2-Amino-4,5-dichlorophenol
- CAS No.
- 28443-57-4
- Chemical Name:
- 2-Amino-4,5-dichlorophenol
- Synonyms
- Lenvatinib Impurity 87;2-AMINO-4,5-DICHLORPHENOL;2-Amino-4,5-dichlorophenol;Phenol, 2-amino-4,5-dichloro-;4,5-Dichloro-2-hydroxyaniline
- CBNumber:
- CB22205764
- Molecular Formula:
- C6H5Cl2NO
- Molecular Weight:
- 178.02
- MDL Number:
- MFCD12406838
- MOL File:
- 28443-57-4.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-Amino-4,5-dichlorophenol | DBA44357 | 2.5g | $383.5 |
| 2-Amino-4,5-dichlorophenol ≥95% | OR16946 | 250mg | $39 |
| 2-Amino-4,5-dichlorophenol ≥95% | OR16946 | 1g | $89 |
| 2-Amino-4,5-dichlorophenol 98% | AS47563 | 1g | $136 |
| 2-Amino-4,5-dichlorophenol ≥95% | OR16946 | 5g | $266 |
| More product size | |||
| Melting point | 174-175 °C |
|---|---|
| Boiling point | 309.1±42.0 °C(Predicted) |
| Density | 1.560±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| form | powder |
| pka | 8.36±0.23(Predicted) |
| color | Very dark beige to very dark brown |
| EPA Substance Registry System | Phenol, 2-amino-4,5-dichloro- (28443-57-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36/37/39 |
| HS Code | 29089990 |
2-Amino-4,5-dichlorophenol price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | DBA44357 | 2-Amino-4,5-dichlorophenol | 28443-57-4 | 2.5g | $383.5 | 2026-06-04 | Buy |
| Apolloscientific | OR16946 | 2-Amino-4,5-dichlorophenol ≥95% | 28443-57-4 | 250mg | $39 | 2026-06-04 | Buy |
| Apolloscientific | OR16946 | 2-Amino-4,5-dichlorophenol ≥95% | 28443-57-4 | 1g | $89 | 2026-06-04 | Buy |
| Activate Scientific | AS47563 | 2-Amino-4,5-dichlorophenol 98% | 28443-57-4 | 1g | $136 | 2026-06-04 | Buy |
| Apolloscientific | OR16946 | 2-Amino-4,5-dichlorophenol ≥95% | 28443-57-4 | 5g | $266 | 2026-06-04 | Buy |
2-Amino-4,5-dichlorophenol Chemical Properties,Uses,Production
Synthesis
39224-65-2
28443-57-4
The general procedure for the synthesis of 2-hydroxy-4,5-dichloroaniline from 4,5-dichloro-2-nitrophenol was as follows: to a stirred mixed solution of 4,5-dichloro-2-nitrophenol (15 g, 72 mmol) in acetic acid (150 mL) and water (450 mL) was added powdered iron (16 g, 285 mmol) in batches. The reaction mixture was stirred continuously at 50 °C for 2 hours. Upon completion of the reaction, the mixture was cooled to room temperature and subjected to filtration operation and the filter cake was washed with ethyl acetate. The filtrate was subsequently extracted with ethyl acetate. The combined organic layers were washed sequentially with water, NaHCO3 (aq.) and brine, dried over Na2SO4 and concentrated under vacuum to give the final target product 2-hydroxy-4,5-dichloroaniline (10 g, 78% yield).
References
[1] Journal of Organic Chemistry, 1996, vol. 61, # 10, p. 3289 - 3297
[2] Patent: US2014/288045, 2014, A1. Location in patent: Paragraph 0456
[3] European Journal of Medicinal Chemistry, 2012, vol. 56, p. 108 - 119
[4] Patent: WO2018/37223, 2018, A1. Location in patent: Page/Page column 81
[5] Journal of the Chemical Society, 1956, p. 4727,4730
2-Amino-4,5-dichlorophenol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Fluoropharm Co., Ltd. | +86-0571-85586753 +86-13336034509 | sales@fluoropharm.com | China | 1445 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10000 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14304 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| Aromsyn Co., Ltd. | +86-0571-85585865 +8613336024896 | CB@aromsyn.com | China | 19183 | 58 |
| Aceschem Inc. | +1-817863-6948 +1-（817）863-6948 | sales@aceschem.com | United States | 19632 | 58 |
| Supplier | Advantage |
|---|---|
| Capot Chemical Co.,Ltd. | 60 |
| Fluoropharm Co., Ltd. | 60 |
| ATK CHEMICAL COMPANY LIMITED | 60 |
| career henan chemical co | 58 |
| Fuxin Pharmaceutical | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 58 |
| Win-Win chemical CO., Limited | 58 |
| Labnetwork lnc. | 58 |
| Aromsyn Co., Ltd. | 58 |
| Aceschem Inc. | 58 |
View Lastest Price from 2-Amino-4,5-dichlorophenol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-12-20 | 2-Amino-4,5-dichlorophenol
28443-57-4
|
$1.00 | 1g | 99% | 1000kgs | Career Henan Chemical Co |
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- 2-Amino-4,5-dichlorophenol
28443-57-4
- $1.00
- 99%
- Career Henan Chemical Co
