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ChemicalBook >> CAS DataBase List >>METHYL 4-AMINO-6-INDOLECARBOXYLATE

METHYL 4-AMINO-6-INDOLECARBOXYLATE

CAS No.
121561-15-7
Chemical Name:
METHYL 4-AMINO-6-INDOLECARBOXYLATE
Synonyms
4-AMINO-6-METHOXYCARBONYL INDOLE;4-AMino-6-Methylcarboxylateindole;METHYL 4-AMINO-6-INDOLECARBOXYLATE;Methyl 4-AMinoindole-6-carboxylate;Methyl 4-AMino-6-indolecarboxylate Hy;Methyl4-amino-1H-indole-6-carboxylate;4-AMINOINDOLE-6-CARBOXYLIC ACID METHYL ESTER;METHYL 4-AMINO-6-INDOLECARBOXYLATE USP/EP/BP;4-AMINO-6-INDOLE CARBOXYLIC ACID METHYL ESTER;Methyl 4-Amino-6-indolecarboxylate Hydrochloride
CBNumber:
CB2689535
Molecular Formula:
C10H10N2O2
Molecular Weight:
190.2
MDL Number:
MFCD00461176
MOL File:
121561-15-7.mol
MSDS File:
SDS
Last updated:2026-05-28 00:39:31
Product description Number Pack Size Price
Methyl 4-amino-1H-indole-6-carboxylate 132948 250.00mg $20
Methyl 4-amino-1H-indole-6-carboxylate 132948 1.00g $64
Methyl 4-amino-1H-indole-6-carboxylate 132948 5.00g $320
methyl 4-amino-1H-indole-6-carboxylate 97.0% M17605 250mg $26
methyl 4-amino-1H-indole-6-carboxylate 97.0% M17605 1g $70
More product size

METHYL 4-AMINO-6-INDOLECARBOXYLATE Properties

Melting point 160-163 °C(Solv: benzene (71-43-2))
Boiling point 429.8±25.0 °C(Predicted)
Density 1.339±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka 17.03±0.30(Predicted)
Appearance Light brown to brown Solid
CAS DataBase Reference 121561-15-7(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405-P501

METHYL 4-AMINO-6-INDOLECARBOXYLATE price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 132948 Methyl 4-amino-1H-indole-6-carboxylate 121561-15-7 250.00mg $20 2026-05-18 Buy
Matrix Scientific 132948 Methyl 4-amino-1H-indole-6-carboxylate 121561-15-7 1.00g $64 2026-05-18 Buy
Matrix Scientific 132948 Methyl 4-amino-1H-indole-6-carboxylate 121561-15-7 5.00g $320 2026-05-18 Buy
Synthonix M17605 methyl 4-amino-1H-indole-6-carboxylate 97.0% 121561-15-7 250mg $26 2026-05-06 Buy
Synthonix M17605 methyl 4-amino-1H-indole-6-carboxylate 97.0% 121561-15-7 1g $70 2026-05-06 Buy
Product number Packaging Price Buy
132948 250.00mg $20 Buy
132948 1.00g $64 Buy
132948 5.00g $320 Buy
M17605 250mg $26 Buy
M17605 1g $70 Buy

METHYL 4-AMINO-6-INDOLECARBOXYLATE Chemical Properties,Uses,Production

Uses

In the pharmaceutical field, methyl 4-amino-6-indolecarboxylate is mainly used as an organic synthesis intermediate to synthesize a variety of drug compounds, such as methyl 4-amino-6-indolecarboxylate hydrochloride, which is used in drug synthesis.

Synthesis

(E)-Methyl 4-(2-(diMethylaMino)vinyl)-3,5-dinitrobenzoate

597562-13-5

METHYL 4-AMINO-6-INDOLECARBOXYLATE

121561-15-7

To a solution of methyl 4-[(E)-2-(dimethylamino)vinyl]-3,5-dinitrobenzoate (D200) (10 g, 34 mmol, 1 eq.) in methanol (250 ml) was added 10% palladium charcoal (50% wet, 1.0 g, 5% w/w). The reaction mixture was stirred under hydrogen atmosphere for 7 hours. Upon completion of the reaction, the catalyst was removed by filtration through a diatomaceous earth pad and the filtrate was concentrated under reduced pressure. The residue was ground with ethyl acetate/isohexane mixed solvent to afford methyl 4-amino-1H-indole-6-carboxylate (D201) (5 g, 77% yield) as a dark pink solid. Mass spectrometry analysis showed [M+H]+ = 191.0 and retention time (RT) = 1.20 min.

References

[1] Tetrahedron Letters, 2007, vol. 48, # 45, p. 7990 - 7993
[2] Patent: WO2004/50619, 2004, A1. Location in patent: Page 57
[3] Patent: WO2005/58915, 2005, A1. Location in patent: Page/Page column 18

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View Lastest Price from METHYL 4-AMINO-6-INDOLECARBOXYLATE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
METHYL 4-AMINO-6-INDOLECARBOXYLATE pictures 2020-01-09 METHYL 4-AMINO-6-INDOLECARBOXYLATE
121561-15-7
$1.00 1KG 99% 200kg Career Henan Chemical Co
Methyl 4-Amino-6-indolecarboxylate Hydrochloride 4-AMINO-6-METHOXYCARBONYL INDOLE Methyl4-amino-1H-indole-6-carboxylate 4-amino-6-indole carboxylic acid methyl ester ,95% 1H-Indole-6-carboxylic acid, 4-aMino-, Methyl ester 4-AMino-6-Methylcarboxylateindole Methyl 4-AMino-6-indolecarboxylate Hy Methyl 4-AMinoindole-6-carboxylate 4-AMINOINDOLE-6-CARBOXYLIC ACID METHYL ESTER 4-AMINO-6-INDOLE CARBOXYLIC ACID METHYL ESTER METHYL 4-AMINO-6-INDOLECARBOXYLATE 1H-Indole-6-carboxylicacid,4-amino-,methylester(9CI) 4-amino-1H-indole-6-carboxylic acid methyl ester hydrochloride METHYL 4-AMINO-6-INDOLECARBOXYLATE USP/EP/BP 121561-15-7 12156-15-7 Acids and Derivatives Heterocycles Indole/indoline/oxindole Indole Heterocyclic Compounds AMINOACID
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