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ChemicalBook >> CAS DataBase List >>2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone

CAS No.
204205-33-4
Chemical Name:
2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone
Synonyms
2-broMo-1-cyclopropyl-2-(2-fluorophenyl)ethan-1-one;PL-02;Prasugrel IMP;Prasugrel IMpurity;Pragrel intermediate;Prasugrel Impurity 46;Prasugrel Intermediate 4;2-Bromo-2-(2-fluorophenyl);Chemical intermediate for Prasugrel;Prasugrel alpha-Bromo 2-Fluoro Impurity
CBNumber:
CB31872230
Molecular Formula:
C11H10BrFO
Molecular Weight:
257.1
MDL Number:
MFCD11977644
MOL File:
204205-33-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 01:02:06
Product description Number Pack Size Price
2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone B6031 1G $34
2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone B6031 5G $117
2-?Bromo-?2-?(2-?fluorophenyl)?-?1-?cyclopropylethanone (90% purity) TRC-B688795-5G 5g $849
2-?Bromo-?2-?(2-?fluorophenyl)?-?1-?cyclopropylethanone (90% purity) TRC-B688795-250MG 250mg $103
2-?Bromo-?2-?(2-?fluorophenyl)?-?1-?cyclopropylethanone (90% purity) TRC-B688795-1G 1g $288
More product size

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone Properties

Boiling point 293.0±25.0 °C(Predicted)
Density 1.574±0.06 g/cm3(Predicted)
Flash point 131°
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Chloroform (Sparingly), Ethyl Acetate (Slightly)
form Oil to Low-Melting Solid
form Oil to Low-Melting Solid
color Yellow to Light Brown
optical activity 0.0900°(C=1g/100mL, CHCL3, 20°C, 589nm)
CAS DataBase Reference 204205-33-4(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
HS Code  2914.79.4000
NFPA 704
1
0 0

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone price More Price(68)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical B6031 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone 204205-33-4 1G $34 2026-04-30 Buy
TCI Chemical B6031 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone 204205-33-4 5G $117 2026-04-30 Buy
TRC TRC-B688795-5G 2-?Bromo-?2-?(2-?fluorophenyl)?-?1-?cyclopropylethanone (90% purity) 204205-33-4 5g $849 2026-06-03 Buy
TRC TRC-B688795-250MG 2-?Bromo-?2-?(2-?fluorophenyl)?-?1-?cyclopropylethanone (90% purity) 204205-33-4 250mg $103 2026-06-03 Buy
TRC TRC-B688795-1G 2-?Bromo-?2-?(2-?fluorophenyl)?-?1-?cyclopropylethanone (90% purity) 204205-33-4 1g $288 2026-06-03 Buy
Product number Packaging Price Buy
B6031 1G $34 Buy
B6031 5G $117 Buy
TRC-B688795-5G 5g $849 Buy
TRC-B688795-250MG 250mg $103 Buy
TRC-B688795-1G 1g $288 Buy

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone Chemical Properties,Uses,Production

Uses

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone is a reagent used in the synthesis of potent anti-oxidant agents.

Synthesis

Cyclopropyl 2-fluorobenzyl ketone

150322-73-9

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone

204205-33-4

General procedure for the synthesis of 2-bromo-2-(2-fluorophenyl)-1-cyclopropylethanone from 1-cyclopropyl-2-(2-fluorophenyl)ethanone: 1-cyclopropyl-2-(2-fluorophenyl)ethanone (17.8 g, 100 mmol), iodine monobromide (62 g, 300 mmol), and 1-butyl-3-methylimidazolium bromide (8.7 g, 40 mmol) were dissolved in 150 mL of anhydrous tetrahydrofuran. The reaction was stirred at 40 °C for 4 hours. After completion of the reaction, the mixture was cooled to room temperature and the reaction was quenched by the addition of ice water. The reaction mixture was extracted with ethyl acetate and the organic phase was washed with saturated sodium bisulfite solution. The organic phase was concentrated and purified by recrystallization from ethanol to give 2-bromo-2-(2-fluorophenyl)-1-cyclopropylethanone (24.5 g, 95.3% yield, 99.73% purity).

References

[1] Patent: CN105884793, 2016, A. Location in patent: Paragraph 0033; 0034; 0035
[2] Patent: WO2013/14295, 2013, A1. Location in patent: Page/Page column 19-20
[3] Patent: WO2009/122440, 2009, A1. Location in patent: Page/Page column 31
[4] Patent: CN105884599, 2016, A. Location in patent: Paragraph 0025; 0062-0064
[5] Patent: CN104418718, 2018, B. Location in patent: Paragraph 0040; 0044; 0047; 0048; 0052; 0056

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone Preparation Products And Raw materials

Global( 247)Suppliers
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Capot Chemical Co.,Ltd.
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CONIER CHEM AND PHARMA LIMITED
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View Lastest Price from 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone pictures 2026-06-15 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone
204205-33-4
$23.00 1kg 99% 50mt Jinan Finer Chemical Co., Ltd
2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone pictures 2026-04-09 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone
204205-33-4
1KG Ton 93%+ 2 tons/month ZHUHAI HRD PHARMACEUTICAL CO., LTD.
2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone pictures 2021-07-13 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone
204205-33-4
$10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone Spectrum

Prasugrel Intermediate 4 2-Bromo-2-(2-fluorophenyl) Ethanone, 2-bromo-1-cyclopropyl-2-(2-fluorophenyl)- 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone Cylopropylcarbonyl-2-flurobenzyl bromide 2-Bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone Chemical intermediate for Prasugrel Prasugrel IMpurity PL-02 α - cyclopropyl carbonyl -2- fluorine benzyl bromide Prasugrel IMP 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone in stock Factory 2-fluoro-α-cyclopropyl carbonyl benzyl bromide 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone (90% purity) Prasugrel alpha-Bromo 2-Fluoro Impurity Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone Cyclopropylcarbonyl-2-fluorobenzyl bromide 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanoneQ: What is 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone Q: What is the CAS Number of 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone Q: What is the storage condition of 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone Q: What are the applications of 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone 204205-33-4 2-broMo-1-cyclopropyl-2-(2-fluorophenyl)ethan-1-one α-(Cyclopropylcarbonyl)-2-fluorobenzyl bromide Prasugrel Impurity 46 Pragrel intermediate Prasugrel Impurity 12 2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethan-1-one 2-Bromo-2-(2-fluorophenyl)cyclopropanone 204205-33-4 C11H10BrFO
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