ETHYL 2-CHLORO-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBOXYLATE
- CAS No.
- 72850-52-3
- Chemical Name:
- ETHYL 2-CHLORO-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBOXYLATE
- Synonyms
- Ethyl 2-chloro-4-(trifluoroMethyl)thiazole-5-carboxylate;ETHYL 2-CHLORO-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBOXYLATE;2-chloro-4-trifluoromethyl-thiazol-5-carboxylic acid-ethyl ester;2-CHLORO-4-TRIFLUOROMETHYL-THIAZOLE-5-CARBOXYLIC ACID ETHYL ESTER;2-chloro-4-(trifluoromethyl)-5-thiazolecarboxylic acid ethyl ester;5-Thiazolecarboxylic acid, 2-chloro-4-(trifluoromethyl)-, ethyl ester
- CBNumber:
- CB3109311
- Molecular Formula:
- C7H5ClF3NO2S
- Molecular Weight:
- 259.63
- MDL Number:
- MFCD02956778
- MOL File:
- 72850-52-3.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Ethyl 2-chloro-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate ≥95% | PC14280 | 100mg | $21 |
| Ethyl 2-chloro-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate ≥95% | PC14280 | 250mg | $24 |
| Ethyl 2-chloro-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate ≥95% | PC14280 | 100mg | $21 |
| Ethyl 2-chloro-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate ≥95% | PC14280 | 250mg | $24 |
| Ethyl 2-chloro-4-(trifluoromethyl)thiazole-5-carboxylate | 306643 | 100.00mg | $15 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312+H332-H315-H319-H335 |
| Precautionary statements | P260-P280-P312 |
| Hazard Codes | Xi |
| HazardClass | IRRITANT |
| HS Code | 2934100090 |
ETHYL 2-CHLORO-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBOXYLATE price More Price(40)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC14280 | Ethyl 2-chloro-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate ≥95% | 72850-52-3 | 100mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | PC14280 | Ethyl 2-chloro-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate ≥95% | 72850-52-3 | 250mg | $24 | 2026-06-04 | Buy |
| Apolloscientific | PC14280 | Ethyl 2-chloro-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate ≥95% | 72850-52-3 | 100mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | PC14280 | Ethyl 2-chloro-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate ≥95% | 72850-52-3 | 250mg | $24 | 2026-06-04 | Buy |
| Matrix Scientific | 306643 | Ethyl 2-chloro-4-(trifluoromethyl)thiazole-5-carboxylate | 72850-52-3 | 100.00mg | $15 | 2026-05-19 | Buy |
ETHYL 2-CHLORO-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBOXYLATE Chemical Properties,Uses,Production
Synthesis
344-72-9
110-46-3
72850-52-3
General procedure: preparation of ethyl 2-chloro-4-(trifluoromethyl)thiazole-5-carboxylate; ethyl 2-amino-4-(trifluoromethyl)thiazole-5-carboxylate (1.0 g, 4.16 mmol) was slowly added to CuCl2 (671 mg, 4.99 mmol) and isoamyl nitrite (732 mg, 6.24 mmol) in acetonitrile (10 ml) at 0°C in a in the mixture. The reaction mixture was stirred at room temperature for 1 hour and then heated to 50 °C to continue the reaction for 1 hour. After completion of the reaction, most of the solvent was removed under reduced pressure and the residue was poured into a mixture of ice and concentrated hydrochloric acid. The mixture was extracted with dichloromethane, the organic layer was washed with brine, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The crude product was purified by fast silica gel column chromatography (eluent: hexane/ethyl acetate = 20:1) to afford the target compound ethyl 2-chloro-4-(trifluoromethyl)thiazole-5-carboxylate (762 mg, 71% yield).1H NMR (300 MHz, DMSO-d6) δ 1.26 (t, J=7.0 Hz, 3H), 4.31 (q, J=7.0 Hz, 2H).
References
[1] Patent: WO2010/56588, 2010, A1. Location in patent: Page/Page column 13
ETHYL 2-CHLORO-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBOXYLATE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 16512 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Longyan Tianhua Biological Technology Co., Ltd | 0086 18039857276 18039857276 | CHINA | 2783 | 58 | |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| Coresyn Pharmatech Co., Ltd. | +86-571-86626709 +86-18157142896 | cbc@coresyn.com | China | 9984 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Cochemical Co. Ltd. | +86-029-86115547 +86-17791676824 | sales@cochemical.com | China | 3952 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53803 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
View Lastest Price from ETHYL 2-CHLORO-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBOXYLATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-04-17 | ETHYL 2-CHLORO-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBOXYLATE
72850-52-3
|
$1.60-9.60 | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
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2020-11-16 | 5-(trifluoromethyl)thiazol-2-amine
72850-52-3
|
$12.00 | 25Kg/Bag | 99% | 20 Tons | Longyan Tianhua Biological Technology Co., Ltd |
-

- ETHYL 2-CHLORO-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBOXYLATE
72850-52-3
- $1.60-9.60
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-

- 5-(trifluoromethyl)thiazol-2-amine
72850-52-3
- $12.00
- 99%
- Longyan Tianhua Biological Technology Co., Ltd





