Methyl 5-Benzyloxy-4-Methoxy-2-nitrobenzoate
- CAS No.
- 164161-49-3
- Chemical Name:
- Methyl 5-Benzyloxy-4-Methoxy-2-nitrobenzoate
- Synonyms
- Methyl 5-Benzyloxy-4-Methoxy-2-nitrobenzoate;Methyl 4-methoxy-2-nitro-5-(phenylmethoxy)benzoate;Benzoicacid,4-Methoxy-2-nitro-5-(phenylMethoxy)-,Methylester
- CBNumber:
- CB22597368
- Molecular Formula:
- C16H15NO6
- Molecular Weight:
- 317.29
- MDL Number:
- MFCD17168894
- MOL File:
- 164161-49-3.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Methyl 5-benzyloxy-4-methoxy-2-nitrobenzoate | 074744 | 1.00g | $462 |
| Methyl 5-benzyloxy-4-methoxy-2-nitrobenzoate | 074744 | 5.00g | $1298 |
| Methyl 5-benzyloxy-4-methoxy-2-nitrobenzoate 95+% | M58666 | 250mg | $54 |
| Methyl 5-benzyloxy-4-methoxy-2-nitrobenzoate 95+% | M58666 | 1g | $58 |
| Methyl 5-benzyloxy-4-methoxy-2-nitrobenzoate 95+% | M58666 | 5g | $60 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
Methyl 5-Benzyloxy-4-Methoxy-2-nitrobenzoate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 074744 | Methyl 5-benzyloxy-4-methoxy-2-nitrobenzoate | 164161-49-3 | 1.00g | $462 | 2026-05-18 | Buy |
| Matrix Scientific | 074744 | Methyl 5-benzyloxy-4-methoxy-2-nitrobenzoate | 164161-49-3 | 5.00g | $1298 | 2026-05-18 | Buy |
| Synthonix | M58666 | Methyl 5-benzyloxy-4-methoxy-2-nitrobenzoate 95+% | 164161-49-3 | 250mg | $54 | 2026-05-06 | Buy |
| Synthonix | M58666 | Methyl 5-benzyloxy-4-methoxy-2-nitrobenzoate 95+% | 164161-49-3 | 1g | $58 | 2026-05-06 | Buy |
| Synthonix | M58666 | Methyl 5-benzyloxy-4-methoxy-2-nitrobenzoate 95+% | 164161-49-3 | 5g | $60 | 2026-05-06 | Buy |
Methyl 5-Benzyloxy-4-Methoxy-2-nitrobenzoate Chemical Properties,Uses,Production
Synthesis
215659-03-3
100-39-0
164161-49-3
The reaction was carried out with methyl 5-hydroxy-4-methoxy-2-nitrobenzoate (15.4 g, 68 mmol) and benzyl bromide (9.7 mL, 82 mmol) in the presence of cesium carbonate (44 g, 136 mmol) with stirring at room temperature in DMSO (200 mL) for 24 hours. After completion of the reaction, the reaction mixture was diluted with ethyl acetate (~2 L) and n-butanol (~100 mL). The organic layer was washed sequentially with water and brine, dried with magnesium sulfate, filtered and concentrated. The residue was purified by silica gel column chromatography (eluent ratio from 1:5 to 2:1 ethyl acetate-hexane) to afford methyl 2-nitro-4-methoxy-5-benzyloxybenzoate 20.2 g in 94% yield; MS (AP/CI): 286.1 (M + H)+.
References
[1] Patent: WO2008/20302, 2008, A2. Location in patent: Page/Page column 28
[2] Journal of Medicinal Chemistry, 2011, vol. 54, # 13, p. 4536 - 4547
Methyl 5-Benzyloxy-4-Methoxy-2-nitrobenzoate Preparation Products And Raw materials
Methyl 5-Benzyloxy-4-Methoxy-2-nitrobenzoate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42934 | 64 |
| Shanghai civi chemical technology co.,Ltd | 86-21-34053660 | sale@labgogo.com | China | 9865 | 52 |
| Shanghai Topbiochem Technology Co., Ltd | +86-21-60341587 | sales@topbiochem.com | China | 6175 | 58 |
| Shanghai Witofly Chemical Co.,Ltd | sales@witofly.com | China | 2864 | 52 | |
| Shanghai Raise Chemical Technology Co.,Ltd | +86-021-50935922 | China | 7865 | 55 | |
| Hangzhou Trylead Chemical Technology Co.,LTD | 0571-87086220 13516718938 | zyf@trylead-chem.com | China | 299 | 64 |
| ShangHai KenEn Chemical Technology Co., Ltd. | 13120367189 | mychess007@163.com | China | 1994 | 55 |
