2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone
- CAS No.
- 204205-33-4
- Chemical Name:
- 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone
- Synonyms
- 2-broMo-1-cyclopropyl-2-(2-fluorophenyl)ethan-1-one;PL-02;Prasugrel IMP;Prasugrel IMpurity;Pragrel intermediate;Prasugrel Impurity 46;Prasugrel Intermediate 4;2-Bromo-2-(2-fluorophenyl);Chemical intermediate for Prasugrel;Prasugrel alpha-Bromo 2-Fluoro Impurity
- CBNumber:
- CB31872230
- Molecular Formula:
- C11H10BrFO
- Molecular Weight:
- 257.1
- MDL Number:
- MFCD11977644
- MOL File:
- 204205-33-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone | B6031 | 1G | $34 |
| 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone | B6031 | 5G | $117 |
| 2-?Bromo-?2-?(2-?fluorophenyl)?-?1-?cyclopropylethanone (90% purity) | TRC-B688795-5G | 5g | $849 |
| 2-?Bromo-?2-?(2-?fluorophenyl)?-?1-?cyclopropylethanone (90% purity) | TRC-B688795-250MG | 250mg | $103 |
| 2-?Bromo-?2-?(2-?fluorophenyl)?-?1-?cyclopropylethanone (90% purity) | TRC-B688795-1G | 1g | $288 |
| More product size | |||
| Boiling point | 293.0±25.0 °C(Predicted) |
|---|---|
| Density | 1.574±0.06 g/cm3(Predicted) |
| Flash point | 131° |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Chloroform (Sparingly), Ethyl Acetate (Slightly) |
| form | Oil to Low-Melting Solid |
| form | Oil to Low-Melting Solid |
| color | Yellow to Light Brown |
| optical activity | 0.0900°(C=1g/100mL, CHCL3, 20°C, 589nm) |
| CAS DataBase Reference | 204205-33-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P | |||||||||
| HS Code | 2914.79.4000 | |||||||||
| NFPA 704 |
|
2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone price More Price(68)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | B6031 | 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone | 204205-33-4 | 1G | $34 | 2026-04-30 | Buy |
| TCI Chemical | B6031 | 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone | 204205-33-4 | 5G | $117 | 2026-04-30 | Buy |
| TRC | TRC-B688795-5G | 2-?Bromo-?2-?(2-?fluorophenyl)?-?1-?cyclopropylethanone (90% purity) | 204205-33-4 | 5g | $849 | 2026-06-03 | Buy |
| TRC | TRC-B688795-250MG | 2-?Bromo-?2-?(2-?fluorophenyl)?-?1-?cyclopropylethanone (90% purity) | 204205-33-4 | 250mg | $103 | 2026-06-03 | Buy |
| TRC | TRC-B688795-1G | 2-?Bromo-?2-?(2-?fluorophenyl)?-?1-?cyclopropylethanone (90% purity) | 204205-33-4 | 1g | $288 | 2026-06-03 | Buy |
2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone Chemical Properties,Uses,Production
Uses
2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone is a reagent used in the synthesis of potent anti-oxidant agents.
Synthesis
150322-73-9
204205-33-4
General procedure for the synthesis of 2-bromo-2-(2-fluorophenyl)-1-cyclopropylethanone from 1-cyclopropyl-2-(2-fluorophenyl)ethanone: 1-cyclopropyl-2-(2-fluorophenyl)ethanone (17.8 g, 100 mmol), iodine monobromide (62 g, 300 mmol), and 1-butyl-3-methylimidazolium bromide (8.7 g, 40 mmol) were dissolved in 150 mL of anhydrous tetrahydrofuran. The reaction was stirred at 40 °C for 4 hours. After completion of the reaction, the mixture was cooled to room temperature and the reaction was quenched by the addition of ice water. The reaction mixture was extracted with ethyl acetate and the organic phase was washed with saturated sodium bisulfite solution. The organic phase was concentrated and purified by recrystallization from ethanol to give 2-bromo-2-(2-fluorophenyl)-1-cyclopropylethanone (24.5 g, 95.3% yield, 99.73% purity).
References
[1] Patent: CN105884793, 2016, A. Location in patent: Paragraph 0033; 0034; 0035
[2] Patent: WO2013/14295, 2013, A1. Location in patent: Page/Page column 19-20
[3] Patent: WO2009/122440, 2009, A1. Location in patent: Page/Page column 31
[4] Patent: CN105884599, 2016, A. Location in patent: Paragraph 0025; 0062-0064
[5] Patent: CN104418718, 2018, B. Location in patent: Paragraph 0040; 0044; 0047; 0048; 0052; 0056
2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21586 | 55 |
| Anqing Chico Pharmaceutical Co., Ltd. | 15380796838 | chloewu@chicopharm.cn | CHINA | 340 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2950 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6366 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Shanghai Yingrui Biopharma Co.,Ltd | 21-33585366 | export01@shyrchem.com | CHINA | 1319 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8828 | 58 |
View Lastest Price from 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-06-15 | 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone
204205-33-4
|
$23.00 | 1kg | 99% | 50mt | Jinan Finer Chemical Co., Ltd | |
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2026-04-09 | 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone
204205-33-4
|
1KG Ton | 93%+ | 2 tons/month | ZHUHAI HRD PHARMACEUTICAL CO., LTD.
|
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2021-07-13 | 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone
204205-33-4
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-

- 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone
204205-33-4
- $23.00
- 99%
- Jinan Finer Chemical Co., Ltd
-

- 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone
204205-33-4
- $0.00
- 93%+
- ZHUHAI HRD PHARMACEUTICAL CO., LTD.
-

- 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone
204205-33-4
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
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