5-Chloro-2,3,3-trimethyl-3H-indole
- CAS No.
- 25981-83-3
- Chemical Name:
- 5-Chloro-2,3,3-trimethyl-3H-indole
- Synonyms
- -3H-indoL;AURORA KA-3417;oro-2,3,3-trimethyL;5-CHLORO-2,3,3-TRIMETHYLINDOLE;5-CHLORO-2,3,3-TRIMETHYLINDOLINE;5-Chlor-2,3,3-trimethyl-3H-indol;5-chloro-2,3,3-trimethyl-3h-indol;2,3,3-TRIMETHYL-5-CHLORO-3H-INDOLE;5-CHLORO-2,3,3-TRIMETHYL-3H-INDOLE;5-CHLORO-1,3,3-TRIMETHYL-3H-INDOLE
- CBNumber:
- CB2349415
- Molecular Formula:
- C11H12ClN
- Molecular Weight:
- 193.67
- MDL Number:
- MFCD00126966
- MOL File:
- 25981-83-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 5-Chloro-2,3,3-Trimethyl-3H-Indole Asreported | 269947 | 2g | $353 |
| 5-Chloro-2,3,3-Trimethyl-3H-Indole Asreported | 269947 | 5g | $575 |
| 5-Chloro-2,3,3-Trimethyl-3H-Indole Asreported | 269947 | 10g | $801 |
| 5-Chloro-2,3,3-Trimethyl-3H-Indole Asreported | 269947 | 25g | $1118 |
| 5-Chloro-2,3,3-trimethyl-3H-indole >98% | OR10207 | 1g | $21 |
| More product size | |||
| Boiling point | 271.1±40.0 °C(Predicted) |
|---|---|
| Density | 1.083 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 4.87±0.40(Predicted) |
| form | solid |
| color | Red |
| InChI | InChI=1S/C11H12ClN/c1-7-11(2,3)9-6-8(12)4-5-10(9)13-7/h4-6H,1-3H3 |
| InChIKey | GSKATGIMEUGNJN-UHFFFAOYSA-N |
| SMILES | N1C2=C(C=C(Cl)C=C2)C(C)(C)C=1C |
| CAS DataBase Reference | 25981-83-3(CAS DataBase Reference) |
| EPA Substance Registry System | 3H-Indole, 5-chloro-2,3,3-trimethyl- (25981-83-3) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-37/39 |
| WGK Germany | 3 |
| TSCA | TSCA listed |
| HS Code | 2933998090 |
5-Chloro-2,3,3-trimethyl-3H-indole price More Price(54)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 269947 | 5-Chloro-2,3,3-Trimethyl-3H-Indole Asreported | 25981-83-3 | 2g | $353 | 2026-06-03 | Buy |
| Usbiological | 269947 | 5-Chloro-2,3,3-Trimethyl-3H-Indole Asreported | 25981-83-3 | 5g | $575 | 2026-06-03 | Buy |
| Usbiological | 269947 | 5-Chloro-2,3,3-Trimethyl-3H-Indole Asreported | 25981-83-3 | 10g | $801 | 2026-06-03 | Buy |
| Usbiological | 269947 | 5-Chloro-2,3,3-Trimethyl-3H-Indole Asreported | 25981-83-3 | 25g | $1118 | 2026-06-03 | Buy |
| Apolloscientific | OR10207 | 5-Chloro-2,3,3-trimethyl-3H-indole >98% | 25981-83-3 | 1g | $21 | 2026-06-04 | Buy |
5-Chloro-2,3,3-trimethyl-3H-indole Chemical Properties,Uses,Production
Synthesis
563-80-4
1073-70-7
25981-83-3
GENERAL METHOD: 3-methyl-2-butanone (1.2 eq.) and p-chlorophenylhydrazine hydrochloride (1 g) were sequentially added to a 10 mL microwave reaction tube equipped with a magnetic stirrer. Subsequently, deionized water (3 mL) and sulfuric acid (0.1 equiv) were added to the reaction mixture. The reaction tube was sealed and placed in a microwave reactor and radiated at 100 °C for 10 min until the feedstock was completely converted. Upon completion of the reaction, the aqueous layer was removed and saturated sodium bicarbonate solution (3 mL) was added to the residue to neutralize the reaction solution. The mixture was sonicated for 10 min to completely quench the residual acidity. The organic layer was separated and the resulting oily product was dissolved in a minimum volume of dichloromethane and dried by adding anhydrous sodium sulfate for 30 minutes. After gravity filtration, the filtrate was concentrated to obtain 5-chloro-2,3,3-trimethylindole in quantitative yield.
References
[1] Dyes and Pigments, 2015, vol. 113, p. 27 - 37
[2] Journal of Heterocyclic Chemistry, 2002, vol. 39, # 2, p. 263 - 269
[3] Advanced Synthesis and Catalysis, 2015, vol. 357, # 8, p. 1692 - 1696
[4] Patent: WO2004/39894, 2004, A2. Location in patent: Page 37
5-Chloro-2,3,3-trimethyl-3H-indole Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Junwee Chemical co., Ltd. | +86-571-85808636 +86-13958122542 | sales@junweechem.com | China | 823 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14014 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 8740 | 58 |
| AFINE CHEMICALS LIMITED | +86-571-85134551 | info@afinechem.com | China | 15083 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52704 | 58 |
View Lastest Price from 5-Chloro-2,3,3-trimethyl-3H-indole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-04 | 5-Chloro-2,3,3-trimethyl-3H-indole
25981-83-3
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
 |
2019-07-06 | 5-Chloro-2,3,3-trimethyl-3H-indole
25981-83-3
|
$1.00 | 1kg | 99% | Career Henan Chemical Co |
-
- 5-Chloro-2,3,3-trimethyl-3H-indole
25981-83-3
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 5-Chloro-2,3,3-trimethyl-3H-indole
25981-83-3
- $1.00
- 99%
- Career Henan Chemical Co
