of Organic Chemistry, 1993, vol. 58, # 27, p. 7832 - 7838
[3] Journal of Heterocyclic Chemistry, 2001, vol. 38, # 5, p. 1039 - 1044
[4] Patent: WO2012/66061, 2012, A1. Location in patent: Page/Page column 76-77

153034-86-7
109-94-4
153034-90-3
Synthesis of 2-Chloro-4-iodopyridine-3-carboxaldehyde from 2-Chloro-4-iodopyridine and Ethyl formate

2-Chloro-4-iodopyridine-3-carboxaldehyde Preparation Products And Raw materials

Global( 191)Suppliers
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Xi'an Yutbon Pharmaceutical Technology Co., Ltd
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Jinan Finer Chemical Co., Ltd 		+86-531-88989536 +86-15508631887 sales@finerchem.com China 2950 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49979 58

View Lastest Price from 2-Chloro-4-iodopyridine-3-carboxaldehyde manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Chloro-4-iodopyridine-3-carboxaldehyde pictures 2025-11-18 2-Chloro-4-iodopyridine-3-carboxaldehyde
153034-90-3
 $1.10 1g 99.00% 100 Tons min Dideu Industries Group Limited
2-Chloro-4-iodopyridine-3-carboxaldehyde pictures 2025-04-04 2-Chloro-4-iodopyridine-3-carboxaldehyde
153034-90-3
 1KG 98% 1ton Henan Aochuang Chemical Co.,Ltd.
2-Chloro-4-iodopyridine-3-carboxaldehyde pictures 2022-02-09 2-Chloro-4-iodopyridine-3-carboxaldehyde
153034-90-3
 1KG 98.1% 100 tons Honest Joy Holdings Limited

2-Chloro-4-iodopyridine-3-carboxaldehyde Spectrum

2-CHLORO-4-IODOPYRIDINE-3-CARBOXALDEHYDE 2-CHLORO-3-FORMYL-4-IODOPYRIDINE 2-Chloro-3-formyl-4-iodopyridine, 2-Chloro-4-iodopyridine-3-carboxaldehyde 2-Chloro-4-iodo-pyridine-3-carbaldehyde ,97% 2-Chloro-4-Iodopyridine-3-Formaldehyde oro-4-iodo-pyridine-3-carbaL 3-Pyridinecarboxaldehyde, 2-chloro-4-iodo- 2-Chloro-4-iodopyridine-3-carboxaldehyde ISO 9001：2015 REACH CAS:153034-90-3 2-Chloro-4-iodonicotinaldehyde 2-Chloro-4-iodo-3-pyridinecarboxaldehyde 2-CHLORO-4-IODO-PYRIDINE-3-CARBALDEHYDE 153034-90-3 153034-90-4 C6H3CllNO C6H3ClINO Heterocycle-Pyridine series Boronic Acid Aldehydes Building Blocks C1 to C6 C5 to C6 C6 to C7 Carbonyl Compounds Chemical Synthesis Halogenated Heterocycles Heterocyclic Building Blocks Organic Building Blocks Pyridine Pyridines
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